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2WEK

Crystal structure of the human MGC45594 gene product in complex with diclofenac

Summary for 2WEK
Entry DOI10.2210/pdb2wek/pdb
Related2C0C
DescriptorZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[2,6-DICHLOROPHENYL)AMINO]BENZENEACETIC ACID, ... (7 entities in total)
Functional Keywordsnadp, oxidoreductase, drug metabolism, medium-chain dehydrogenase/reductase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationPeroxisome (By similarity): Q8N4Q0
Total number of polymer chains2
Total formula weight77114.23
Authors
Shafqat, N.,Yue, W.W.,Ugochukwu, E.,Niesen, F.,Smee, C.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2009-03-31, release date: 2009-12-15, Last modification date: 2023-12-13)
Primary citationShafqat, N.,Yue, W.W.,Niesen, F.,Oppermann, U.
Crystal Structure of the Human Mgc45594 Gene Product in Complex with Diclofenac
To be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

217705

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