Author results

1BIR
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RIBONUCLEASE T1, PHE 100 TO ALA MUTANT COMPLEXED WITH 2' GMP
Descriptor:RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Doumen, J., Gonciarz, M., Zegers, I., Loris, R., Wyns, L., Steyaert, J.
Deposit date:1996-01-04
Release date:1996-08-17
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.
Protein Sci., 5, 1996
1LRA
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CRYSTALLOGRAPHIC STUDY OF GLU 58 ALA RNASE T1(ASTERISK)2'-GUANOSINE MONOPHOSPHATE AT 1.9 ANGSTROMS RESOLUTION
Descriptor:RIBONUCLEASE T1, SODIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Pletinckx, J., Steyaert, J., Choe, H.-W., Heinemann, U., Wyns, L.
Deposit date:1993-10-01
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic study of Glu58Ala RNase T1 x 2'-guanosine monophosphate at 1.9-A resolution.
Biochemistry, 33, 1994
1YOE
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CRYSTAL STRUCTURE OF A THE E. COLI PYRIMIDINE NUCLEOSIDE HYDROLASE YBEK WITH BOUND RIBOSE
Descriptor:Hypothetical protein ybeK, RIBOSE, CALCIUM ION
Authors:Muzzolini, L., Versees, W., Steyaert, J., Degano, M.
Deposit date:2005-01-27
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of the E. coli pyrimidine nucleoside hydrolase YbeK with bound ribose
To be Published
2NXW
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CRYSTAL STRUCTURE OF PHENYLPYRUVATE DECARBOXYLASE OF AZOSPIRILLUM BRASILENSE
Descriptor:PHENYL-3-PYRUVATE DECARBOXYLASE, MAGNESIUM ION, CHLORIDE ION, ...
Authors:Versees, W., Spaepen, S., Vanderleyden, J., Steyaert, J.
Deposit date:2006-11-20
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism.
Febs J., 274, 2007
2X1O
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GELSOLIN NANOBODY
Descriptor:GELSOLIN NANOBODY
Authors:Van Den Abbeele, A., Declercq, S., De Ganck, A., De Corte, V., Van Loo, B., Srinivasan, V., Steyaert, J., Van De Kerckhove, J., Gettemans, J.
Deposit date:2010-01-03
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
2X1P
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GELSOLIN NANOBODY
Descriptor:GELSOLIN NANOBODY
Authors:Van Den Abbeele, A., Declercq, S., De Ganck, A., De Corte, V., Van Loo, B., Srinivasan, V., Steyaert, J., Van De Kerckhove, J., Gettemans, J.
Deposit date:2010-01-03
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
2X1Q
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GELSOLIN NANOBODY
Descriptor:GELSOLIN NANOBODY
Authors:Van Den Abbeele, A., Declercq, S., De Ganck, A., De Corte, V., Van Loo, B., Srinivasan, V., Steyaert, J., Van De Kerckhove, J., Gettemans, J.
Deposit date:2010-01-03
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
2X6M
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STRUCTURE OF A SINGLE DOMAIN CAMELID ANTIBODY FRAGMENT IN COMPLEX WITH A C-TERMINAL PEPTIDE OF ALPHA-SYNUCLEIN
Descriptor:HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY, ALPHA-SYNUCLEIN PEPTIDE
Authors:DeGenst, E., Guilliams, T., Wellens, J., O'Day, E.M., Waudby, C.A., Meehan, S., Dumoulin, M., Hsu, S.-T.D., Cremades, N., Verschueren, K.H.G., Pardon, E., Wyns, L., Steyaert, J., Christodoulou, J., Dobson, C.M.
Deposit date:2010-02-18
Release date:2010-06-23
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
4MQS
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STRUCTURE OF ACTIVE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO THE AGONIST IPEROXO
Descriptor:Muscarinic acetylcholine receptor M2, Nanobody 9-8, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium
Authors:Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Huebner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K.
Deposit date:2013-09-16
Release date:2013-11-27
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
4MQT
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STRUCTURE OF ACTIVE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO THE AGONIST IPEROXO AND ALLOSTERIC MODULATOR LY2119620
Descriptor:Muscarinic acetylcholine receptor M2, Nanobody 9-8, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, ...
Authors:Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Huebner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K.
Deposit date:2013-09-16
Release date:2013-11-27
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
1BU4
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RIBONUCLEASE 1 COMPLEX WITH 2'GMP
Descriptor:RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:Loris, R., Devos, S., Langhorst, U., Decanniere, K., Bouckaert, J., Maes, D., Transue, T.R., Steyaert, J.
Deposit date:1998-09-11
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
1BVI
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RIBONUCLEASE T1 (WILDTYPE) COMPLEXED WITH 2'GMP
Descriptor:PROTEIN (RIBONUCLEASE T1), GUANOSINE-2'-MONOPHOSPHATE, CALCIUM ION
Authors:Langhorst, U., Loris, R., Denisov, V.P., Doumen, J., Roose, P., Maes, D., Halle, B., Steyaert, J.
Deposit date:1998-09-15
Release date:1998-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
1FYS
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RIBONUCLEASE T1 V16C MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Loris, R., Steyaert, J.
Deposit date:2000-10-03
Release date:2000-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
1FZU
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RNASE T1 V78A MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Loris, R., Steyaert, J.
Deposit date:2000-10-04
Release date:2000-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
1G02
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RIBONUCLEASE T1 V16S MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Loris, R., Steyaert, J.
Deposit date:2000-10-05
Release date:2000-10-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
1HOZ
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CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX
Descriptor:INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE, CALCIUM ION, GLYCEROL
Authors:Versees, W., Decanniere, K., Pelle, R., Depoorter, J., Parkin, D.W., Steyaert, J.
Deposit date:2000-12-12
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
J.Mol.Biol., 307, 2001
1HP0
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CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX IN COMPLEX WITH THE SUBSTRATE ANALOGUE 3-DEAZA-ADENOSINE
Descriptor:INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE, CALCIUM ION, 3-DEAZA-ADENOSINE
Authors:Versees, W., Decanniere, K., Pelle, R., Depoorter, J., Parkin, D.W., Steyaert, J.
Deposit date:2000-12-12
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
J.Mol.Biol., 307, 2001
1HYF
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RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH SR2+
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, STRONTIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-19
Release date:2001-02-14
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1HZ1
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RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH MG2+
Descriptor:RIBONUCLEASE T1, MAGNESIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-23
Release date:2001-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I0V
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RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM I CRYSTAL)
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-30
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.234 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I0X
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RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM II CRYSTAL)
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, GUANOSINE-2'-MONOPHOSPHATE, CALCIUM ION
Authors:De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R.
Deposit date:2001-01-30
Release date:2001-02-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I2E
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RIBONUCLEASE T1 V16A MUTANT, FORM I
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-09
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I2F
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RIBONUCLEASE T1 V16A MUTANT, FORM II
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-09
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I2G
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RIBONUCLEASE T1 V16T MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-09
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I3F
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RIBONUCLEASE T1 V89S MUTANT
Descriptor:GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE
Authors:De Vos, S., Backmann, J., Steyaert, J., Loris, R.
Deposit date:2001-02-15
Release date:2001-03-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001