1NIG
| |
1M3S
| Crystal structure of YckF from Bacillus subtilis | Descriptor: | Hypothetical protein yckf | Authors: | Sanishvili, R, Wu, R, Kim, D.E, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-06-28 | Release date: | 2003-01-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of Bacillus subtilis YckF: structural and functional evolution. J.Struct.Biol., 148, 2004
|
|
1CRC
| CYTOCHROME C AT LOW IONIC STRENGTH | Descriptor: | CYTOCHROME C, HEME C | Authors: | Sanishvili, R, Volz, K.W, Westbrook, E.M, Margoliash, E. | Deposit date: | 1995-03-22 | Release date: | 1996-03-08 | Last modified: | 2021-03-10 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | The low ionic strength crystal structure of horse cytochrome c at 2.1 A resolution and comparison with its high ionic strength counterpart. Structure, 3, 1995
|
|
1MKZ
| Crystal structure of MoaB protein at 1.6 A resolution. | Descriptor: | ACETIC ACID, Molybdenum cofactor biosynthesis protein B, SULFATE ION | Authors: | Sanishvili, R, Skarina, T, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-08-29 | Release date: | 2003-04-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of Escherichia coli MoaB suggests a probable role in molybdenum cofactor synthesis. J.Biol.Chem., 279, 2004
|
|
1M33
| Crystal Structure of BioH at 1.7 A | Descriptor: | 1,2-ETHANEDIOL, 3-HYDROXY-PROPANOIC ACID, BioH protein | Authors: | Sanishvili, R, Savchenko, A, Skarina, T, Edwards, A, Joachimiak, A, Yakunin, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-06-26 | Release date: | 2003-01-21 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J.Biol.Chem., 278, 2003
|
|
1NI9
| 2.0 A structure of glycerol metabolism protein from E. coli | Descriptor: | Protein glpX, SULFATE ION | Authors: | Sanishvili, R, Brunzelle, J, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-12-23 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli. J.Biol.Chem., 284, 2009
|
|
1K7K
| crystal structure of RdgB- inosine triphosphate pyrophosphatase from E. coli | Descriptor: | Hypothetical protein yggV | Authors: | Sanishvili, R, Joachimiak, A, Edwards, A, Savchenko, A, Skarina, T, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-10-19 | Release date: | 2002-08-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli. J.Mol.Biol., 374, 2007
|
|
2OBZ
| |
4ZSY
| Pig Brain GABA-AT inactivated by (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid. | Descriptor: | (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... | Authors: | Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D. | Deposit date: | 2015-05-14 | Release date: | 2015-07-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid. Acs Chem.Biol., 10, 2015
|
|
1NOG
| Crystal Structure of Conserved Protein 0546 from Thermoplasma Acidophilum | Descriptor: | conserved hypothetical protein TA0546 | Authors: | Saridakis, V, Sanishvili, R, Iakounine, A, Xu, X, Pennycooke, M, Gu, J, Joachimiak, A, Arrowsmith, C.H, Edwards, A.M, Christendat, D, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2003-01-16 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase. J.Biol.Chem., 279, 2004
|
|
4Y0I
| GABA-aminotransferase inactivated by conformationally-restricted inactivator | Descriptor: | 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, 4-aminobutyrate aminotransferase, mitochondrial, ... | Authors: | Wu, R, Sanishvili, R, Lee, H.V, Dustin, D.H, Emma, D, Neil, K, Silverman, R.B, Liu, D. | Deposit date: | 2015-02-06 | Release date: | 2016-02-17 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.662 Å) | Cite: | GABA-aminotransferase inactivated by conformationally-restricted inactivator To Be Published
|
|
4ZSW
| Pig Brain GABA-AT inactivated by (E)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic acid | Descriptor: | (1S)-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]cyclopent-3-ene-1,3-dicarboxylic acid, 4-aminobutyrate aminotransferase, mitochondrial, ... | Authors: | Wu, R, Lee, H, Le, H.V, Doud, E, Sanishvili, R, Compton, P, Kelleher, N.L, Silverman, R.B, Liu, D. | Deposit date: | 2015-05-14 | Release date: | 2015-07-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid. Acs Chem.Biol., 10, 2015
|
|
1YB2
| Structure of a putative methyltransferase from Thermoplasma acidophilum. | Descriptor: | hypothetical protein Ta0852 | Authors: | Cuff, M.E, Xu, X, Edwards, A, Savchenko, A, Sanishvili, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-12-18 | Release date: | 2005-02-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structure of a putative methyltransferase from Thermoplasma acidophilum. To be Published
|
|
1SRV
| THERMUS THERMOPHILUS GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 192-336 | Descriptor: | PROTEIN (GROEL (HSP60 CLASS)) | Authors: | Walsh, M.A, Dementieva, I, Evans, G, Sanishvili, R, Joachimiak, A. | Deposit date: | 1999-03-02 | Release date: | 1999-03-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Taking MAD to the extreme: ultrafast protein structure determination. Acta Crystallogr.,Sect.D, 55, 1999
|
|
5EDV
| Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex | Descriptor: | E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J. | Deposit date: | 2015-10-22 | Release date: | 2016-01-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.48 Å) | Cite: | Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation. Nature, 529, 2016
|
|
1US0
| Human Aldose Reductase in complex with NADP+ and the inhibitor IDD594 at 0.66 Angstrom | Descriptor: | ALDOSE REDUCTASE, CITRIC ACID, IDD594, ... | Authors: | Howard, E.I, Sanishvili, R, Cachau, R.E, Mitschler, A, Chevrier, B, Barth, P, Lamour, V, Van Zandt, M, Sibley, E, Bon, C, Moras, D, Schneider, T.R, Joachimiak, A, Podjarny, A. | Deposit date: | 2003-11-16 | Release date: | 2004-05-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (0.66 Å) | Cite: | Ultrahigh Resolution Drug Design I: Details of Interactions in Human Aldose Reductase-Inhibitor Complex at 0.66 A. Proteins, 55, 2004
|
|
6AUN
| calcium-independent phospholipase A2 beta | Descriptor: | PLA2G6, iPLA2beta | Authors: | Malley, K, Koroleva, O, Miller, I, Sanishvili, R, Jenkins, C.M, Gross, R.W, Korolev, S. | Deposit date: | 2017-09-01 | Release date: | 2018-03-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3.951 Å) | Cite: | The structure of iPLA2beta reveals dimeric active sites and suggests mechanisms of regulation and localization. Nat Commun, 9, 2018
|
|
5T4L
| PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | Descriptor: | (4R)-4-amino-6-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}hexanoic acid, Aspartate aminotransferase | Authors: | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | Deposit date: | 2016-08-29 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5T4K
| PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | Descriptor: | (4S)-5-fluoro-4-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]pentanoic acid, HTH-type transcriptional regulatory protein GabR | Authors: | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | Deposit date: | 2016-08-29 | Release date: | 2017-03-29 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.245 Å) | Cite: | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5T4J
| PLP and GABA Trigger GabR-Mediated Transcription Regulation in Bacillus subsidies via External Aldimine Formation | Descriptor: | GAMMA-AMINO-BUTANOIC ACID, HTH-type transcriptional regulatory protein GabR, PYRIDOXAL-5'-PHOSPHATE | Authors: | Wu, R, Sanishvili, R, Belitsky, B.R, Juncosa, J.I, Le, H.V, Lehrer, H.J.S, Farley, M, Silverman, R.B, Petsko, G.A, Ringe, D, Liu, D. | Deposit date: | 2016-08-29 | Release date: | 2017-03-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.231 Å) | Cite: | PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
2O53
| Crystal structure of apo-Aspartoacylase from human brain | Descriptor: | Aspartoacylase, PHOSPHATE ION, ZINC ION | Authors: | Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E. | Deposit date: | 2006-12-05 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue. Biochemistry, 47, 2008
|
|
1PUY
| 1.5 A resolution structure of a synthetic DNA hairpin with a stilbenediether linker | Descriptor: | 5'-D(*GP*TP*TP*TP*TP*GP*(S02)P*CP*AP*AP*AP*AP*C)-3', MAGNESIUM ION | Authors: | Egli, M, Tereshko, V, Murshudov, G, Sanishvili, R, Liu, X, Lewis, F.D. | Deposit date: | 2003-06-25 | Release date: | 2003-10-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker J.Am.Chem.Soc., 125, 2003
|
|
2O4H
| Human brain aspartoacylase complex with intermediate analog (N-phosphonomethyl-L-aspartate) | Descriptor: | Aspartoacylase, N-[HYDROXY(METHYL)PHOSPHORYL]-L-ASPARTIC ACID, ZINC ION | Authors: | Le Coq, J, Pavlovsky, A, Sanishvili, R, Viola, R.E. | Deposit date: | 2006-12-04 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Examination of the Mechanism of Human Brain Aspartoacylase through the Binding of an Intermediate Analogue. Biochemistry, 47, 2008
|
|
4LMG
| Crystal structure of AFT2 in complex with DNA | Descriptor: | 5'-D(*AP*AP*GP*TP*GP*CP*AP*CP*CP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*TP*GP*GP*GP*TP*GP*CP*AP*CP*T)-3', Iron-regulated transcriptional activator AFT2, ... | Authors: | Poor, C.B, Sanishvili, R, Schuermann, J.P, He, C. | Deposit date: | 2013-07-10 | Release date: | 2014-03-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular mechanism and structure of the Saccharomyces cerevisiae iron regulator Aft2. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
1I3W
| ACTINOMYCIN D BINDING TO CGATCGATCG | Descriptor: | 5'-D(*C*GP*AP*TP*CP*GP*AP*(BRU)P*CP*GP)-3', ACTINOMYCIN D | Authors: | Robinson, H, Gao, Y.-G, Yang, X.-L, Sanishvili, R, Joachimiak, A, Wang, A.H.-J. | Deposit date: | 2001-02-17 | Release date: | 2001-05-21 | Last modified: | 2024-07-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystallographic Analysis of a Novel Complex of Actinomycin D Bound to the DNA Decamer Cgatcgatcg. Biochemistry, 40, 2001
|
|