Author results

3R4S
  • Download 3r4s
  • View 3r4s
Molmil generated image of 3r4s
CELL ENTRY OF BOTULINUM NEUROTOXIN TYPE C IS DEPENDENT UPON INTERACTION WITH TWO GANGLIOSIDE MOLECULES
Descriptor:Botulinum neurotoxin type C1, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, O-SIALIC ACID
Authors:Strotmeier, J., Gu, S., Jutzi, S., Mahrhold, S., Zhou, J., Pich, A., Bigalke, H., Rummel, A., Jin, R., Binz, T.
Deposit date:2011-03-17
Release date:2011-06-08
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
3R4U
  • Download 3r4u
  • View 3r4u
Molmil generated image of 3r4u
CELL ENTRY OF BOTULINUM NEUROTOXIN TYPE C IS DEPENDENT UPON INTERACTION WITH TWO GANGLIOSIDE MOLECULES
Descriptor:Botulinum neurotoxin type C1
Authors:Strotmeier, J., Gu, S., Jutzi, S., Mahrhold, S., Zhou, J., Pich, A., Bigalke, H., Rummel, A., Jin, R., Binz, T.
Deposit date:2011-03-17
Release date:2011-06-08
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites.
Mol.Microbiol., 81, 2011
3V0A
  • Download 3v0a
  • View 3v0a
Molmil generated image of 3v0a
2.7 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA
Descriptor:BoNT/A, NTNH, Llama antibody F12, ...
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
3V0B
  • Download 3v0b
  • View 3v0b
Molmil generated image of 3v0b
3.9 ANGSTROM CRYSTAL STRUCTURE OF BONT/AI IN COMPLEX WITH NTNHA
Descriptor:BoNT/A, NTNH, ZINC ION, ...
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
3V0C
  • Download 3v0c
  • View 3v0c
Molmil generated image of 3v0c
4.3 ANGSTROM CRYSTAL STRUCTURE OF AN INACTIVE BONT/A (E224Q/R363A/Y366F)
Descriptor:BoNT/A, ZINC ION
Authors:Gu, S., Rumpel, S., Zhou, J., Strotmeier, J., Bigalke, H., Perry, K., Shoemaker, C.B., Rummel, A., Jin, R.
Deposit date:2011-12-07
Release date:2012-03-14
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
Science, 335, 2012
4LO0
  • Download 4lo0
  • View 4lo0
Molmil generated image of 4lo0
APO HA17-HA33
Descriptor:HA-33, HA-17
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.055 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO1
  • Download 4lo1
  • View 4lo1
Molmil generated image of 4lo1
HA17-HA33-GAL
Descriptor:HA-33, HA-17, BETA-D-GALACTOSE
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO2
  • Download 4lo2
  • View 4lo2
Molmil generated image of 4lo2
HA17-HA33-LAC
Descriptor:HA-33, HA-17, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO3
  • Download 4lo3
  • View 4lo3
Molmil generated image of 4lo3
HA17-HA33-LACNAC
Descriptor:HA-33, HA-17, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.249 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO4
  • Download 4lo4
  • View 4lo4
Molmil generated image of 4lo4
APO HA-70
Descriptor:HA-70, CHLORIDE ION
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.871 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO5
  • Download 4lo5
  • View 4lo5
Molmil generated image of 4lo5
HA70-ALPHA2,3-SIALC
Descriptor:HA-70, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO6
  • Download 4lo6
  • View 4lo6
Molmil generated image of 4lo6
HA70-ALPHA2,6-SIALC
Descriptor:HA-70, O-SIALIC ACID, BETA-D-GALACTOSE, ...
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO7
  • Download 4lo7
  • View 4lo7
Molmil generated image of 4lo7
HA70(D3)-HA17-HA33
Descriptor:HA-70, HA-33, HA-17
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.73 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
4LO8
  • Download 4lo8
  • View 4lo8
Molmil generated image of 4lo8
HA70(D3)-HA17
Descriptor:HA-70, HA-17
Authors:Lee, K., Gu, S., Jin, L., Le, T.T., Cheng, L.W., Strotmeier, J., Kruel, A.M., Yao, G., Perry, K., Rummel, A., Jin, R.
Deposit date:2013-07-12
Release date:2013-10-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a Bimodular Botulinum Neurotoxin Complex Provides Insights into Its Oral Toxicity.
Plos Pathog., 9, 2013
3OBR
  • Download 3obr
  • View 3obr
Molmil generated image of 3obr
CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE D BINDING DOMAIN
Descriptor:Botulinum neurotoxin type D, GLYCEROL
Authors:Zong, Y., Lee, K.K., Jin, R.
Deposit date:2010-08-09
Release date:2010-09-08
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
Biochem.J., 431, 2010
3OBT
  • Download 3obt
  • View 3obt
Molmil generated image of 3obt
CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE D LIGAND BINDING DOMAIN IN COMPLEX WITH N-ACETYLNEURAMINIC ACID
Descriptor:Botulinum neurotoxin type D, 5-N-ACETYL-BETA-D-NEURAMINIC ACID, GLYCEROL
Authors:Lee, K.K., Zong, Y., Jin, R.
Deposit date:2010-08-09
Release date:2010-09-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
Biochem.J., 431, 2010