Author results

5H23
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CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS CAPSID PROTEIN
分子名称:Capsid Protein, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ...
著者Sharma, R., Kesari, P., Tomar, S., Kumar, P.
登録日2016-10-14
公開日2018-03-14
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-function insights into chikungunya virus capsid protein: Small molecules targeting capsid hydrophobic pocket.
Virology, 515, 2018
2MYI
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SOLUTION STRUCTURE OF CRC FROM P. SYRINGAE LZ4W
分子名称:Exodeoxyribonuclease III
著者Deshmukh, M.V., Sharma, R.
登録日2015-01-25
公開日2016-01-27
実験手法SOLUTION NMR
主引用文献Crc binds RNA independent of Hfq
To be Published
5FTW
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CRYSTAL STRUCTURE OF GLUTAMATE O-METHYLTRANSFERASE IN COMPLEX WITH S- ADENOSYL-L-HOMOCYSTEINE (SAH) FROM BACILLUS SUBTILIS
分子名称:CHEMOTAXIS PROTEIN METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者Sharma, R., Dhindwal, S., Batra, M., Aggarwal, M., Kumar, P., Tomar, S.
登録日2016-01-18
公開日2016-10-05
最終更新日2016-12-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Pentapeptide-Independent Chemotaxis Receptor Methyltransferase (Cher) Reveals Idiosyncratic Structural Determinants for Receptor Recognition.
J.Struct.Biol., 196, 2016
3NOE
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CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM PSEUDOMONAS AERUGINOSA
分子名称:Dihydrodipicolinate synthase, S-1,2-PROPANEDIOL
著者Kaur, N., Kumar, S., Singh, N., Gautam, A., Sharma, R., Sharma, S., Tewari, R., Singh, T.P.
登録日2010-06-25
公開日2010-07-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal Structure of Dihydrodipicolinate synthase from Pseudomonas aeruginosa
To be Published
3PS7
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BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURE DETERMINATION OF DIHYDRODIPICOLINATE SYNTHASE FROM PSEUDOMONAS AERUGINOSA
分子名称:Dihydrodipicolinate synthase, S-1,2-PROPANEDIOL
著者Kaur, N., Gautam, A., Kumar, S., Singh, A., Singh, N., Sharma, S., Sharma, R., Tewari, R., Singh, T.P.
登録日2010-12-01
公開日2010-12-15
最終更新日2011-09-07
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa
Int.J.Biol.Macromol., 48, 2011
3PUO
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CRYSTAL STRUCTURE OF DIHYDRODIPICOLINATE SYNTHASE FROM PSEUDOMONAS AERUGINOSA(PSDHDPS)COMPLEXED WITH L-LYSINE AT 2.65A RESOLUTION
分子名称:Dihydrodipicolinate synthase, LYSINE, GLYCEROL
著者Kaur, N., Kumar, M., Kumar, S., Gautam, A., Sinha, M., Kaur, P., Sharma, S., Sharma, R., Tewari, R., Singh, T.P.
登録日2010-12-06
公開日2010-12-29
最終更新日2011-09-07
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Biochemical studies and crystal structure determination of dihydrodipicolinate synthase from Pseudomonas aeruginosa
Int.J.Biol.Macromol., 48, 2011
1YNY
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MOLECULAR STRUCTURE OF D-HYDANTOINASE FROM A BACILLUS SP. AR9: EVIDENCE FOR MERCURY INHIBITION
分子名称:D-Hydantoinase, MANGANESE (II) ION
著者Radha Kishan, K.V., Vohra, R.M., Ganeshan, K., Agrawal, V., Sharma, V.M., Sharma, R.
登録日2005-01-26
公開日2005-03-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular structure of D-hydantoinase from Bacillus sp. AR9: evidence for mercury inhibition.
J.Mol.Biol., 347, 2005
3ZJT
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TERNARY COMPLEX OF E.COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU)574 AND THE BENZOXABOROLE AN3017 IN THE EDITING CONFORMATION
分子名称:LEUCYL-TRNA SYNTHETASE, TRNALEU5 UAA ISOACCEPTOR, MAGNESIUM ION
著者Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
登録日2013-01-18
公開日2013-04-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
3ZJU
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TERNARY COMPLEX OF E .COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN3016 IN THE EDITING CONFORMATION
分子名称:LEUCYL-TRNA SYNTHETASE, TRNALEU5 UAA ISOACCEPTOR, MAGNESIUM ION
著者Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
登録日2013-01-18
公開日2013-04-17
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
3ZJV
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TERNARY COMPLEX OF E .COLI LEUCYL-TRNA SYNTHETASE, TRNA(LEU) AND THE BENZOXABOROLE AN3213 IN THE EDITING CONFORMATION
分子名称:LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR
著者Cusack, S., Palencia, A., Crepin, T., Hernandez, V., Akama, T., Baker, S.J., Bu, W., Feng, L., Freund, Y.R., Liu, L., Meewan, M., Mohan, M., Mao, W., Rock, F.L., Sexton, H., Sheoran, A., Zhang, Y., Zhang, Y., Zhou, Y., Nieman, J.A., Anugula, M.R., Keramane, E.M., Savariraj, K., Reddy, D.S., Sharma, R., Subedi, R., Singh, R., OLeary, A., Simon, N.L., DeMarsh, P.L., Mushtaq, S., Warner, M., Livermore, D.M., Alley, M.R.K., Plattner, J.J.
登録日2013-01-18
公開日2013-04-17
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57, 2013
4LS9
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STRUCTURE OF MYCOBACTERIAL NRNA HOMOLOG REVEALS MULTIFUNCTIONAL NUCLEASE ACTIVITIES
分子名称:DHH family protein, MANGANESE (II) ION, GLYCEROL
著者Kumar, D., Srivastav, R., Grover, A., Manjasetty, B.A., Sharma, R., Taneja, B.
登録日2013-07-22
公開日2014-07-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unique subunit packing in mycobacterial nanoRNase leads to alternate substrate recognitions in DHH phosphodiesterases
Nucleic Acids Res., 42, 2014
2JWG
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STRUCTURE OF A GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED DOMAIN FROM A TRYPANOSOME VARIANT SURFACE GLYCOPROTEIN
分子名称:Variant surface glycoprotein ILTAT 1.24
著者Jones, N.G., Nietlispach, D., Sharma, R., Burke, D.F., Eyres, I., Mues, M., Mott, H.R., Carrington, M.
登録日2007-10-12
公開日2007-11-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
J.Biol.Chem., 283, 2008
2JWH
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STRUCTURE OF A GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED DOMAIN FROM A TRYPANOSOME VARIANT SURFACE GLYCOPROTEIN
分子名称:Variant surface glycoprotein ILTAT 1.24
著者Jones, N.G., Nietlispach, D., Sharma, R., Burke, D.F., Eyres, I., Mues, M., Mott, H.R., Carrington, M.
登録日2007-10-12
公開日2007-11-13
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
J.Biol.Chem., 283, 2008
4A7G
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STRUCTURE OF HUMAN I113T SOD1 MUTANT COMPLEXED WITH 4-METHYLPIPERAZIN- 1-YL)QUINAZOLINE IN THE P21 SPACE GROUP.
分子名称:SUPEROXIDE DISMUTASE [CU-ZN], SULFATE ION, 4-(4-METHYLPIPERAZIN-1-YL)QUINAZOLINE, ...
著者Wright, G.S.A., Kershaw, N.M., Sharma, R., Antonyuk, S.V., Strange, R.W., Berry, N.G., O'Neil, P.M., Hasnain, S.S.
登録日2011-11-14
公開日2012-10-24
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献X-ray crystallography and computational docking for the detection and development of protein-ligand interactions.
Curr. Med. Chem., 20, 2013
5XQL
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CRYSTAL STRUCTURE OF A PSEUDOMONAS AERUGINOSA TRANSCRIPTIONAL REGULATOR
分子名称:Multidrug-efflux transporter 1 regulator, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one)
著者Raju, H., Sharma, R.
登録日2017-06-07
公開日2017-06-28
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.494 Å)
主引用文献Crystal structure of BrlR with c-di-GMP
Biochem. Biophys. Res. Commun., 490, 2017
6BNH
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SOLUTION NMR STRUCTURES OF BRD4 ET DOMAIN WITH JMJD6 PEPTIDE
分子名称:Bromodomain-containing protein 4, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
著者Konuma, T., Yu, D., Zhao, C., Ju, Y., Sharma, R., Ren, C., Zhang, Q., Zhou, M.-M., Zeng, L.
登録日2017-11-16
公開日2017-12-20
実験手法SOLUTION NMR
主引用文献Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4.
Sci Rep, 7, 2017
5YBC
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X-RAY STRUCTURE OF NATIVE ETS-DOMAIN DOMAIN OF ERGP55
分子名称:Transcriptional regulator ERG, GLYCEROL
著者Saxena, A.K., Gangwar, S.P.
登録日2017-09-04
公開日2018-09-19
最終更新日2018-10-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018
5YBD
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X-RAY STRUCTURE OF ETS DOMAIN OF ERGP55 IN COMPLEX WITH E74DNA
分子名称:Transcriptional regulator ERG, DNA (5'-D(P*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3')
著者Saxena, A.K., Gangwar, S.P.
登録日2017-09-04
公開日2018-11-14
実験手法X-RAY DIFFRACTION (2.769 Å)
主引用文献Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence
Acta Crystallogr F Struct Biol Commun, 74, 2018
5E0N
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CRYSTAL STRUCTURE OF MSMEG_3139, A MONOFUNCTIONAL ENOYL COA ISOMERASE FROM M.SMEGMATIS
分子名称:Enoyl-CoA hydratase/isomerase
著者Priyadarshan, K., Haque, A.S., Anandakrishnan, M., Sankaranarayanan, R.
登録日2015-09-29
公開日2016-02-03
実験手法X-RAY DIFFRACTION (2.061 Å)
主引用文献Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase.
Chem.Biol., 22, 2015
5YC9
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CRYSTAL STRUCTURE OF A PSEUDOMONAS AERUGINOSA TRANSCRIPTIONAL REGULATOR
分子名称:C-di-GMP-binding multidrug transporter transcriptional regulator BrlR
著者Harikiran, R., Rohan, S.
登録日2017-09-07
公開日2019-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a Pseudomonas aeruginosa transcriptional regulator
To Be Published
3O0J
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PDE4B IN COMPLEX WITH LIGAND AN2898
分子名称:cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ZINC ION, MAGNESIUM ION, ...
著者Alley, M.R.K., Zhou, Y.
登録日2010-07-19
公開日2011-08-10
最終更新日2013-01-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Boron-based phosphodiesterase inhibitors show novel binding of boron to PDE4 bimetal center.
Febs Lett., 586, 2012
4Z0M
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ECHA5 MYCOBACTERIUM TUBERCULOSIS
分子名称:Enoyl-CoA hydratase
著者Chaudhary, S., Gokhale, R.S.
登録日2015-03-26
公開日2016-02-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase
Chem.Biol., 22, 2015
2Q1J
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THE DISCOVERY OF GLYCINE AND RELATED AMINO ACID-BASED FACTOR XA INHIBITORS
分子名称:Activated factor Xa heavy chain (EC 3.4.21.6), Factor X light chain (EC 3.4.21.6), CALCIUM ION, ...
著者Kohrt, J.T., Filipski, K.J., Cody, W.L., Bigge, C.F., Zhang, E., Finzel, B.C.
登録日2007-05-24
公開日2007-08-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Discovery of Glycine and Related Amino Acid-Based Factor Xa Inhibitors
BIOORG.MED.CHEM., 14, 2006
3GI3
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CRYSTAL STRUCTURE OF A N-PHENYL-N'-NAPHTHYLUREA ANALOG IN COMPLEX WITH P38 MAP KINASE
分子名称:Mitogen-activated protein kinase 14, N-{5-tert-butyl-2-methoxy-3-[({4-[6-(morpholin-4-ylmethyl)pyridin-3-yl]naphthalen-1-yl}carbamoyl)amino]phenyl}methanesulfonamide
著者Qian, K.C.
登録日2009-03-05
公開日2009-10-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Discovery and characterization of the N-phenyl-N'-naphthylurea class of p38 kinase inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
3OTQ
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SOLUBLE EPOXIDE HYDROLASE IN COMPLEX WITH PYRAZOLE ANTAGONIST
分子名称:Epoxide hydrolase 2, N-[4-(5-ethyl-3-pyridin-3-yl-1H-pyrazol-1-yl)phenyl]pyridine-3-carboxamide
著者Farrow, N.A.
登録日2010-09-13
公開日2010-10-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain.
Bioorg.Med.Chem.Lett., 20, 2010
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