3PFW
Crystal structure of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDS) complex with NAD, a binary form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (O, P) | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | polymer | 346 | 37844.1 | 2 | UniProt (O14556) Pfam (PF00044) Pfam (PF02800) | Homo sapiens (human) | Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2, GAPDH-2, Spermatogenic glyceraldehyde-3-phosphate dehydrogenase |
| 2 | C, G (O, P) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, E, F, H, I (O, P) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 4 | J, K (O, P) | water | water | 18.0 | 303 | Chemie (HOH) |
Sequence modifications
O, P: 69 - 407 (UniProt: O14556)
| PDB | External Database | Details |
|---|---|---|
| Ala 408 | - | expression tag |
| Glu 409 | - | expression tag |
| Asn 410 | - | expression tag |
| Leu 411 | - | expression tag |
| Tyr 412 | - | expression tag |
| Phe 413 | - | expression tag |
| Gln 414 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75688.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1787.3 | |
| All* | Total formula weight | 77475.5 |
