Author results

2MDV
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NMR STRUCTURE OF BETA ALPHA ALPHA 38
Descriptor:Designed protein
Authors:Kier, B.L., Sheffler, W., Baker, D.
Deposit date:2013-09-18
Release date:2014-10-01
Method:SOLUTION NMR
Cite:Covalent Assembly of Homooligomeric Proteins Using Structure-templating Hubs
To be Published
2MDW
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NMR STRUCTURE OF A STRAND-SWAPPED DIMER OF THE WW DOMAIN
Descriptor:Designed protein
Authors:Kier, B.L., Sheffler, W., Baker, D.
Deposit date:2013-09-18
Release date:2014-10-01
Method:SOLUTION NMR
Cite:Covalent Assembly of Homooligomeric Proteins Using Structure-templating Hubs
To be Published
3VCD
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COMPUTATIONALLY DESIGNED SELF-ASSEMBLING OCTAHEDRAL CAGE PROTEIN, O333, CRYSTALLIZED IN SPACE GROUP R32
Descriptor:Propanediol utilization polyhedral body protein PduT, SULFATE ION, CHLORIDE ION
Authors:Sawaya, M.R., King, N.P., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2012-01-03
Release date:2012-06-06
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Computational design of self-assembling protein nanomaterials with atomic level accuracy.
Science, 336, 2012
4DCL
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COMPUTATIONALLY DESIGNED SELF-ASSEMBLING TETRAHEDRON PROTEIN, T308, CRYSTALLIZED IN SPACE GROUP F23
Descriptor:Putative acetyltransferase SACOL2570
Authors:Sawaya, M.R., King, N.P., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2012-01-17
Release date:2012-06-06
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Computational design of self-assembling protein nanomaterials with atomic level accuracy.
Science, 336, 2012
4DDF
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COMPUTATIONALLY DESIGNED SELF-ASSEMBLING OCTAHEDRAL CAGE PROTEIN, O333, CRYSTALLIZED IN SPACE GROUP P4
Descriptor:Propanediol utilization polyhedral body protein PduT, SULFATE ION, CHLORIDE ION
Authors:Sawaya, M.R., King, N.P., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2012-01-18
Release date:2012-06-06
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Computational design of self-assembling protein nanomaterials with atomic level accuracy.
Science, 336, 2012
4EGG
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COMPUTATIONALLY DESIGNED SELF-ASSEMBLING TETRAHEDRON PROTEIN, T310
Descriptor:Putative acetyltransferase SACOL2570, GLYCEROL
Authors:Sawaya, M.R., King, N.P., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2012-03-30
Release date:2012-05-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Computational design of self-assembling protein nanomaterials with atomic level accuracy.
Science, 336, 2012
4NWN
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T32-28
Descriptor:Uncharacterized protein, Propanediol utilization: polyhedral bodies pduT
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWO
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T33-15
Descriptor:Molybdenum cofactor biosynthesis protein MogA, Chorismate mutase AroH, CALCIUM ION
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWP
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE, T33-21, CRYSTALLIZED IN SPACE GROUP R32
Descriptor:Putative uncharacterized protein, Uncharacterized protein, SULFATE ION, ...
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWQ
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE, T33-21, CRYSTALLIZED IN SPACE GROUP F4132
Descriptor:Putative uncharacterized protein PH0671, Uncharacterized protein, SULFATE ION
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
4NWR
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COMPUTATIONALLY DESIGNED TWO-COMPONENT SELF-ASSEMBLING TETRAHEDRAL CAGE T33-28
Descriptor:integron gene cassette protein, Macrophage migration inhibitory factor-like protein
Authors:McNamara, D.E., King, N.P., Bale, J.B., Sheffler, W., Baker, D., Yeates, T.O.
Deposit date:2013-12-06
Release date:2014-05-28
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Accurate design of co-assembling multi-component protein nanomaterials.
Nature, 510, 2014
5IM4
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CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I52-32
Descriptor:6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA
Authors:Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
Deposit date:2016-03-05
Release date:2016-07-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
5IM5
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CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I53-40
Descriptor:Designed Riboflavin synthase, Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase
Authors:Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
Deposit date:2016-03-05
Release date:2016-07-27
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (3.699 Å)
Cite:Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
5IM6
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CRYSTAL STRUCTURE OF DESIGNED TWO-COMPONENT SELF-ASSEMBLING ICOSAHEDRAL CAGE I32-28
Descriptor:Designed self-assembling icosahedral cage I32-28 trimeric subunit, Designed self-assembling icosahedral cage I32-28 dimeric subunit
Authors:Liu, Y.A., Cascio, D., Sawaya, M.R., Bale, J.B., Collazo, M.J., Thomas, C., Sheffler, W., King, N.P., Baker, D., Yeates, T.O.
Deposit date:2016-03-05
Release date:2016-07-27
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (5.588 Å)
Cite:Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
6D0T
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DE NOVO DESIGN OF A FLUORESCENCE-ACTIVATING BETA BARREL - BB1
Descriptor:BB1
Authors:Dou, J., Vorobieva, A.A., Sheffler, W., Doyle, L.A., Park, H., Bick, M.J., Mao, B., Foight, G.W., Lee, M., Carter, L., Sankaran, B., Ovchinnikov, S., Marcos, E., Huang, P., Vaughan, J.C., Stoddard, B.L., Baker, D.
Deposit date:2018-04-10
Release date:2018-09-19
Last modified:2018-10-17
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:De novo design of a fluorescence-activating beta-barrel.
Nature, 561, 2018
6B85
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CRYSTAL STRUCTURE OF TRANSMEMBRANE PROTEIN TMHC4_R
Descriptor:TMHC4_R
Authors:Lu, P., DiMaio, F., Min, D., Bowie, J., Wei, K.Y., Baker, D.
Deposit date:2017-10-05
Release date:2018-03-14
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (3.889 Å)
Cite:Accurate computational design of multipass transmembrane proteins.
Science, 359, 2018
6B87
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CRYSTAL STRUCTURE OF TRANSMEMBRANE PROTEIN TMHC2_E
Descriptor:TMHC2_E
Authors:Lu, P., DiMaio, F., Min, D., Wei, K.Y., Bowie, J., Baker, D.
Deposit date:2017-10-05
Release date:2018-03-14
Method:X-RAY DIFFRACTION (2.947 Å)
Cite:Accurate computational design of multipass transmembrane proteins.
Science, 359, 2018
4GMR
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR266.
Descriptor:OR266 DE NOVO PROTEIN, NITRATE ION
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Mao, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-16
Release date:2012-08-29
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.377 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
4GPM
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR264.
Descriptor:Engineered Protein OR264
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Maglaqui, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-08-21
Release date:2012-09-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
4HB5
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR267.
Descriptor:Engineered Protein
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Maglaqui, M., Xiao, R., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-09-27
Release date:2012-10-10
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
4HXT
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CRYSTAL STRUCTURE OF ENGINEERED PROTEIN. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET OR329
Descriptor:De Novo Protein OR329
Authors:Vorobiev, S., Su, M., Parmeggiani, F., Seetharaman, J., Huang, P.-S., Maglaqui, M., Xiao, X., Lee, D., Everett, J.K., Acton, T.B., Baker, D., Montelione, G.T., Tong, L., Hunt, J.F., Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-11-12
Release date:2012-11-21
Last modified:2017-04-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
NAT.CHEM., 9, 2017
5EIL
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COMPUTATIONAL DESIGN OF A HIGH-AFFINITY METALLOPROTEIN HOMOTRIMER CONTAINING A METAL CHELATING NON-CANONICAL AMINO ACID
Descriptor:TRI-05, FE (III) ION
Authors:Sankaran, B., Zwart, P.H., Mills, J.H., Pereira, J.H., Baker, D.
Deposit date:2015-10-30
Release date:2016-11-16
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Computational design of a homotrimeric metalloprotein with a trisbipyridyl core.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5HRY
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COMPUTATIONALLY DESIGNED CYCLIC DIMER ANK3C2_1
Descriptor:ank3C2_1
Authors:Cascio, D., McNamara, D.E., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
5HRZ
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COMPUTATIONALLY DESIGNED TRIMER 1NA0C3_3
Descriptor:TPR domain protein 1na0C3_3
Authors:Cascio, D., McNamara, D.E., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
5HS0
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COMPUTATIONALLY DESIGNED CYCLIC TETRAMER ANK1C4_7
Descriptor:Ankyrin domain protein ank1C4_7, SULFATE ION, GLYCEROL
Authors:McNamara, D.E., Cascio, D., Fallas, J.A., Baker, D., Yeates, T.O.
Deposit date:2016-01-24
Release date:2017-04-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
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