3PFW

Crystal structure of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS) complex with NAD, a binary form

Summary for 3PFW

• Entry DOI: 10.2210/pdb3pfw/pdb
• Related: 3H9E
• Descriptor: Glyceraldehyde-3-phosphate dehydrogenase, testis-specific, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (4 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, oxidoreductase, sperm-specific isozyme
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm (By similarity): O14556
• Total number of polymer chains: 2
• Total formula weight: 77475.54

Authors

Chaikuad, A.,Shafqat, N.,Yue, W.W.,Cocking, R.,Bray, J.E.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2010-10-29, release date: 2010-12-15, Last modification date: 2023-09-06)

• Primary citation: Chaikuad, A.,Shafqat, N.,Al-Mokhtar, R.,Cameron, G.,Clarke, A.R.,Brady, R.L.,Oppermann, U.,Frayne, J.,Yue, W.W.; Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS.; Biochem.J., 435:401-409, 2011; PubMed: 21269272; DOI: 10.1042/BJ20101442

Experimental method

X-RAY DIFFRACTION (2.15 Å)