1BIR | | RIBONUCLEASE T1, PHE 100 TO ALA MUTANT COMPLEXED WITH 2' GMP | | Descriptor: | RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | Doumen, J., Gonciarz, M., Zegers, I., Loris, R., Wyns, L., Steyaert, J. | | Deposit date: | 1996-01-04 | | Release date: | 1996-08-17 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A catalytic function for the structurally conserved residue Phe 100 of ribonuclease T1.
Protein Sci., 5, 1996
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1LRA | | CRYSTALLOGRAPHIC STUDY OF GLU 58 ALA RNASE T1(ASTERISK)2'-GUANOSINE MONOPHOSPHATE AT 1.9 ANGSTROMS RESOLUTION | | Descriptor: | RIBONUCLEASE T1, SODIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | Pletinckx, J., Steyaert, J., Choe, H.-W., Heinemann, U., Wyns, L. | | Deposit date: | 1993-10-01 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic study of Glu58Ala RNase T1 x 2'-guanosine monophosphate at 1.9-A resolution.
Biochemistry, 33, 1994
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1YOE | |
2NXW | | CRYSTAL STRUCTURE OF PHENYLPYRUVATE DECARBOXYLASE OF AZOSPIRILLUM BRASILENSE | | Descriptor: | PHENYL-3-PYRUVATE DECARBOXYLASE, MAGNESIUM ION, CHLORIDE ION, ... | | Authors: | Versees, W., Spaepen, S., Vanderleyden, J., Steyaert, J. | | Deposit date: | 2006-11-20 | | Release date: | 2007-05-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanism.
Febs J., 274, 2007
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2X1O | | GELSOLIN NANOBODY | | Descriptor: | GELSOLIN NANOBODY | | Authors: | Van Den Abbeele, A., Declercq, S., De Ganck, A., De Corte, V., Van Loo, B., Srinivasan, V., Steyaert, J., Van De Kerckhove, J., Gettemans, J. | | Deposit date: | 2010-01-03 | | Release date: | 2011-01-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
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2X1P | | GELSOLIN NANOBODY | | Descriptor: | GELSOLIN NANOBODY | | Authors: | Van Den Abbeele, A., Declercq, S., De Ganck, A., De Corte, V., Van Loo, B., Srinivasan, V., Steyaert, J., Van De Kerckhove, J., Gettemans, J. | | Deposit date: | 2010-01-03 | | Release date: | 2011-01-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
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2X1Q | | GELSOLIN NANOBODY | | Descriptor: | GELSOLIN NANOBODY | | Authors: | Van Den Abbeele, A., Declercq, S., De Ganck, A., De Corte, V., Van Loo, B., Srinivasan, V., Steyaert, J., Van De Kerckhove, J., Gettemans, J. | | Deposit date: | 2010-01-03 | | Release date: | 2011-01-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.06 Å) | | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction.
Cell.Mol.Life Sci., 67, 2010
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2X6M | | STRUCTURE OF A SINGLE DOMAIN CAMELID ANTIBODY FRAGMENT IN COMPLEX WITH A C-TERMINAL PEPTIDE OF ALPHA-SYNUCLEIN | | Descriptor: | HEAVY CHAIN VARIABLE DOMAIN FROM DROMEDARY, ALPHA-SYNUCLEIN PEPTIDE | | Authors: | DeGenst, E., Guilliams, T., Wellens, J., O'Day, E.M., Waudby, C.A., Meehan, S., Dumoulin, M., Hsu, S.-T.D., Cremades, N., Verschueren, K.H.G., Pardon, E., Wyns, L., Steyaert, J., Christodoulou, J., Dobson, C.M. | | Deposit date: | 2010-02-18 | | Release date: | 2010-06-23 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Structure and Properties of a Complex of Alpha-Synuclein and a Single-Domain Camelid Antibody.
J.Mol.Biol., 402, 2010
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4MQS | | STRUCTURE OF ACTIVE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO THE AGONIST IPEROXO | | Descriptor: | Muscarinic acetylcholine receptor M2, Nanobody 9-8, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium | | Authors: | Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Huebner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K. | | Deposit date: | 2013-09-16 | | Release date: | 2013-11-27 | | Last modified: | 2017-07-05 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
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4MQT | | STRUCTURE OF ACTIVE HUMAN M2 MUSCARINIC ACETYLCHOLINE RECEPTOR BOUND TO THE AGONIST IPEROXO AND ALLOSTERIC MODULATOR LY2119620 | | Descriptor: | Muscarinic acetylcholine receptor M2, Nanobody 9-8, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, ... | | Authors: | Kruse, A.C., Ring, A.M., Manglik, A., Hu, J., Hu, K., Eitel, K., Huebner, H., Pardon, E., Valant, C., Sexton, P.M., Christopoulos, A., Felder, C.C., Gmeiner, P., Steyaert, J., Weis, W.I., Garcia, K.C., Wess, J., Kobilka, B.K. | | Deposit date: | 2013-09-16 | | Release date: | 2013-11-27 | | Last modified: | 2019-05-01 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
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1BU4 | | RIBONUCLEASE 1 COMPLEX WITH 2'GMP | | Descriptor: | RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | Loris, R., Devos, S., Langhorst, U., Decanniere, K., Bouckaert, J., Maes, D., Transue, T.R., Steyaert, J. | | Deposit date: | 1998-09-11 | | Release date: | 1999-02-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
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1BVI | | RIBONUCLEASE T1 (WILDTYPE) COMPLEXED WITH 2'GMP | | Descriptor: | PROTEIN (RIBONUCLEASE T1), GUANOSINE-2'-MONOPHOSPHATE, CALCIUM ION | | Authors: | Langhorst, U., Loris, R., Denisov, V.P., Doumen, J., Roose, P., Maes, D., Halle, B., Steyaert, J. | | Deposit date: | 1998-09-15 | | Release date: | 1998-09-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Dissection of the structural and functional role of a conserved hydration site in RNase T1.
Protein Sci., 8, 1999
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1FYS | | RIBONUCLEASE T1 V16C MUTANT | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Vos, S., Loris, R., Steyaert, J. | | Deposit date: | 2000-10-03 | | Release date: | 2000-10-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
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1FZU | | RNASE T1 V78A MUTANT | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Vos, S., Loris, R., Steyaert, J. | | Deposit date: | 2000-10-04 | | Release date: | 2000-10-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
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1G02 | | RIBONUCLEASE T1 V16S MUTANT | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Vos, S., Loris, R., Steyaert, J. | | Deposit date: | 2000-10-05 | | Release date: | 2000-10-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
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1HOZ | | CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX | | Descriptor: | INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE, CALCIUM ION, GLYCEROL | | Authors: | Versees, W., Decanniere, K., Pelle, R., Depoorter, J., Parkin, D.W., Steyaert, J. | | Deposit date: | 2000-12-12 | | Release date: | 2001-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
J.Mol.Biol., 307, 2001
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1HP0 | | CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX IN COMPLEX WITH THE SUBSTRATE ANALOGUE 3-DEAZA-ADENOSINE | | Descriptor: | INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE, CALCIUM ION, 3-DEAZA-ADENOSINE | | Authors: | Versees, W., Decanniere, K., Pelle, R., Depoorter, J., Parkin, D.W., Steyaert, J. | | Deposit date: | 2000-12-12 | | Release date: | 2001-12-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
J.Mol.Biol., 307, 2001
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1HYF | | RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH SR2+ | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, STRONTIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R. | | Deposit date: | 2001-01-19 | | Release date: | 2001-02-14 | | Last modified: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
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1HZ1 | | RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH MG2+ | | Descriptor: | RIBONUCLEASE T1, MAGNESIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R. | | Deposit date: | 2001-01-23 | | Release date: | 2001-01-31 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
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1I0V | | RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM I CRYSTAL) | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R. | | Deposit date: | 2001-01-30 | | Release date: | 2001-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.234 Å) | | Cite: | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
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1I0X | | RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM II CRYSTAL) | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, GUANOSINE-2'-MONOPHOSPHATE, CALCIUM ION | | Authors: | De Swarte, J., De Vos, S., Langhorst, U., Steyaert, J., Loris, R. | | Deposit date: | 2001-01-30 | | Release date: | 2001-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
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1I2E | | RIBONUCLEASE T1 V16A MUTANT, FORM I | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Vos, S., Backmann, J., Steyaert, J., Loris, R. | | Deposit date: | 2001-02-09 | | Release date: | 2001-03-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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1I2F | | RIBONUCLEASE T1 V16A MUTANT, FORM II | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Vos, S., Backmann, J., Steyaert, J., Loris, R. | | Deposit date: | 2001-02-09 | | Release date: | 2001-03-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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1I2G | | RIBONUCLEASE T1 V16T MUTANT | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Vos, S., Backmann, J., Steyaert, J., Loris, R. | | Deposit date: | 2001-02-09 | | Release date: | 2001-03-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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1I3F | | RIBONUCLEASE T1 V89S MUTANT | | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE T1, CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE | | Authors: | De Vos, S., Backmann, J., Steyaert, J., Loris, R. | | Deposit date: | 2001-02-15 | | Release date: | 2001-03-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
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