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4UN2
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CRYSTAL STRUCTURE OF THE UBA DOMAIN OF DSK2 IN COMPLEX WITH UBIQUITIN
Descriptor:UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2
Authors:Michielssens, S., Peters, J.H., Ban, D., Pratihar, S., Seeliger, D., Sharma, M., Giller, K., Sabo, T.M., Becker, S., Lee, D., Griesinger, C., de Groot, B.L.
Deposit date:2014-05-23
Release date:2014-08-27
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014
2WFI
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ATOMIC RESOLUTION CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF HUMAN CYCLOPHILIN G
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G, MAGNESIUM ION
Authors:Stegmann, C.M., Sheldrick, G.M., Wahl, M.C.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:The Thermodynamic Influence of Trapped Water Molecules on a Protein-Ligand Interaction
Angew.Chem.Int.Ed.Engl., 48, 2009
2WFJ
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ATOMIC RESOLUTION CRYSTAL STRUCTURE OF THE PPIASE DOMAIN OF HUMAN CYCLOPHILIN G IN COMPLEX WITH CYCLOSPORIN A.
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G, CYCLOSPORIN A, 1,2-ETHANEDIOL, ...
Authors:Stegmann, C.M., Sheldrick, G.M., Wahl, M.C.
Deposit date:2009-04-06
Release date:2009-06-16
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (0.75 Å)
Cite:The Thermodynamic Influence of Trapped Water Molecules on a Protein-Ligand Interaction.
Angew.Chem.Int.Ed.Engl., 48, 2009
4EOW
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CRYSTAL STRUCTURE OF A DISEASE-ASSOCIATED ANTI-HUMAN GM-CSF AUTOANTIBODY MB007
Descriptor:MB007 human IgG1 Fab fragment heavy chain, MB007 IgG1 Fab fragment light chain
Authors:Blech, M.
Deposit date:2012-04-16
Release date:2012-08-22
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications.
Biochem.J., 447, 2012
4YGV
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REVERSAL AGENT FOR DABIGATRAN
Descriptor:aDabi-Fab2a heavy chain, aDabi-Fab2a light chain, GLYCEROL
Authors:Schiele, F., Nar, H.
Deposit date:2015-02-26
Release date:2015-06-17
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
4YHI
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REVERSAL AGENT FOR DABIGATRAN
Descriptor:aDabi-Fab2a heavy chain, aDabi-Fab2a light chain, N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine
Authors:Schiele, F., Nar, H.
Deposit date:2015-02-27
Release date:2016-01-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
4YHK
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REVERSAL AGENT FOR DABIGATRAN
Descriptor:aDabi-Fab2a heavy chain, aDabi-Fab2a light chain, N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine, ...
Authors:Schiele, F., Nar, H.
Deposit date:2015-02-27
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
4YHL
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REVERSAL AGENT FOR DABIGATRAN
Descriptor:aDabi-Fab2b heavy chain, aDabi-Fab2b light chain
Authors:Schiele, F., Nar, H.
Deposit date:2015-02-27
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
4YHM
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REVERSAL AGENT FOR DABIGATRAN
Descriptor:aDabi-Fab2b heavy chain, aDabi-Fab2b light chain, N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine
Authors:Schiele, F., Nar, H.
Deposit date:2015-02-27
Release date:2016-01-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
4YHN
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DABIGATRAN REVERSAL AGENT
Descriptor:aDabi-Fab3 heavy chain, aDabi-Fab3 light chain
Authors:Schiele, F., Nar, H.
Deposit date:2015-02-27
Release date:2016-02-10
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015
4YHO
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REVERSAL AGENT FOR DABIGATRAN
Descriptor:aDabi-Fab3 heavy chain, aDabi-Fab3 light chain, N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-pyridin-2-yl-beta-alanine
Authors:Schiele, F., Nar, H.
Deposit date:2015-02-27
Release date:2016-01-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structure-guided residence time optimization of a dabigatran reversal agent.
Mabs, 7, 2015