Author results

8HVP
  • Download 8hvp
  • View 8hvp
Molmil generated image of 8hvp
STRUCTURE AT 2.5-ANGSTROMS RESOLUTION OF CHEMICALLY SYNTHESIZED HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 PROTEASE COMPLEXED WITH A HYDROXYETHYLENE*-BASED INHIBITOR
Descriptor:HIV-1 PROTEASE, INHIBITOR VAL-SER-GLN-ASN-LEU-PSI(CH(OH)-CH2)-VAL-ILE-VAL (U-85548E)
Authors:Jaskolski, M., Miller, M., Tomasselli, A.G., Sawyer, T.K., Staples, D.G., Heinrikson, R.L., Schneider, J., Kent, S.B.H., Wlodawer, A.
Deposit date:1990-10-26
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure at 2.5-A resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor.
Biochemistry, 30, 1991
7HVP
  • Download 7hvp
  • View 7hvp
Molmil generated image of 7hvp
X-RAY CRYSTALLOGRAPHIC STRUCTURE OF A COMPLEX BETWEEN A SYNTHETIC PROTEASE OF HUMAN IMMUNODEFICIENCY VIRUS 1 AND A SUBSTRATE-BASED HYDROXYETHYLAMINE INHIBITOR
Descriptor:HIV-1 PROTEASE, INHIBITOR ACE-SER-LEU-ASN-PHE-PSI(CH(OH)-CH2N)-PRO-ILE VME (JG-365)
Authors:Swain, A.L., Miller, M.M., Green, J., Rich, D.H., Schneider, J., Kent, S.B.H., Wlodawer, A.
Deposit date:1990-09-13
Release date:1993-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitor.
Proc.Natl.Acad.Sci.USA, 87, 1990
6FTS
  • Download 6fts
  • View 6fts
Molmil generated image of 6fts
TETR(D) N82A MUTANT IN COMPLEX WITH PEG4
Descriptor:Tetracycline repressor protein class D, TETRAETHYLENE GLYCOL, CHLORIDE ION
Authors:Hinrichs, W., Palm, G.J., Berndt, L., Girbardt, B.
Deposit date:2018-02-23
Release date:2019-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Modular organisation of inducer recognition and allostery in the tetracycline repressor.
FEBS J., 283, 2016
6FPM
  • Download 6fpm
  • View 6fpm
Molmil generated image of 6fpm
TETR(D) T103A MUTANT IN COMPLEX WITH TETRACYCLINE AND MAGNESIUM
Descriptor:Tetracycline repressor protein class D, TETRACYCLINE, MAGNESIUM ION, ...
Authors:Hinrichs, W., Palm, G.J., Berndt, L., Girbardt, B.
Deposit date:2018-02-11
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Modular organisation of inducer recognition and allostery in the tetracycline repressor.
FEBS J., 283, 2016
6FPL
  • Download 6fpl
  • View 6fpl
Molmil generated image of 6fpl
TETR(D) E147A MUTANT IN COMPLEX WITH TETRACYCLINE AND MAGNESIUM
Descriptor:Tetracycline repressor protein class D, TETRACYCLINE, MAGNESIUM ION, ...
Authors:Hinrichs, W., Palm, G.J., Berndt, L., Girbardt, B.
Deposit date:2018-02-11
Release date:2019-03-13
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:TETR(D) E147A MUTANT IN COMPLEX WITH TETRACYCLINE AND MAGNESIUM
To be published
6ELU
  • Download 6elu
  • View 6elu
Molmil generated image of 6elu
STRUCTURE OF SERUM RESISTANCE ASSOCIATED PROTEIN FROM T. B. RHODESIENSE
Descriptor:Serum resistance associated; VSG protein, G10_3 heavy chain, G10_3 Light chain
Authors:Zoll, S., Higgins, M.K.
Deposit date:2017-09-29
Release date:2018-01-24
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structure of serum resistance-associated protein and its implications for human African trypanosomiasis.
Nat Microbiol, 3, 2018
5MRU
  • Download 5mru
  • View 5mru
Molmil generated image of 5mru
TETR(CLASS A) IN COMPLEX WITH 5A,6-ANHYDROTETRACYCLINE AND MAGNESIUM
Descriptor:Tetracycline Repressor, class A, 5A,6-ANHYDROTETRACYCLINE, ...
Authors:Hinrichs, W., Palm, G.J.
Deposit date:2016-12-26
Release date:2018-01-17
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:TetR(class A) in complex with 5a,6-anhydrotetracycline and magnesium
To Be Published
5FKO
  • Download 5fko
  • View 5fko
Molmil generated image of 5fko
TETR(D) E147A MUTANT IN COMPLEX WITH ANHYDROTETRACYCLINE AND MAGNESIUM
Descriptor:TETRACYCLINE REPRESSOR, CLASS D, E147A MUTANT, ...
Authors:Werten, S., Schneider, J., Palm, G.J., Hinrichs, W.
Deposit date:2015-10-17
Release date:2016-04-06
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor
FEBS J., 283, 2016
5FKN
  • Download 5fkn
  • View 5fkn
Molmil generated image of 5fkn
TETR(D) T103A MUTANT IN COMPLEX WITH ANHYDROTETRACYCLINE AND MAGNESIUM, P4(3)2(1)2
Descriptor:TETRACYCLINE REPRESSOR, CLASS D, T103A MUTANT, ...
Authors:Werten, S., Schneider, J., Palm, G.J., Hinrichs, W.
Deposit date:2015-10-17
Release date:2016-04-06
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor
FEBS J., 283, 2016
5FKM
  • Download 5fkm
  • View 5fkm
Molmil generated image of 5fkm
TETR(D) T103A MUTANT IN COMPLEX WITH ANHYDROTETRACYCLINE AND MAGNESIUM, I4(1)22
Descriptor:TETRACYCLINE REPRESSOR, CLASS D, 5A,6-ANHYDROTETRACYCLINE, ...
Authors:Werten, S., Schneider, J., Palm, G.J., Hinrichs, W.
Deposit date:2015-10-17
Release date:2016-04-06
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor
FEBS J., 283, 2016
5FKL
  • Download 5fkl
  • View 5fkl
Molmil generated image of 5fkl
TETR(D) H100A MUTANT IN COMPLEX WITH ANHYDROTETRACYCLINE AND MAGNESIUM
Descriptor:TETRACYCLINE REPRESSOR, CLASS D, 5A,6-ANHYDROTETRACYCLINE, ...
Authors:Werten, S., Schneider, J., Palm, G.J., Hinrichs, W.
Deposit date:2015-10-17
Release date:2016-04-06
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor
FEBS J., 283, 2016
5FKK
  • Download 5fkk
  • View 5fkk
Molmil generated image of 5fkk
TETR(D) N82A MUTANT IN COMPLEX WITH ANHYDROTETRACYCLINE AND MAGNESIUM
Descriptor:TETRACYCLINE REPRESSOR, CLASS D, TETRAETHYLENE GLYCOL, ...
Authors:Werten, S., Schneider, J., Palm, G.J., Hinrichs, W.
Deposit date:2015-10-17
Release date:2016-04-06
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Modular Organisation of Inducer Recognition and Allostery in the Tetracycline Repressor
FEBS J., 283, 2016
4V36
  • Download 4v36
  • View 4v36
Molmil generated image of 4v36
THE STRUCTURE OF L-PGS FROM BACILLUS LICHENIFORMIS
Descriptor:LYSYL-TRNA-DEPENDENT L-YSYL-PHOSPHATIDYLGYCEROL SYNTHASE, 2,6-DIAMINO-HEXANOIC ACID AMIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Krausze, J., Hebecker, S., Heinz, D.W., Moser, J.
Deposit date:2014-10-16
Release date:2015-08-19
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Two Bacterial Resistance Factors Mediating tRNA-Dependent Aminoacylation of Phosphatidylglycerol with Lysine or Alanine.
Proc.Natl.Acad.Sci.USA, 112, 2015
4V35
  • Download 4v35
  • View 4v35
Molmil generated image of 4v35
THE STRUCTURE OF A-PGS FROM PSEUDOMONAS AERUGINOSA
Descriptor:ALANYL-TRNA-DEPENDENT L-ALANYL- PHOPHATIDYLGLYCEROL SYNTHASE, SULFATE ION, GLYCEROL, ...
Authors:Krausze, J., Hebecker, S., Hasenkampf, T., Heinz, D.W., Moser, J.
Deposit date:2014-10-16
Release date:2015-08-19
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of Two Bacterial Resistance Factors Mediating tRNA-Dependent Aminoacylation of Phosphatidylglycerol with Lysine or Alanine.
Proc.Natl.Acad.Sci.USA, 112, 2015
4V34
  • Download 4v34
  • View 4v34
Molmil generated image of 4v34
THE STRUCTURE OF A-PGS FROM PSEUDOMONAS AERUGINOSA (SEMET DERIVATIVE)
Descriptor:ALANYL-TRNA-DEPENDENT L-ALANYL- PHOPHATIDYLGLYCEROL SYNTHASE, CHLORIDE ION, SULFATE ION
Authors:Krausze, J., Hebecker, S., Hasenkampf, T., Heinz, D.W., Moser, J.
Deposit date:2014-10-16
Release date:2015-08-19
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of Two Bacterial Resistance Factors Mediating tRNA-Dependent Aminoacylation of Phosphatidylglycerol with Lysine or Alanine.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R7P
  • Download 4r7p
  • View 4r7p
Molmil generated image of 4r7p
HUMAN UDP-GLUCOSE PYROPHOSPHORYLASE ISOFORM 1 IN COMPLEX WITH UDP-GLUCOSE
Descriptor:UTP--glucose-1-phosphate uridylyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE, SULFATE ION, ...
Authors:Fuehring, J., Cramer, J.T., Schneider, J., Baruch, P., Gerardy-Schahn, R., Fedorov, R.
Deposit date:2014-08-28
Release date:2015-04-22
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:A Quaternary Mechanism Enables the Complex Biological Functions of Octameric Human UDP-glucose Pyrophosphorylase, a Key Enzyme in Cell Metabolism.
Sci Rep, 5
4PHV
  • Download 4phv
  • View 4phv
Molmil generated image of 4phv
X-RAY CRYSTAL STRUCTURE OF THE HIV PROTEASE COMPLEX WITH L-700,417, AN INHIBITOR WITH PSEUDO C2 SYMMETRY
Descriptor:HIV-1 PROTEASE, N,N-BIS(2-HYDROXY-1-INDANYL)-2,6- DIPHENYLMETHYL-4-HYDROXY-1,7-HEPTANDIAMIDE
Authors:Bone, R.
Deposit date:1991-10-04
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-Ray Crystal Structure of the HIV Protease Complex with L-700,417, an Inhibitor with Pseudo C2 Symmetry
J.Am.Chem.Soc., 113, 1991
4HVP
  • Download 4hvp
  • View 4hvp
Molmil generated image of 4hvp
STRUCTURE OF COMPLEX OF SYNTHETIC HIV-1 PROTEASE WITH A SUBSTRATE-BASED INHIBITOR AT 2.3 ANGSTROMS RESOLUTION
Descriptor:HIV-1 PROTEASE, N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide
Authors:Miller, M., Schneider, J., Sathyanarayana, B.K., Toth, M.V., Marshall, G.R., Clawson, L., Selk, L., Kent, S.B.H., Wlodawer, A.
Deposit date:1989-08-08
Release date:1990-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 A resolution.
Science, 246, 1989
4B3A
  • Download 4b3a
  • View 4b3a
Molmil generated image of 4b3a
TETRACYCLINE REPRESSOR CLASS D MUTANT H100A IN COMPLEX WITH TETRACYCLINE
Descriptor:TETRACYCLINE REPRESSOR PROTEIN CLASS D, TETRACYCLINE, CHLORIDE ION, ...
Authors:Eltschkner, S., Schindler, S., Palm, G.J., Schneider, J., Hinrichs, W.
Deposit date:2012-07-23
Release date:2013-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Tetracycline Repressor Class D Mutant H100A in Complex with Tetracycline
To be Published
4B1R
  • Download 4b1r
  • View 4b1r
Molmil generated image of 4b1r
TETRACYCLINE REPRESSOR CLASS D MUTANT H100A IN COMPLEX WITH ISO-7- CHLORTETRACYCLINE
Descriptor:TETRACYCLINE REPRESSOR PROTEIN CLASS D, ISO-7-CHLORTETRACYCLINE, CHLORIDE ION
Authors:Eltschkner, S., Palm, G.J., Schneider, J., Hinrichs, W.
Deposit date:2012-07-12
Release date:2013-07-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Tetracycline Repressor Class D Mutant H100A in Complex with Iso-7-Chlortetracycline
To be Published
3SQF
  • Download 3sqf
  • View 3sqf
Molmil generated image of 3sqf
CRYSTAL STRUCTURE OF MONOMERIC M-PMV RETROVIRAL PROTEASE
Descriptor:Protease
Authors:Jaskolski, M., Kazmierczyk, M., Gilski, M., Krzywda, S., Pichova, I., Zabranska, H., Khatib, F., DiMaio, F., Cooper, S., Thompson, J., Popovic, Z., Baker, D., Group, Foldit Contenders
Deposit date:2011-07-05
Release date:2011-09-21
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (1.6324 Å)
Cite:Crystal structure of a monomeric retroviral protease solved by protein folding game players.
Nat.Struct.Mol.Biol., 18, 2011
3MNQ
  • Download 3mnq
  • View 3mnq
Molmil generated image of 3mnq
CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP-METAVANADATE AND RESVERATROL
Descriptor:Myosin-2 heavy chain, ADP METAVANADATE, MAGNESIUM ION, ...
Authors:Schneider, J., Taft, M., Backhaus, A., Baruch, P., Fedorov, R., Manstein, D.J.
Deposit date:2010-04-22
Release date:2011-04-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of resveratrol regulation of myosin activity.
To be Published
3HVP
  • Download 3hvp
  • View 3hvp
Molmil generated image of 3hvp
CONSERVED FOLDING IN RETROVIRAL PROTEASES. CRYSTAL STRUCTURE OF A SYNTHETIC HIV-1 PROTEASE
Descriptor:UNLIGANDED HIV-1 PROTEASE
Authors:Wlodawer, A., Jaskolski, M., Miller, M.
Deposit date:1989-08-08
Release date:1989-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conserved folding in retroviral proteases: crystal structure of a synthetic HIV-1 protease.
Science, 245, 1989
3HFA
  • Download 3hfa
  • View 3hfa
Molmil generated image of 3hfa
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PROTEASOME OPEN-GATE MUTANT
Descriptor:Proteasome (Beta subunit) PrcB, Proteasome (Alpha subunit) PrcA, DIMETHYLFORMAMIDE
Authors:Li, D., Li, H.
Deposit date:2009-05-11
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.504 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
3HF9
  • Download 3hf9
  • View 3hf9
Molmil generated image of 3hf9
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS PROTEASOME OPEN-GATE MUTANT MODIFIED BY INHIBITOR GL1
Descriptor:Proteasome (Alpha subunit) PrcA, Proteasome (Beta subunit) PrcB
Authors:Li, D., Li, H.
Deposit date:2009-05-11
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.878 Å)
Cite:Inhibitors selective for mycobacterial versus human proteasomes.
Nature, 461, 2009
<12>