Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006693 | biological_process | prostaglandin metabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| A | 0047522 | molecular_function | 15-oxoprostaglandin 13-reductase [NAD(P)+] activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006693 | biological_process | prostaglandin metabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| B | 0047522 | molecular_function | 15-oxoprostaglandin 13-reductase [NAD(P)+] activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE NAP A 1350 |
| Chain | Residue |
| A | PRO50 |
| A | ASN231 |
| A | VAL232 |
| A | CYS253 |
| A | GLY254 |
| A | GLN255 |
| A | ILE256 |
| A | SER257 |
| A | TYR259 |
| A | PHE287 |
| A | VAL289 |
| A | THR139 |
| A | MET332 |
| A | MET333 |
| A | GLY335 |
| A | ASN337 |
| A | P1Z1351 |
| A | HOH2218 |
| A | HOH2221 |
| A | HOH2222 |
| A | HOH2223 |
| A | HOH2224 |
| A | GLY165 |
| A | HOH2225 |
| A | HOH2226 |
| A | HOH2227 |
| A | HOH2228 |
| A | HOH2229 |
| A | HOH2231 |
| A | HOH2232 |
| A | ALA166 |
| A | CYS167 |
| A | CYS187 |
| A | GLY188 |
| A | LYS192 |
| A | TYR208 |
| site_id | AC2 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE NAP B 1355 |
| Chain | Residue |
| B | PRO50 |
| B | THR139 |
| B | GLY165 |
| B | ALA166 |
| B | CYS167 |
| B | CYS187 |
| B | GLY188 |
| B | LYS192 |
| B | TYR208 |
| B | ASN231 |
| B | VAL232 |
| B | CYS253 |
| B | GLY254 |
| B | GLN255 |
| B | ILE256 |
| B | SER257 |
| B | TYR259 |
| B | PHE287 |
| B | LEU288 |
| B | VAL289 |
| B | MET332 |
| B | MET333 |
| B | GLY335 |
| B | ASN337 |
| B | P1Z1356 |
| B | HOH2231 |
| B | HOH2233 |
| B | HOH2237 |
| B | HOH2238 |
| B | HOH2239 |
| B | HOH2240 |
| B | HOH2241 |
| B | HOH2242 |
| B | HOH2243 |
| B | HOH2244 |
| B | HOH2245 |
| B | HOH2246 |
| B | HOH2247 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE P1Z B 1356 |
| Chain | Residue |
| B | TYR51 |
| B | ILE65 |
| B | TYR259 |
| B | TYR265 |
| B | LEU288 |
| B | VAL289 |
| B | NAP1355 |
| B | P1Z1358 |
| B | HOH2248 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE P1Z A 1351 |
| Chain | Residue |
| A | TYR51 |
| A | TYR64 |
| A | PHE99 |
| A | CYS253 |
| A | TYR259 |
| A | TYR265 |
| A | LEU288 |
| A | LEU290 |
| A | NAP1350 |
| A | HOH2173 |
| A | HOH2233 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE P1Z A 1352 |
| Chain | Residue |
| A | P1Z1353 |
| A | PO41356 |
| B | TYR64 |
| B | P1Z1357 |
| A | TYR64 |
| A | TYR100 |
| A | LEU290 |
| A | ASN291 |
| A | LYS293 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE P1Z B 1357 |
| Chain | Residue |
| A | LYS293 |
| A | P1Z1352 |
| A | HOH2175 |
| A | HOH2177 |
| B | LEU290 |
| B | ASN291 |
| B | LYS293 |
| B | ASP294 |
| B | P1Z1358 |
| B | HOH2189 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE P1Z B 1358 |
| Chain | Residue |
| A | TYR64 |
| A | HOH2048 |
| B | PHE99 |
| B | TYR100 |
| B | LEU290 |
| B | P1Z1356 |
| B | P1Z1357 |
| B | HOH2249 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE P1Z B 1359 |
| Chain | Residue |
| B | THR97 |
| B | GLU115 |
| B | PHE129 |
| B | LYS293 |
| B | PO41360 |
| B | HOH2072 |
| B | HOH2250 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE P1Z A 1353 |
| Chain | Residue |
| A | THR97 |
| A | GLU115 |
| A | VAL117 |
| A | PHE129 |
| A | PHE296 |
| A | GLU297 |
| A | P1Z1352 |
| A | PO41355 |
| A | HOH2234 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1360 |
| Chain | Residue |
| B | GLY77 |
| B | SER98 |
| B | PHE99 |
| B | MET135 |
| B | P1Z1359 |
| B | HOH2251 |
| B | HOH2252 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1354 |
| Chain | Residue |
| A | PRO102 |
| A | GLN104 |
| A | VAL107 |
| A | ILE108 |
| A | LEU109 |
| A | HOH2235 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1355 |
| Chain | Residue |
| A | GLY78 |
| A | THR97 |
| A | SER98 |
| A | PHE99 |
| A | PHE129 |
| A | LEU130 |
| A | P1Z1353 |
| A | HOH2237 |
| A | HOH2238 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1356 |
| Chain | Residue |
| A | THR66 |
| A | TYR100 |
| A | P1Z1352 |
| A | HOH2239 |
| B | ASP63 |
| B | TYR64 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1361 |
| Chain | Residue |
| B | PRO102 |
| B | GLN104 |
| B | VAL107 |
| B | ILE108 |
| B | LEU109 |
| B | HOH2253 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE LMR B 1362 |
| Chain | Residue |
| A | ILE349 |
| B | PHE95 |
| B | NA1364 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 1363 |
| Chain | Residue |
| B | ASP94 |
| B | PHE95 |
| B | LYS116 |
| B | VAL117 |
| B | HOH2033 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA B 1364 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1guf |
| Chain | Residue | Details |
| A | THR60 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1guf |
| Chain | Residue | Details |
| B | THR60 | |
