Author results

2VNA
  • Download 2vna
  • View 2vna
Molmil generated image of 2vna
STRUCTURE OF HUMAN ZINC-BINDING ALCOHOL DEHYDROGENASE 1 (ZADH1)
分子名称:PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Shafqat, N., Kavanagh, K., Pike, A.C.W., Muniz, J.R.C., Pilka, E., Roos, A.K., Picaud, S., Johansson, C., Smee, C., Fedorov, O., Kochan, G., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., von Delft, F., Opperman, U.
登録日2008-02-01
公開日2009-02-17
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure of Human Zinc-Binding Alcohol Dehydrogenase 1 (Zadh1)
To be Published
2W4Q
  • Download 2w4q
  • View 2w4q
Molmil generated image of 2w4q
CRYSTAL STRUCTURE OF HUMAN ZINC-BINDING ALCOHOL DEHYDROGENASE 1 (ZADH1) IN TERNARY COMPLEX WITH NADP AND 18BETA-GLYCYRRHETINIC ACID
分子名称:PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID, ...
著者Shafqat, N., Yue, W.W., Ugochukwu, E., Picaud, S., Niesen, F., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2008-11-30
公開日2009-01-20
最終更新日2013-12-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Human Zinc-Binding Alcohol Dehydrogenase 1
To be Published
2W98
  • Download 2w98
  • View 2w98
Molmil generated image of 2w98
CRYSTAL STRUCTURE OF HUMAN ZINC-BINDING ALCOHOL DEHYDROGENASE 1 (ZADH1) IN TERNARY COMPLEX WITH NADP AND PHENYLBUTAZONE
分子名称:PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, ...
著者Shafqat, N., Yue, W.W., Muniz, J., Picaud, S., Niesen, F., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-01-22
公開日2009-04-07
最終更新日2013-12-04
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of Human Zinc-Binding Alcohol Dehydrogenase 1
To be Published
2WEK
  • Download 2wek
  • View 2wek
Molmil generated image of 2wek
CRYSTAL STRUCTURE OF THE HUMAN MGC45594 GENE PRODUCT IN COMPLEX WITH DICLOFENAC
分子名称:ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ...
著者Shafqat, N., Yue, W.W., Ugochukwu, E., Niesen, F., Smee, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-03-31
公開日2009-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Human Mgc45594 Gene Product in Complex with Diclofenac
To be Published
2X1H
  • Download 2x1h
  • View 2x1h
Molmil generated image of 2x1h
CRYSTAL STRUCTURE OF THE HUMAN MGC45594 GENE PRODUCT IN COMPLEX WITH RALOXIFENE
分子名称:ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Shafqat, N., Yue, W.W., Pike, A.C.W., Niesen, F., Ugochukwu, E., Krojer, T., Chaikuad, A., Smee, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-12-24
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the Human Mgc45594 Gene Product in Complex with Raloxifene
To be Published
2X7H
  • Download 2x7h
  • View 2x7h
Molmil generated image of 2x7h
CRYSTAL STRUCTURE OF THE HUMAN MGC45594 GENE PRODUCT IN COMPLEX WITH FENOPROFEN
分子名称:ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, FENOPROFEN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Shafqat, N., Yue, W.W., Ugochukwu, E., Niesen, F., Vollmar, M., Chaikuad, A., Pike, A.C.W., von Delft, F., Smee, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2010-02-26
公開日2010-12-08
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Human Mgc45594 Gene Product in Complex with Fenoprofen
To be Published
2P8U
  • Download 2p8u
  • View 2p8u
Molmil generated image of 2p8u
CRYSTAL STRUCTURE OF HUMAN 3-HYDROXY-3-METHYLGLUTARYL COA SYNTHASE I
分子名称:Hydroxymethylglutaryl-CoA synthase, cytoplasmic, COENZYME A, ...
著者Turnbull, A., Shafqat, N., Salah, E., Niesen, F.H., Burgess, N., Bunkoczi, G., Debreczeni, J., Pike, A.C.W., Umeano, C., Gorrec, F., von Delft, F., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-03-23
公開日2007-04-03
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
J.Mol.Biol., 398, 2010
2WH5
  • Download 2wh5
  • View 2wh5
Molmil generated image of 2wh5
CRYSTAL STRUCTURE OF HUMAN ACYL-COA BINDING DOMAIN 4 COMPLEXED WITH STEAROYL-COA
分子名称:ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 4, STEARIC ACID, STEAROYL-COENZYME A, ...
著者Yue, W.W., Shafqat, N., Ugochukwu, E., Savitsky, P., Johansson, C., Salah, E., Roos, A.K., Chaikuad, A., von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-04-30
公開日2009-07-28
最終更新日2013-09-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Human Acyl-Coa Binding Domain 4
To be Published
2WYA
  • Download 2wya
  • View 2wya
Molmil generated image of 2wya
CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL 3-HYDROXY-3-METHYLGLUTARYL- COENZYME A SYNTHASE 2 (HMGCS2)
分子名称:HYDROXYMETHYLGLUTARYL-COA SYNTHASE, MITOCHONDRIAL, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, ...
著者Yue, W.W., Shafqat, N., Savitsky, P., Roos, A.K., Cooper, C., Murray, J.W., von Delft, F., Arrowsmith, C., Wikstrom, M., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-11-13
公開日2009-11-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structures of Human Hmg-Coa Synthase Isoforms Provide Insights Into Inherited Ketogenesis Disorders and Inhibitor Design.
J.Mol.Biol., 398, 2010
2YDX
  • Download 2ydx
  • View 2ydx
Molmil generated image of 2ydx
CRYSTAL STRUCTURE OF HUMAN S-ADENOSYLMETHIONINE SYNTHETASE 2, BETA SUBUNIT
分子名称:METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA, RESVERATROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Muniz, J.R.C., Shafqat, N., Pike, A.C.W., Yue, W.W., Vollmar, M., Papagriogriou, V., Roos, A., Gileadi, O., von Delft, F., Kavanagh, K.L., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
登録日2011-03-25
公開日2011-04-27
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insight Into S-Adenosylmethionine Biosynthesis from the Crystal Structures of the Human Methionine Adenosyltransferase Catalytic and Regulatory Subunits.
Biochem.J., 452, 2013
2YDY
  • Download 2ydy
  • View 2ydy
Molmil generated image of 2ydy
CRYSTAL STRUCTURE OF HUMAN S-ADENOSYLMETHIONINE SYNTHETASE 2, BETA SUBUNIT IN ORTHORHOMBIC CRYSTAL FORM
分子名称:METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA, SULFATE ION, CHLORIDE ION
著者Yue, W.W., Shafqat, N., Muniz, J.R.C., Pike, A.C.W., Chaikuad, A., Allerston, C.K., Gileadi, O., von Delft, F., Kavanagh, K.L., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
登録日2011-03-25
公開日2011-04-20
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Insight Into S-Adenosylmethionine Biosynthesis from the Crystal Structures of the Human Methionine Adenosyltransferase Catalytic and Regulatory Subunits.
Biochem.J., 452, 2013
2VSV
  • Download 2vsv
  • View 2vsv
Molmil generated image of 2vsv
CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN RHOPHILIN-2
分子名称:RHOPHILIN-2
著者Pike, A.C.W., Kochan, G., Sun, Z., Shafqat, N., Pilka, E.S., Roos, A., Elkins, J., Burgess-Brown, N., Murray, J.W., von Delft, F., Wikstrom, M., Edwards, A., Arrowsmith, C.H., Bountra, C., Oppermann, U.
登録日2008-04-29
公開日2008-07-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal Structure of the Pdz Domain of Human Rhophilin-2
To be Published
2WM8
  • Download 2wm8
  • View 2wm8
Molmil generated image of 2wm8
CRYSTAL STRUCTURE OF HUMAN MAGNESIUM-DEPENDENT PHOSPHATASE 1 OF THE HALOACID DEHALOGENASE SUPERFAMILY (MGC5987)
分子名称:MAGNESIUM-DEPENDENT PHOSPHATASE 1, 1,2-ETHANEDIOL
著者Yue, W.W., Shafqat, N., Pike, A.C.W., Chaikuad, A., Bray, J.E., Pilka, E.W., Burgess-Brown, N., Hapka, E., Filippakopoulos, P., von Delft, F., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-06-30
公開日2009-07-28
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Human Magnesium-Dependent Phosphatase 1 of the Haloacid Dehalogenase Superfamily (Mgc5987)
To be Published
1ZBQ
  • Download 1zbq
  • View 1zbq
Molmil generated image of 1zbq
CRYSTAL STRUCTURE OF HUMAN 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 4 IN COMPLEX WITH NAD
分子名称:17-beta-hydroxysteroid dehydrogenase 4, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Lukacik, P., Shafqat, N., Kavanagh, K., Bray, J., von Delft, F., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-04-08
公開日2005-04-26
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystal Structure Of Human 17-Beta-Hydroxysteroid Dehydrogenase Type 4 In Complex With NAD
To be Published
1ZSY
  • Download 1zsy
  • View 1zsy
Molmil generated image of 1zsy
THE STRUCTURE OF HUMAN MITOCHONDRIAL 2-ENOYL THIOESTER REDUCTASE (CGI-63)
分子名称:MITOCHONDRIAL 2-ENOYL THIOESTER REDUCTASE, SULFATE ION, GLYCEROL
著者Lukacik, P., Shafqat, N., Kavanagh, K.L., Johansson, C., Smee, C., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-05-25
公開日2005-06-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The structure of human mitochondrial 2-enoyl thioester reductase (CGI-63)
To be Published
2C0C
  • Download 2c0c
  • View 2c0c
Molmil generated image of 2c0c
STRUCTURE OF THE MGC45594 GENE PRODUCT
分子名称:ZINC BINDING ALCOHOL DEHYDROGENASE, DOMAIN CONTAINING 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Bunkoczi, G., Shafqat, N., Guo, K., Smee, C., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Gileadi, O., von Delft, F., Oppermann, U.
登録日2005-08-30
公開日2005-09-12
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Structure of Mgc45594 Gene Product
To be Published
2DFD
  • Download 2dfd
  • View 2dfd
Molmil generated image of 2dfd
CRYSTAL STRUCTURE OF HUMAN MALATE DEHYDROGENASE TYPE 2
分子名称:Malate dehydrogenase, D-MALATE, CHLORIDE ION, ...
著者Ugochukwu, E., Shafqat, N., Rojkova, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-02-28
公開日2006-03-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Human Malate Dehydrogenase Type 2
To be Published
2F6Q
  • Download 2f6q
  • View 2f6q
Molmil generated image of 2f6q
THE CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL DELTA3, DELTA2 ENOYL COA ISOMERASE (PECI)
分子名称:Peroxisomal 3,2-trans-enoyl-CoA isomerase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Turnbull, A., Lukacik, P., Shafqat, N., Smee, C., Berridge, G., Guo, K., von Delft, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Gileadi, O., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-11-29
公開日2005-12-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of human peroxisomal delta3, delta2 enoyl CoA isomerase (PECI)
To be Published
2H5G
  • Download 2h5g
  • View 2h5g
Molmil generated image of 2h5g
CRYSTAL STRUCTURE OF HUMAN PYRROLINE-5-CARBOXYLATE SYNTHETASE
分子名称:Delta 1-pyrroline-5-carboxylate synthetase, SULFATE ION
著者Papagrigoriou, E., Shafqat, N., Turnbull, A.P., Berridge, G., Hozjan, V., Kavanagh, K., Gileadi, O., Smee, C., Bray, J., Gorrec, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-05-26
公開日2006-06-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of human pyrroline-5-carboxylate synthetase
To be published
2J8Z
  • Download 2j8z
  • View 2j8z
Molmil generated image of 2j8z
CRYSTAL STRUCTURE OF HUMAN P53 INDUCIBLE OXIDOREDUCTASE (TP53I3,PIG3)
分子名称:QUINONE OXIDOREDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Pike, A.C.W., Shafqat, N., Debreczeni, J., Johansson, C., Haroniti, A., Gileadi, O., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., von Delft, F., Porte, S., Fita, I., Pares, J., Pares, X., Oppermann, U.
登録日2006-10-31
公開日2006-11-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Three-Dimensional Structure and Enzymatic Function of Proapoptotic Human P53-Inducible Quinone Oxidoreductase Pig3.
J.Biol.Chem., 284, 2009
2O23
  • Download 2o23
  • View 2o23
Molmil generated image of 2o23
THE STRUCTURE OF WILD-TYPE HUMAN HADH2 (17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 10) BOUND TO NAD+ AT 1.2 A
分子名称:HADH2 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL
著者Kavanagh, K.L., Shafqat, N., Scholer, K., Debreczeni, J., Zschocke, J., von Delft, F., Weigelt, J., Arrowsmith, C., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-11-29
公開日2006-12-12
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The structure of wild-type human HADH2 (17beta-hydroxysteroid dehydrogenase type 10) bound to NAD+ at 1.2 A
To be Published
2OBV
  • Download 2obv
  • View 2obv
Molmil generated image of 2obv
CRYSTAL STRUCTURE OF THE HUMAN S-ADENOSYLMETHIONINE SYNTHETASE 1 IN COMPLEX WITH THE PRODUCT
分子名称:S-adenosylmethionine synthetase isoform type-1, SODIUM ION, S-ADENOSYLMETHIONINE, ...
著者Pilka, E.S., Shafqat, N., Kavanagh, K.L., Cooper, C., Hozjan, V., Turnbull, A., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-12-20
公開日2007-01-02
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with the product.
To be Published
2OBY
  • Download 2oby
  • View 2oby
Molmil generated image of 2oby
CRYSTAL STRUCTURE OF HUMAN P53 INDUCIBLE OXIDOREDUCTASE (TP53I3,PIG3)
分子名称:Putative quinone oxidoreductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Porte, S., Valencia, E., Farres, J., Fita, I., Pike, A.C.W., Shafqat, N., Debreczeni, J., Johansson, C., Haroniti, A., Gileadi, O., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., von Delft, F., Oppermann, U., Pares, X.
登録日2006-12-20
公開日2007-01-30
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of human P53 inducible oxidoreductase (TP53I3, PIG3)
To be Published
2P02
  • Download 2p02
  • View 2p02
Molmil generated image of 2p02
CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF HUMAN S-ADENOSYLMETHIONINE SYNTHETASE 2
分子名称:S-adenosylmethionine synthetase isoform type-2, CHLORIDE ION, S-ADENOSYLMETHIONINE
著者Papagrigoriou, E., Shafqat, N., Rojkova, A., Niessen, F.H., Kavanagh, K.L., von Delft, F., Gorrec, F., Ugochukwu, E., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-02-28
公開日2007-03-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.21 Å)
主引用文献Crystal structure of the alpha subunit of human S-adenosylmethionine synthetase 2
To be Published
2VSP
  • Download 2vsp
  • View 2vsp
Molmil generated image of 2vsp
CRYSTAL STRUCTURE OF THE FOURTH PDZ DOMAIN OF PDZ DOMAIN-CONTAINING PROTEIN 1
分子名称:PDZ DOMAIN-CONTAINING PROTEIN 1
著者Yue, W.W., Shafqat, N., Pilka, E.S., Johansson, C., Murray, J.W., Elkins, J., Roos, A., Cooper, C., Phillips, C., Salah, E., von Delft, F., Doyle, D., Edwards, A., Wikstrom, M., Arrowsmith, C., Bountra, C., Oppermann, U.
登録日2008-04-28
公開日2009-03-03
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal Structure of the Fourth Pdz Domain of Pdz Domain-Containing Protein 1
To be Published
<12>