9C6V
Crystal Structure of a single chain trimer composed of HLA-B*39:06 Y84C variant, beta-2microglobulin, and NRVMLPKAA peptide from NLRP2 (1 molecule/asymmetric unit)
Summary for 9C6V
Entry DOI | 10.2210/pdb9c6v/pdb |
Related | 9C6W 9C6X |
Descriptor | NACHT, LRR and PYD domains-containing protein 2,Beta-2-microglobulin,MHC class I antigen, 1,2-ETHANEDIOL, GLYCEROL, ... (5 entities in total) |
Functional Keywords | hla class i histocompatibility antigen, b-39 alpha chain, beta-2-microglobulin, nlrp2, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 47102.16 |
Authors | Sharma, R.,Amdare, N.P.,Celikgil, A.,Garforth, S.J.,DiLorenzo, T.P.,Almo, S.C.,Ghosh, A. (deposition date: 2024-06-09, release date: 2024-09-04) |
Primary citation | Sharma, R.,Amdare, N.P.,Ghosh, A.,Schloss, J.,Sidney, J.,Garforth, S.J.,Lopez, Y.,Celikgil, A.,Sette, A.,Almo, S.C.,DiLorenzo, T.P. Structural and biochemical analysis of highly similar HLA-B allotypes differentially associated with type 1 diabetes. J.Biol.Chem., :107702-107702, 2024 Cited by PubMed: 39173948DOI: 10.1016/j.jbc.2024.107702 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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