Author results

6K3J
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SOLUTION STRUCTURE OF APOBEC3G-CD2 WITH SSDNA, PRODUCT A
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G, DNA (5'-D(*AP*TP*TP*CP*UP*(IUR)P*AP*AP*TP*T)-3'), ZINC ION
Authors:Cao, C., Yan, X., Lan, W., Wang, C.
Deposit date:2019-05-19
Release date:2019-06-12
Method:SOLUTION NMR
Cite:Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Chem Asian J, 2019
6K3K
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SOLUTION STRUCTURE OF APOBEC3G-CD2 WITH SSDNA, PRODUCT B
Descriptor:DNA dC->dU-editing enzyme APOBEC-3G, DNA/RNA (5'-D(*AP*TP*TP*CP*UP*(ICY)P*AP*AP*TP*T)-3'), ZINC ION
Authors:Cao, C., Yan, X., Lan, W., Wang, C.
Deposit date:2019-05-19
Release date:2019-06-12
Method:SOLUTION NMR
Cite:Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Chem Asian J, 2019
6AJK
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CRYSTAL STRUCTURE OF TFB1M AND H45 IN HOMO SAPIENS
Descriptor:Dimethyladenosine transferase 1, mitochondrial, RNA (28-MER)
Authors:Liu, X., Shen, S., Wu, P., Li, F., Wang, C., Gong, Q., Wu, J., Zhang, H., Shi, Y.
Deposit date:2018-08-28
Release date:2019-06-05
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:Crystal structure of TFB1M and h45 in homo sapiens
To Be Published
6N9N
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CRYSTAL STRUCTURE OF MURINE GSDMD
Descriptor:Gasdermin-D
Authors:Liu, Z., Wang, C., Yang, J., Xiao, T.S.
Deposit date:2018-12-03
Release date:2019-06-05
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 2019
6N9O
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CRYSTAL STRUCTURE OF HUMAN GSDMD
Descriptor:Gasdermin-D
Authors:Liu, Z., Wang, C., Yang, J., Xiao, T.S.
Deposit date:2018-12-03
Release date:2019-06-05
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 2019
6NZK
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STRUCTURAL BASIS FOR HUMAN CORONAVIRUS ATTACHMENT TO SIALIC ACID RECEPTORS
Descriptor:Spike surface glycoprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Tortorici, M.A., Walls, A.C., Lang, Y., Wang, C., Li, Z., Koerhuis, D., Boons, G.J., Bosch, B.J., Rey, F.A., de Groot, R., Veesler, D.
Deposit date:2019-02-13
Release date:2019-06-05
Last modified:2019-06-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
6OHW
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STRUCTURAL BASIS FOR HUMAN CORONAVIRUS ATTACHMENT TO SIALIC ACID RECEPTORS. APO-HCOV-OC43 S
Descriptor:Spike surface glycoprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Tortorici, M.A., Walls, A.C., Lang, Y., Wang, C., Li, Z., Koerhuis, D., Boons, G.J., Bosch, B.J., Rey, F.A., de Groot, R., Veesler, D.
Deposit date:2019-04-07
Release date:2019-06-05
Last modified:2019-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
6NIV
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RACEMIC PHENOL-SOLUBLE MODULIN ALPHA 3 PEPTIDE
Descriptor:Phenol-soluble modulin PSM-alpha-3
Authors:Yao, Z., Cary, B.P., Bingman, C.A., Wang, C., Kreitler, D.F., Satyshur, K.A., Forest, K.T., Gellman, S.H.
Deposit date:2018-12-31
Release date:2019-05-15
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin alpha 3 Toxicity.
J.Am.Chem.Soc., 141, 2019
6OAU
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APO STRUCTURE OF WT LIPOPROTEIN LIPASE IN COMPLEX WITH GPIHBP1 MUTANT N78D N82D PRODUCED IN GNTI-DEFICIENT HEK293-F CELLS
Descriptor:Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Arora, R., Horton, P.A., Benson, T.E., Romanowski, M.J.
Deposit date:2019-03-18
Release date:2019-05-08
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OAZ
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APO STRUCTURE OF WT LIPOPROTEIN LIPASE IN COMPLEX WITH GPIHBP1 MUTANT N78D N82D PRODUCED IN HEK293-F CELLS
Descriptor:Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Arora, R., Horton, P.A., Benson, T.E., Romanowski, M.J.
Deposit date:2019-03-19
Release date:2019-05-08
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OB0
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COMPOUND 2 BOUND STRUCTURE OF WT LIPOPROTEIN LIPASE IN COMPLEX WITH GPIHBP1 MUTANT N78D N82D PRODUCED IN HEK293-F CELLS
Descriptor:Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Arora, R., Horton, P.A., Benson, T.E., Romanowski, M.J.
Deposit date:2019-03-19
Release date:2019-05-08
Last modified:2019-06-05
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6J1L
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CRYTAL STRUCTURE ANALYSIS OF THE ROR GAMMA(C455E)
Descriptor:Nuclear receptor ROR-gamma, 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide
Authors:zhang, Y., Li, C.C., wu, X.S.
Deposit date:2018-12-28
Release date:2019-05-01
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
J.Med.Chem., 62, 2019
6IF2
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COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR RUSC2
Descriptor:Ras-related protein Rab-35, Iporin, MAGNESIUM ION, ...
Authors:Lin, L., Zhu, J., Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6IF3
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COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR ACAP2
Descriptor:Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Ras-related protein Rab-35, ...
Authors:Lin, L., Zhu, J., Zhang, R.
Deposit date:2018-09-18
Release date:2019-04-03
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
6JCJ
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STRUCTURE OF CROLIBULIN IN COMPLEX WITH TUBULIN
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Zhang, Z., Yang, J.
Deposit date:2019-01-29
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
Biochem. Biophys. Res. Commun., 511, 2019
6NZS
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DEXTRANASE AODEX KQ11
Descriptor:Dextranase
Authors:Ren, W., Yan, W., Gu, L., Feng, Y., Dong, D., Wang, S., Wang, C., Lyu, M.
Deposit date:2019-02-14
Release date:2019-02-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of thermophilic dextranase from Thermoanaerobacter pseudethanolicus
To Be Published
6HL9
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CRYSTAL STRUCTURE OF THE CSID GLUTARATE HYDROXYLASE IN COMPLEX WITH SUCCINATE
Descriptor:Protein CsiD, FE (II) ION, SUCCINIC ACID
Authors:Williams, R.M., Mayans, O., Hartig, J.S.
Deposit date:2018-09-10
Release date:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate.
Nat Commun, 9, 2018
6AKJ
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THE CRYSTAL STRUCTURE OF EMC COMPLEX
Descriptor:Enhancer of rudimentary homolog,YTH domain-containing protein mmi1 fusion protein, SULFATE ION
Authors:Li, F.
Deposit date:2018-09-01
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing.
Nat Commun, 10, 2019
5Z6R
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SPASTIN AAA WITH ATP
Descriptor:Spastin, ADENOSINE-5'-TRIPHOSPHATE
Authors:Lin, Z., Wang, C., Shen, Y.
Deposit date:2018-01-25
Release date:2019-01-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:The Aaa Family Protein Spastin Severs A Microtubule
To Be Published
6GPN
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CRYSTAL STRUCTURE OF THE CSID GLUTARATE HYDROXYLASE IN COMPLEX WITH N-OXALYLGLYCINE
Descriptor:Protein CsiD, FE (II) ION, N-OXALYLGLYCINE
Authors:Williams, R.M., Mayans, O., Hartig, J.S.
Deposit date:2018-06-06
Release date:2019-01-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate.
Nat Commun, 9, 2018
6MUA
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CRYSTAL STRUCTURE OF CSM1-CSM4 SUBCOMPLEX IN THE TYPE III-A CRISPR-CSM INTERFERENCE COMPLEX
Descriptor:Uncharacterized protein Csm1, Uncharacterized protein Csm4
Authors:Jia, N., Patel, D.J.
Deposit date:2018-10-22
Release date:2019-01-09
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
5Z1R
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CRYSTAL STRUCTURE ANALYSIS OF THE BRD4
Descriptor:Bromodomain-containing protein 4, 5-bromo-N-(2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, 1,2-ETHANEDIOL, ...
Authors:Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C.
Deposit date:2017-12-28
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal Structure Analysis of the BRD4
To Be Published
5Z1S
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CRYSTAL STRUCTURE ANALYSIS OF THE BRD4(1)
Descriptor:Bromodomain-containing protein 4, 5-bromo-2-methoxy-N-(6-methoxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)benzene-1-sulfonamide, NITRATE ION, ...
Authors:Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C.
Deposit date:2017-12-28
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal Structure Analysis of the BRD4(1)
To Be Published
5Z1T
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CRYSTAL STRUCTURE ANALYSIS OF THE BRD4(1)
Descriptor:Bromodomain-containing protein 4, 5-bromo-N-(6-hydroxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, NITRATE ION, ...
Authors:Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C.
Deposit date:2017-12-28
Release date:2019-01-02
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Crystal Structure Analysis of the BRD4(1)
To Be Published
6A9X
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CRYSTAL STRUCTURE OF ANKG/GABARAP COMPLEX
Descriptor:Gamma-aminobutyric acid receptor-associated protein, Ankyrin-3
Authors:Wang, C., Li, J., Chen, K., Zhang, M.
Deposit date:2018-07-16
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP.
Mol. Psychiatry, 2018