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1BSV
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GDP-FUCOSE SYNTHETASE FROM ESCHERICHIA COLI COMPLEX WITH NADPH
Descriptor:PROTEIN (GDP-FUCOSE SYNTHETASE), NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Somers, W.S., Stahl, M.L., Sullivan, F.X.
Deposit date:1998-08-31
Release date:1999-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site.
Structure, 6, 1998
1FXS
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GDP-FUCOSE SYNTHETASE FROM ESCHERICHIA COLI COMPLEX WITH NADP
Descriptor:PROTEIN (GDP-FUCOSE SYNTHETASE), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Somers, W.S., Stahl, M.L., Sullivan, F.X.
Deposit date:1998-09-01
Release date:1999-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site.
Structure, 6, 1998
1GFS
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GDP-FUCOSE SYNTHETASE FROM E. COLI
Descriptor:GDP-FUCOSE SYNTHETASE
Authors:Somers, W.S., Stahl, M.L., Sullivan, F.X.
Deposit date:1998-08-17
Release date:1999-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:GDP-fucose synthetase from Escherichia coli: structure of a unique member of the short-chain dehydrogenase/reductase family that catalyzes two distinct reactions at the same active site.
Structure, 6, 1998
1KAM
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STRUCTURE OF BACILLUS SUBTILIS NICOTINIC ACID MONONUCLEOTIDE ADENYLYL TRANSFERASE
Descriptor:NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE
Authors:Olland, A.M., Underwood, K.W., Czerwinski, R.M., Lo, M.C., Aulabaugh, A., Bard, J., Stahl, M.L., Somers, W.S., Sullivan, F.X., Chopra, R.
Deposit date:2001-11-02
Release date:2002-07-12
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase.
J.Biol.Chem., 277, 2002
1KAQ
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STRUCTURE OF BACILLUS SUBTILIS NICOTINIC ACID MONONUCLEOTIDE ADENYLYL TRANSFERASE
Descriptor:NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE, NICOTINIC ACID ADENINE DINUCLEOTIDE
Authors:Olland, A.M., Underwood, K.W., Czerwinski, R.M., Lo, M.C., Aulabaugh, A., Bard, J., Stahl, M.L., Somers, W.S., Sullivan, F.X., Chopra, R.
Deposit date:2001-11-02
Release date:2002-07-12
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase.
J.Biol.Chem., 277, 2002
1NXK
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CRYSTAL STRUCTURE OF STAUROSPORINE BOUND TO MAP KAP KINASE 2
Descriptor:MAP kinase-activated protein kinase 2, STAUROSPORINE, SULFATE ION
Authors:Underwood, K.W., Parris, K.D., Federico, E., Mosyak, L., Czerwinski, R.M., Shane, T., Taylor, M., Svenson, K., Liu, Y., Hsiao, C.L., Wolfrom, S., Malakian, K., Telliez, J.B., Lin, L.L., Kriz, R.W., Seehra, J., Somers, W.S., Stahl, M.L.
Deposit date:2003-02-10
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme
Structure, 11, 2003
1NY3
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CRYSTAL STRUCTURE OF ADP BOUND TO MAP KAP KINASE 2
Descriptor:MAP kinase-activated protein kinase 2, ADENOSINE-5'-DIPHOSPHATE
Authors:Underwood, K.W., Parris, K.D., Federico, E., Mosyak, L., Shane, T., Taylor, M., Svenson, K., Liu, Y., Hsiao, C.L., Wolfrom, S., Maguire, M., Malakian, K., Telliez, J.B., Lin, L.L., Kriz, R.W., Seehra, J., Somers, W.S., Stahl, M.L.
Deposit date:2003-02-11
Release date:2003-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme
Structure, 11, 2003
1SQ0
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE WILD-TYPE VON WILLEBRAND FACTOR A1 DOMAIN AND GLYCOPROTEIN IB ALPHA AT 2.6 ANGSTROM RESOLUTION
Descriptor:Von Willebrand factor (vWF) [Contains: Von Willebrand antigen II], Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha) (GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B) [Contains: Glycocalicin]
Authors:Dumas, J.J., Kumar, R., McDonagh, T., Sullivan, F., Stahl, M.L., Somers, W.S., Mosyak, L.
Deposit date:2004-03-17
Release date:2004-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the wild-type von Willebrand factor A1-glycoprotein Ibalpha complex reveals conformation differences with a complex bearing von Willebrand disease mutations
J.Biol.Chem., 279, 2004
1U9E
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-397
Descriptor:Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL
Authors:Manas, E.S., Unwalla, R.J., Xu, Z.B., Malamas, M.S., Miller, C.P., Harris, H.A., Hsiao, C., Akopian, T., Hum, W.T., Malakian, K., Wolfrom, S., Bapat, A., Bhat, R.A., Stahl, M.L., Somers, W.S., Alvarez, J.C.
Deposit date:2004-08-09
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-Based Design Of Estrogen Receptor-beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
1X76
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-697
Descriptor:Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
Authors:Manas, E.S., Unwalla, R.J., Xu, Z.B., Malamas, M.S., Miller, C.P., Harris, H.A., Hsiao, C., Akopian, T., Hum, W.T., Malakian, K., Wolfrom, S., Bapat, A., Bhat, R.A., Stahl, M.L., Somers, W.S., Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
1X78
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-244
Descriptor:Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
Authors:Manas, E.S., Unwalla, R.J., Xu, Z.B., Malamas, M.S., Miller, C.P., Harris, H.A., Hsiao, C., Akopian, T., Hum, W.T., Malakian, K., Wolfrom, S., Bapat, A., Bhat, R.A., Stahl, M.L., Somers, W.S., Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
1X7B
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH ERB-041
Descriptor:Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL
Authors:Manas, E.S., Unwalla, R.J., Xu, Z.B., Malamas, M.S., Miller, C.P., Harris, H.A., Hsiao, C., Akopian, T., Hum, W.T., Malakian, K., Wolfrom, S., Bapat, A., Bhat, R.A., Stahl, M.L., Somers, W.S., Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
1X7E
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CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED WITH WAY-244
Descriptor:Estrogen receptor 1 (alpha), steroid receptor coactivator-3, [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
Authors:Manas, E.S., Unwalla, R.J., Xu, Z.B., Malamas, M.S., Miller, C.P., Harris, H.A., Hsiao, C., Akopian, T., Hum, W.T., Malakian, K., Wolfrom, S., Bapat, A., Bhat, R.A., Stahl, M.L., Somers, W.S., Alvarez, J.C.
Deposit date:2004-08-13
Release date:2005-03-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Estrogen Receptor-Beta Selective Ligands
J.Am.Chem.Soc., 126, 2004
2ID5
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CRYSTAL STRUCTURE OF THE LINGO-1 ECTODOMAIN
Descriptor:Leucine rich repeat neuronal 6A, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
Authors:Mosyak, L., Wood, A., Dwyer, B., Johnson, M., Stahl, M.L., Somers, W.S.
Deposit date:2006-09-14
Release date:2006-09-26
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
J.Biol.Chem., 281, 2006
1DB3
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E.COLI GDP-MANNOSE 4,6-DEHYDRATASE
Descriptor:GDP-MANNOSE 4,6-DEHYDRATASE
Authors:Somoza, J.R., Menon, S., Somers, W.S., Sullivan, F.X.
Deposit date:1999-11-02
Release date:1999-11-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and kinetic analysis of Escherichia coli GDP-mannose 4,6 dehydratase provides insights into the enzyme's catalytic mechanism and regulation by GDP-fucose.
Structure Fold.Des., 8, 2000
1I8L
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HUMAN B7-1/CTLA-4 CO-STIMULATORY COMPLEX
Descriptor:T LYMPHOCYTE ACTIVATION ANTIGEN CD80, CYTOTOXIC T-LYMPHOCYTE PROTEIN 4, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Stamper, C.C., Somers, W.S., Mosyak, L.
Deposit date:2001-03-14
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses.
Nature, 410, 2001
1XJD
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CRYSTAL STRUCTURE OF PKC-THETA COMPLEXED WITH STAUROSPORINE AT 2A RESOLUTION
Descriptor:Protein kinase C, theta type, STAUROSPORINE
Authors:Xu, Z.B.
Deposit date:2004-09-23
Release date:2004-10-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic domain crystal structure of protein kinase C-theta (PKCtheta)
J.Biol.Chem., 279, 2004