6K3J | | SOLUTION STRUCTURE OF APOBEC3G-CD2 WITH SSDNA, PRODUCT A | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, DNA (5'-D(*AP*TP*TP*CP*UP*(IUR)P*AP*AP*TP*T)-3'), ZINC ION | | Authors: | Cao, C., Yan, X., Lan, W., Wang, C. | | Deposit date: | 2019-05-19 | | Release date: | 2019-06-12 | | Method: | SOLUTION NMR | | Cite: | Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Chem Asian J, 2019
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6K3K | | SOLUTION STRUCTURE OF APOBEC3G-CD2 WITH SSDNA, PRODUCT B | | Descriptor: | DNA dC->dU-editing enzyme APOBEC-3G, DNA/RNA (5'-D(*AP*TP*TP*CP*UP*(ICY)P*AP*AP*TP*T)-3'), ZINC ION | | Authors: | Cao, C., Yan, X., Lan, W., Wang, C. | | Deposit date: | 2019-05-19 | | Release date: | 2019-06-12 | | Method: | SOLUTION NMR | | Cite: | Structural Investigations on the Interactions between Cytidine Deaminase Human APOBEC3G and DNA.
Chem Asian J, 2019
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6AJK | | CRYSTAL STRUCTURE OF TFB1M AND H45 IN HOMO SAPIENS | | Descriptor: | Dimethyladenosine transferase 1, mitochondrial, RNA (28-MER) | | Authors: | Liu, X., Shen, S., Wu, P., Li, F., Wang, C., Gong, Q., Wu, J., Zhang, H., Shi, Y. | | Deposit date: | 2018-08-28 | | Release date: | 2019-06-05 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | Crystal structure of TFB1M and h45 in homo sapiens
To Be Published
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6N9N | | CRYSTAL STRUCTURE OF MURINE GSDMD | | Descriptor: | Gasdermin-D | | Authors: | Liu, Z., Wang, C., Yang, J., Xiao, T.S. | | Deposit date: | 2018-12-03 | | Release date: | 2019-06-05 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 2019
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6N9O | | CRYSTAL STRUCTURE OF HUMAN GSDMD | | Descriptor: | Gasdermin-D | | Authors: | Liu, Z., Wang, C., Yang, J., Xiao, T.S. | | Deposit date: | 2018-12-03 | | Release date: | 2019-06-05 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.
Immunity, 2019
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6NZK | | STRUCTURAL BASIS FOR HUMAN CORONAVIRUS ATTACHMENT TO SIALIC ACID RECEPTORS | | Descriptor: | Spike surface glycoprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Tortorici, M.A., Walls, A.C., Lang, Y., Wang, C., Li, Z., Koerhuis, D., Boons, G.J., Bosch, B.J., Rey, F.A., de Groot, R., Veesler, D. | | Deposit date: | 2019-02-13 | | Release date: | 2019-06-05 | | Last modified: | 2019-06-19 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
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6OHW | | STRUCTURAL BASIS FOR HUMAN CORONAVIRUS ATTACHMENT TO SIALIC ACID RECEPTORS. APO-HCOV-OC43 S | | Descriptor: | Spike surface glycoprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ... | | Authors: | Tortorici, M.A., Walls, A.C., Lang, Y., Wang, C., Li, Z., Koerhuis, D., Boons, G.J., Bosch, B.J., Rey, F.A., de Groot, R., Veesler, D. | | Deposit date: | 2019-04-07 | | Release date: | 2019-06-05 | | Last modified: | 2019-06-19 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis for human coronavirus attachment to sialic acid receptors.
Nat.Struct.Mol.Biol., 26, 2019
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6NIV | | RACEMIC PHENOL-SOLUBLE MODULIN ALPHA 3 PEPTIDE | | Descriptor: | Phenol-soluble modulin PSM-alpha-3 | | Authors: | Yao, Z., Cary, B.P., Bingman, C.A., Wang, C., Kreitler, D.F., Satyshur, K.A., Forest, K.T., Gellman, S.H. | | Deposit date: | 2018-12-31 | | Release date: | 2019-05-15 | | Last modified: | 2019-05-29 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Use of a Stereochemical Strategy To Probe the Mechanism of Phenol-Soluble Modulin alpha 3 Toxicity.
J.Am.Chem.Soc., 141, 2019
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6OAU | | APO STRUCTURE OF WT LIPOPROTEIN LIPASE IN COMPLEX WITH GPIHBP1 MUTANT N78D N82D PRODUCED IN GNTI-DEFICIENT HEK293-F CELLS | | Descriptor: | Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Arora, R., Horton, P.A., Benson, T.E., Romanowski, M.J. | | Deposit date: | 2019-03-18 | | Release date: | 2019-05-08 | | Last modified: | 2019-06-05 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OAZ | | APO STRUCTURE OF WT LIPOPROTEIN LIPASE IN COMPLEX WITH GPIHBP1 MUTANT N78D N82D PRODUCED IN HEK293-F CELLS | | Descriptor: | Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Arora, R., Horton, P.A., Benson, T.E., Romanowski, M.J. | | Deposit date: | 2019-03-19 | | Release date: | 2019-05-08 | | Last modified: | 2019-06-05 | | Method: | X-RAY DIFFRACTION (3.04 Å) | | Cite: | Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OB0 | | COMPOUND 2 BOUND STRUCTURE OF WT LIPOPROTEIN LIPASE IN COMPLEX WITH GPIHBP1 MUTANT N78D N82D PRODUCED IN HEK293-F CELLS | | Descriptor: | Lipoprotein lipase, Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Arora, R., Horton, P.A., Benson, T.E., Romanowski, M.J. | | Deposit date: | 2019-03-19 | | Release date: | 2019-05-08 | | Last modified: | 2019-06-05 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | Structure of lipoprotein lipase in complex with GPIHBP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6J1L | | CRYTAL STRUCTURE ANALYSIS OF THE ROR GAMMA(C455E) | | Descriptor: | Nuclear receptor ROR-gamma, 2-[4-(ethylsulfonyl)phenyl]-N-[2'-fluoro-4'-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)[1,1'-biphenyl]-4-yl]acetamide | | Authors: | zhang, Y., Li, C.C., wu, X.S. | | Deposit date: | 2018-12-28 | | Release date: | 2019-05-01 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable ROR gamma Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.
J.Med.Chem., 62, 2019
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6IF2 | | COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR RUSC2 | | Descriptor: | Ras-related protein Rab-35, Iporin, MAGNESIUM ION, ... | | Authors: | Lin, L., Zhu, J., Zhang, R. | | Deposit date: | 2018-09-18 | | Release date: | 2019-04-03 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
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6IF3 | | COMPLEX STRUCTURE OF RAB35 AND ITS EFFECTOR ACAP2 | | Descriptor: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2, Ras-related protein Rab-35, ... | | Authors: | Lin, L., Zhu, J., Zhang, R. | | Deposit date: | 2018-09-18 | | Release date: | 2019-04-03 | | Last modified: | 2019-05-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Rab35/ACAP2 and Rab35/RUSC2 Complex Structures Reveal Molecular Basis for Effector Recognition by Rab35 GTPase.
Structure, 27, 2019
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6JCJ | | STRUCTURE OF CROLIBULIN IN COMPLEX WITH TUBULIN | | Descriptor: | Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ... | | Authors: | Zhang, Z., Yang, J. | | Deposit date: | 2019-01-29 | | Release date: | 2019-03-13 | | Last modified: | 2019-03-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Molecular mechanism of crolibulin in complex with tubulin provides a rationale for drug design.
Biochem. Biophys. Res. Commun., 511, 2019
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6NZS | | DEXTRANASE AODEX KQ11 | | Descriptor: | Dextranase | | Authors: | Ren, W., Yan, W., Gu, L., Feng, Y., Dong, D., Wang, S., Wang, C., Lyu, M. | | Deposit date: | 2019-02-14 | | Release date: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal structure of thermophilic dextranase from Thermoanaerobacter pseudethanolicus
To Be Published
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6HL9 | |
6AKJ | | THE CRYSTAL STRUCTURE OF EMC COMPLEX | | Descriptor: | Enhancer of rudimentary homolog,YTH domain-containing protein mmi1 fusion protein, SULFATE ION | | Authors: | Li, F. | | Deposit date: | 2018-09-01 | | Release date: | 2019-02-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing.
Nat Commun, 10, 2019
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5Z6R | | SPASTIN AAA WITH ATP | | Descriptor: | Spastin, ADENOSINE-5'-TRIPHOSPHATE | | Authors: | Lin, Z., Wang, C., Shen, Y. | | Deposit date: | 2018-01-25 | | Release date: | 2019-01-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The Aaa Family Protein Spastin Severs A Microtubule
To Be Published
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6GPN | |
6MUA | |
5Z1R | | CRYSTAL STRUCTURE ANALYSIS OF THE BRD4 | | Descriptor: | Bromodomain-containing protein 4, 5-bromo-N-(2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, 1,2-ETHANEDIOL, ... | | Authors: | Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C. | | Deposit date: | 2017-12-28 | | Release date: | 2019-01-02 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Crystal Structure Analysis of the BRD4
To Be Published
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5Z1S | | CRYSTAL STRUCTURE ANALYSIS OF THE BRD4(1) | | Descriptor: | Bromodomain-containing protein 4, 5-bromo-2-methoxy-N-(6-methoxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)benzene-1-sulfonamide, NITRATE ION, ... | | Authors: | Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C. | | Deposit date: | 2017-12-28 | | Release date: | 2019-01-02 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Crystal Structure Analysis of the BRD4(1)
To Be Published
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5Z1T | | CRYSTAL STRUCTURE ANALYSIS OF THE BRD4(1) | | Descriptor: | Bromodomain-containing protein 4, 5-bromo-N-(6-hydroxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)-2-methoxybenzene-1-sulfonamide, NITRATE ION, ... | | Authors: | Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C. | | Deposit date: | 2017-12-28 | | Release date: | 2019-01-02 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Crystal Structure Analysis of the BRD4(1)
To Be Published
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6A9X | | CRYSTAL STRUCTURE OF ANKG/GABARAP COMPLEX | | Descriptor: | Gamma-aminobutyric acid receptor-associated protein, Ankyrin-3 | | Authors: | Wang, C., Li, J., Chen, K., Zhang, M. | | Deposit date: | 2018-07-16 | | Release date: | 2018-12-26 | | Method: | X-RAY DIFFRACTION (2.202 Å) | | Cite: | Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP.
Mol. Psychiatry, 2018
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