Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Manganese(III)-porphyrin

Summary for 3QUH

DescriptorIron-regulated surface determinant protein H, PROTOPORPHYRIN IX CONTAINING MN, GLYCEROL, ... (4 entities in total)
Functional Keywordsmanganese (iii), metalloporphyrin, metal selectivity, neat domain, heme binding, heme transport, heme, hemin, ppix, protoporphyrin ix, cell wall, heme-binding protein
Biological sourceStaphylococcus aureus
Cellular locationSecreted, cell wall; Peptidoglycan-anchor (Potential) Q931P4
Total number of polymer chains2
Total molecular weight30289.36
Moriwaki, Y.,Caaveiro, J.M.M.,Tsumoto, K. (deposition date: 2011-02-24, release date: 2011-03-30, Last modification date: 2012-02-15)
Primary citation
Moriwaki, Y.,Caaveiro, J.M.M.,Tanaka, Y.,Tsutsumi, H.,Hamachi, I.,Tsumoto, K.
Molecular basis of recognition of antibacterial porphyrins by heme-transporter IsdH-NEAT3 of Staphylococcus aureus.
Biochemistry, 50:7311-7320, 2011
PubMed: 21797259 (PDB entries with the same primary citation)
DOI: 10.1021/bi200493h
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.293603.9%4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution