Author results

2QIU
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STRUCTURE OF HUMAN ARG-INSULIN
Descriptor:Insulin, ZINC ION
Authors:Sreekanth, R., Pattabhi, V., Rajan, S.S.
Deposit date:2007-07-05
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural interpretation of reduced insulin activity as seen in the crystal structure of human Arg-insulin
Biochimie, 90, 2008
2R34
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CRYSTAL STRUCTURE OF MN HUMAN ARG-INSULIN
Descriptor:Insulin, MANGANESE (II) ION, CHLORIDE ION
Authors:Sreekanth, R., Pattabhi, V., Rajan, S.S.
Deposit date:2007-08-29
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Metal induced structural changes observed in hexameric insulin
Int.J.Biol.Macromol., 44, 2009
2R35
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CRYSTAL STRUCTURE OF RB HUMAN ARG-INSULIN
Descriptor:Insulin, SODIUM ION, RUBIDIUM ION
Authors:Sreekanth, R., Pattabhi, V., Rajan, S.S.
Deposit date:2007-08-29
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Metal induced structural changes observed in hexameric insulin
Int.J.Biol.Macromol., 44, 2009
2R36
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CRYSTAL STRUCTURE OF NI HUMAN ARG-INSULIN
Descriptor:Insulin, NICKEL (II) ION, SODIUM ION, ...
Authors:Sreekanth, R., Pattabhi, V., Rajan, S.S.
Deposit date:2007-08-29
Release date:2008-09-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metal induced structural changes observed in hexameric insulin
Int.J.Biol.Macromol., 44, 2009
3M4Z
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CRYSTAL STRUCTURE OF B. SUBTILIS FERROCHELATASE WITH COBALT BOUND AT THE ACTIVE SITE
Descriptor:Ferrochelatase, COBALT (II) ION, MAGNESIUM ION, ...
Authors:Soderberg, C.A.G., Hansson, M.D., Sreekanth, R., Al-Karadaghi, S., Hansson, M.
Deposit date:2010-03-12
Release date:2010-11-10
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase
To be Published
4ITZ
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CRYSTAL STRUCTURE OF THE FK506 BINDING DOMAIN OF PLASMODIUM VIVAX FKBP35 IN COMPLEX WITH A TETRAPEPTIDE SUBSTRATE
Descriptor:70 kDa peptidylprolyl isomerase, substrate peptide, SULFATE ION
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2013-01-19
Release date:2013-03-20
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural insights into substrate binding by PvFKBP35, a peptidylprolyl cis-trans isomerase from the human malarial parasite Plasmodium vivax.
Eukaryot Cell, 12, 2013
3UQI
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CRYSTALLOGRAPHIC STRUCTURE OF FKBP12 FROM AEDES AEGYPTI
Descriptor:FKBP-type peptidyl-prolyl cis-trans isomerase, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, SULFATE ION
Authors:Sreekanth, R., Saw, K.Q., Yoon, H.S.
Deposit date:2011-11-20
Release date:2012-06-27
Method:X-RAY DIFFRACTION (1.302 Å)
Cite:High-resolution crystal structure of FKBP12 from Aedes aegypti.
Protein Sci., 21, 2012
4J4N
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CRYSTAL STRUCTURE OF FK506 BINDING DOMAIN OF PLASMODIUM FALCIPARUM FKBP35 IN COMPLEX WITH D44
Descriptor:FK506-binding protein (FKBP)-type peptidyl-propyl isomerase, N-(2-ethylphenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)acetamide
Authors:Sreekanth, R., Harikishore, A., Yoon, H.S.
Deposit date:2013-02-07
Release date:2013-09-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent.
Sci Rep, 3, 2013
4J4O
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CRYSTAL STRUCTURE OF FK506 BINDING DOMAIN OF PLASMODIUM VIVAX FKBP35 IN COMPLEX WITH D44
Descriptor:70 kDa peptidylprolyl isomerase, putative, N-(2-ethylphenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)acetamide, ...
Authors:Sreekanth, R., Harikishore, A., Yoon, H.S.
Deposit date:2013-02-07
Release date:2013-09-11
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent.
Sci Rep, 3, 2013
4JYS
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CRYSTAL STRUCTURE OF FKBP25 FROM PLASMODIUM VIVAX
Descriptor:Peptidyl-prolyl cis-trans isomerase, IMIDAZOLE, CHLORIDE ION
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2013-04-01
Release date:2014-02-12
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity
Proteins, 82, 2014
4PPI
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CRYSTAL STRUCTURE OF BCL-XL HEXAMER
Descriptor:Bcl-2-like protein 1, GLYCEROL
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2014-02-27
Release date:2015-03-04
Last modified:2015-06-10
Method:X-RAY DIFFRACTION (2.851 Å)
Cite:Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport
Sci Rep, 5, 2015
4QVE
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CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH BID BH3 DOMAIN
Descriptor:Bcl-2-like protein 1, Peptide from BH3-interacting domain death agonist, IMIDAZOLE
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2014-07-14
Release date:2015-06-10
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis
Proteins, 2015
4QVF
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CRYSTAL STRUCTURE OF BCL-XL IN COMPLEX WITH BIM BH3 DOMAIN
Descriptor:Bcl-2-like protein 1, Peptide from Bcl-2-like protein 11
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2014-07-15
Release date:2015-06-10
Method:X-RAY DIFFRACTION (1.531 Å)
Cite:Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis
Proteins, 2015
5Y41
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CRYSTAL STRUCTURE OF LIGAND-BOUND NURR1-LBD
Descriptor:Nuclear receptor subfamily 4 group A member 2, (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid, TRIETHYLENE GLYCOL, ...
Authors:Sreekanth, R., Lescar, J., Yoon, H.S.
Deposit date:2017-07-31
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Co-crystal structure and function of Nurr1 bound to the cyclopentenone prostaglandin A1
To be published
5YD6
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CRYSTAL STRUCTURE OF PG-BOUND NURR1-LBD
Descriptor:Nuclear receptor subfamily 4 group A member 2, (~{Z})-7-[(1~{R},5~{S})-2-oxidanylidene-5-[(~{E},3~{S})-3-oxidanyloct-1-enyl]cyclopent-3-en-1-yl]hept-5-enoic acid, MAGNESIUM ION
Authors:Sreekanth, R., Yoon, H.S.
Deposit date:2017-09-11
Release date:2019-03-27
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Structure of Nurr1 bound to cyclopentenone prostaglandin A2 and its mechanism of action in ameliorating dopaminergic neurodegeneration in Drosophila
To Be Published
5XGB
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CRYSTAL STRUCTURE OF THE PAS-GGDEF-EAL DOMAIN OF PA0861 FROM PSEUDOMONAS AERUGINOSA
Descriptor:Uncharacterized protein
Authors:Liu, C., Liew, C.W., Sreekanth, R., Lescar, J.
Deposit date:2017-04-13
Release date:2017-12-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.
J. Bacteriol., 200, 2018
5XGD
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CRYSTAL STRUCTURE OF THE PAS-GGDEF-EAL DOMAIN OF PA0861 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH GTP
Descriptor:Uncharacterized protein PA0861, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Liu, C., Liew, C.W., Sreekanth, R., Lescar, J.
Deposit date:2017-04-13
Release date:2017-12-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.
J. Bacteriol., 200, 2018
5XGE
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CRYSTAL STRUCTURE OF THE PAS-GGDEF-EAL DOMAIN OF PA0861 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH CYCLIC DI-GMP
Descriptor:Uncharacterized protein PA0861, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
Authors:Liu, C., Liew, C.W., Sreekanth, R., Lescar, J.
Deposit date:2017-04-13
Release date:2017-12-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Insights into Biofilm Dispersal Regulation from the Crystal Structure of the PAS-GGDEF-EAL Region of RbdA from Pseudomonas aeruginosa.
J. Bacteriol., 200, 2018
6AC9
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CRYSTAL STRUCTURE OF HUMAN VACCINIA-RELATED KINASE 1 (VRK1) IN COMPLEX WITH AMP-PNP
Descriptor:Serine/threonine-protein kinase VRK1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:Ngow, Y.S., Sreekanth, R., Yoon, H.S.
Deposit date:2018-07-25
Release date:2018-12-26
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structure of human vaccinia-related kinase 1 in complex with AMP-PNP, a non-hydrolyzable ATP analog.
Protein Sci., 28, 2019