2W98

CRYSTAL STRUCTURE OF HUMAN ZINC-BINDING ALCOHOL DEHYDROGENASE 1 (ZADH1) IN TERNARY COMPLEX WITH NADP AND PHENYLBUTAZONE

Summary for 2W98

• Entry DOI: 10.2210/pdb2w98/pdb
• Related: 2VNA 2W4Q
• Descriptor: PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE, ... (8 entities in total)
• Functional Keywords: 15-oxoprostalglandin, medium-chain dehydrogenase/reductase, oxidoreductase
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm (By similarity): Q8N8N7
• Total number of polymer chains: 2
• Total formula weight: 82976.23

Authors

Shafqat, N.,Yue, W.W.,Muniz, J.,Picaud, S.,Niesen, F.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2009-01-22, release date: 2009-04-07, Last modification date: 2023-12-13)

• Primary citation: Shafqat, N.,Yue, W.W.,Niesen, F.,Oppermann, U.; Crystal Structure of Human Zinc-Binding Alcohol Dehydrogenase 1; To be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)