Author results

2E27
  • Download 2e27
  • View 2e27
Molmil generated image of 2e27
CRYSTAL STRUCTURE OF FV FRAGMENT OF ANTI-CIGUATOXIN ANTIBODY COMPLEXED WITH ABC-RING OF CIGUATOXIN
Descriptor:anti-ciguatoxin antibody, light chain, heavy chain, ...
Authors:Yokota, A., Tanaka, Y., Tsumoto, K.
Deposit date:2006-11-08
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49.
J.Biol.Chem., 283, 2008
5X08
  • Download 5x08
  • View 5x08
Molmil generated image of 5x08
CRYSTAL STRUCTURE OF BROADLY NEUTRALIZING ANTI-HIV-1 ANTIBODY 4E10, MUTANT NPRO, WITH PEPTIDE BOUND
Descriptor:Fab 4E10 Heavy chain, Fab 4E10 Light chain, Envelope glycoprotein gp160, ...
Authors:Caaveiro, J.M.M., Rujas, E., Nieva, J.L., Tsumoto, K.
Deposit date:2017-01-20
Release date:2017-04-05
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane
J. Mol. Biol., 429, 2017
3VTM
  • Download 3vtm
  • View 3vtm
Molmil generated image of 3vtm
STRUCTURE OF HEME TRANSPORT PROTEIN ISDH-NEAT3 FROM S. AUREUS IN COMPLEX WITH INDIUM-PORPHYRIN
Descriptor:Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING INDIUM, GLYCEROL
Authors:Vu, N.T., Caaveiro, J.M.M., Moriwaki, Y., Tsumoto, K.
Deposit date:2012-05-31
Release date:2013-05-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus
Protein Sci., 22, 2013
3VUA
  • Download 3vua
  • View 3vua
Molmil generated image of 3vua
APO ISDH-NEAT3 IN SPACE GROUP P3121 AT A RESOLUTION OF 1.85 A
Descriptor:Iron-regulated surface determinant protein H, SULFATE ION, ACETATE ION, ...
Authors:Vu, N.T., Caaveiro, J.M.M., Moriwaki, Y., Tsumoto, K.
Deposit date:2012-06-26
Release date:2013-06-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin
To be Published
1FKQ
  • Download 1fkq
  • View 1fkq
Molmil generated image of 1fkq
RECOMBINANT GOAT ALPHA-LACTALBUMIN T29V
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Horii, K., Matsushima, M., Tsumoto, K., Kumagai, I.
Deposit date:2000-08-10
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Contribution of Thr29 to the thermodynamic stability of goat alpha-lactalbumin as determined by experimental and theoretical approaches.
Proteins, 45, 2001
1FKV
  • Download 1fkv
  • View 1fkv
Molmil generated image of 1fkv
RECOMBINANT GOAT ALPHA-LACTALBUMIN T29I
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Horii, K., Matsushima, M., Tsumoto, K., Kumagai, I.
Deposit date:2000-08-10
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Contribution of Thr29 to the thermodynamic stability of goat alpha-lactalbumin as determined by experimental and theoretical approaches.
Proteins, 45, 2001
3QUG
  • Download 3qug
  • View 3qug
Molmil generated image of 3qug
STRUCTURE OF HEME TRANSPORT PROTEIN ISDH-NEAT3 FROM S. AUREUS IN COMPLEX WITH GALLIUM-PORPHYRIN
Descriptor:Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING GA, SULFATE ION, ...
Authors:Moriwaki, Y., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2011-02-24
Release date:2011-03-30
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus.
Biochemistry, 50, 2011
3QUH
  • Download 3quh
  • View 3quh
Molmil generated image of 3quh
STRUCTURE OF HEME TRANSPORT PROTEIN ISDH-NEAT3 FROM S. AUREUS IN COMPLEX WITH MANGANESE(III)-PORPHYRIN
Descriptor:Iron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING MN, GLYCEROL
Authors:Moriwaki, Y., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2011-02-24
Release date:2011-03-30
Last modified:2012-02-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus.
Biochemistry, 50, 2011
3ST7
  • Download 3st7
  • View 3st7
Molmil generated image of 3st7
CRYSTAL STRUCTURE OF CAPSULAR POLYSACCHARIDE ASSEMBLING PROTEIN CAPF FROM STAPHYLOCOCCUS AUREUS
Descriptor:Capsular polysaccharide synthesis enzyme Cap5F, ZINC ION, GLYCEROL
Authors:Miyafusa, T., Tanaka, Y., Kuroda, M., Yao, M., Watanabe, M., Ohta, T., Tanaka, I., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2011-07-09
Release date:2012-02-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains.
Biochem.J., 443, 2012
3VHR
  • Download 3vhr
  • View 3vhr
Molmil generated image of 3vhr
CRYSTAL STRUCTURE OF CAPSULAR POLYSACCHARIDE ASSEMBLING PROTEIN CAPF FROM STAPHYLOCOCCUS AUREUS IN SPACE GROUP C2221
Descriptor:Capsular polysaccharide synthesis enzyme Cap5F, ZINC ION, FORMIC ACID
Authors:Miyafusa, T., Yoshikazu, T., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2011-09-01
Release date:2012-02-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains.
Biochem.J., 443, 2012
6AF5
  • Download 6af5
  • View 6af5
Molmil generated image of 6af5
DJ-1 AFTER BACKSOAKING
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AF7
  • Download 6af7
  • View 6af7
Molmil generated image of 6af7
DJ-1 C106S UNBOUND
Descriptor:Protein/nucleic acid deglycase DJ-1, PENTAETHYLENE GLYCOL, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AF9
  • Download 6af9
  • View 6af9
Molmil generated image of 6af9
DJ-1 WITH ISATIN BOUND (HIGH CONCENTRATION)
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFA
  • Download 6afa
  • View 6afa
Molmil generated image of 6afa
DJ-1 WITH ISATIN (LOW CONCENTRATION)
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFB
  • Download 6afb
  • View 6afb
Molmil generated image of 6afb
DJ-1 C106S INCUBATED WITH ISATIN
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION, ...
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFC
  • Download 6afc
  • View 6afc
Molmil generated image of 6afc
DJ-1 WITH COMPOUND 4
Descriptor:Protein/nucleic acid deglycase DJ-1, 5-fluoranyl-1~{H}-indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFD
  • Download 6afd
  • View 6afd
Molmil generated image of 6afd
DJ-1 WITH COMPOUND 6
Descriptor:Protein/nucleic acid deglycase DJ-1, 7-methyl-1~{H}-indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFE
  • Download 6afe
  • View 6afe
Molmil generated image of 6afe
DJ-1 WITH COMPOUND 7
Descriptor:Protein/nucleic acid deglycase DJ-1, 7-(trifluoromethyl)-1~{H}-indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFF
  • Download 6aff
  • View 6aff
Molmil generated image of 6aff
DJ-1 WITH COMPOUND 8
Descriptor:Protein/nucleic acid deglycase DJ-1, methyl 2,3-bis(oxidanylidene)-1~{H}-indole-7-carboxylate, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFG
  • Download 6afg
  • View 6afg
Molmil generated image of 6afg
DJ-1 WITH COMPOUND 9
Descriptor:Protein/nucleic acid deglycase DJ-1, 1-methylindole-2,3-dione
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFH
  • Download 6afh
  • View 6afh
Molmil generated image of 6afh
DJ-1 WITH COMPOUND 10
Descriptor:Protein/nucleic acid deglycase DJ-1, 1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFI
  • Download 6afi
  • View 6afi
Molmil generated image of 6afi
DJ-1 WITH COMPOUND 11
Descriptor:Protein/nucleic acid deglycase DJ-1, 1-ethylindole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFJ
  • Download 6afj
  • View 6afj
Molmil generated image of 6afj
DJ-1 WITH COMPOUND 13
Descriptor:Protein/nucleic acid deglycase DJ-1, butyl 2-[2,3-bis(oxidanylidene)indol-1-yl]ethanoate, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFL
  • Download 6afl
  • View 6afl
Molmil generated image of 6afl
DJ-1 WITH COMPOUND 15
Descriptor:Protein/nucleic acid deglycase DJ-1, 5-fluoranyl-1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
1HMK
  • Download 1hmk
  • View 1hmk
Molmil generated image of 1hmk
RECOMBINANT GOAT ALPHA-LACTALBUMIN
Descriptor:PROTEIN (ALPHA-LACTALBUMIN), CALCIUM ION
Authors:Horii, K., Matsushima, M., Tsumoto, K., Kumagai, I.
Deposit date:1998-11-26
Release date:1999-11-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Effect of the extra n-terminal methionine residue on the stability and folding of recombinant alpha-lactalbumin expressed in Escherichia coli.
J.Mol.Biol., 285, 1999