2ID5

Crystal Structure of the Lingo-1 Ectodomain

Summary for 2ID5

DescriptorLeucine rich repeat neuronal 6A, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE, ... (4 entities in total)
Functional Keywordscns-specific lrr-ig containing, ligand binding protein, membrane protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane ; Single-pass type I membrane protein  Q96FE5
Total number of polymer chains4
Total molecular weight228062.36
Authors
Mosyak, L.,Wood, A.,Dwyer, B.,Johnson, M.,Stahl, M.L.,Somers, W.S. (deposition date: 2006-09-14, release date: 2006-09-26, Last modification date: 2018-03-07)
Primary citation
Mosyak, L.,Wood, A.,Dwyer, B.,Buddha, M.,Johnson, M.,Aulabaugh, A.,Zhong, X.,Presman, E.,Benard, S.,Kelleher, K.,Wilhelm, J.,Stahl, M.L.,Kriz, R.,Gao, Y.,Cao, Z.,Ling, H.P.,Pangalos, M.N.,Walsh, F.S.,Somers, W.S.
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
J.Biol.Chem., 281:36378-36390, 2006
PubMed: 17005555 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M607314200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.698 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers60.2%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2id5
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Molmil generated image of 2id5
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Molmil generated image of 2id5
rotated about y axis by 90°