Author results

5DLI
  • Download 5dli
  • View 5dli
Molmil generated image of 5dli
CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38
Descriptor:Superoxide dismutase [Cu-Zn], GLYCEROL, IODIDE ION
Authors:Sangwan, S., Zhao, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2015-09-05
Release date:2016-09-14
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5IIW
  • Download 5iiw
  • View 5iiw
Molmil generated image of 5iiw
CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38 WITHOUT POTASSIUM IODIDE
Descriptor:Superoxide dismutase [Cu-Zn]
Authors:Sangwan, S., Zhao, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-03-01
Release date:2017-06-28
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WMJ
  • Download 5wmj
  • View 5wmj
Molmil generated image of 5wmj
KVWGSI SEGMENT FROM SUPEROXIDE DISMUTASE 1,RESIDUES 30-35
Descriptor:Superoxide dismutase [Cu-Zn], trifluoroacetic acid
Authors:Sangwan, S., Sawaya, M., Eisenberg, D.
Deposit date:2017-07-28
Release date:2018-03-28
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
5WOR
  • Download 5wor
  • View 5wor
Molmil generated image of 5wor
CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38 WITH FAMILIAL MUTATION G37R
Descriptor:Superoxide dismutase [Cu-Zn], MALONATE ION, GLYCEROL
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2017-08-02
Release date:2018-05-30
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
6B79
  • Download 6b79
  • View 6b79
Molmil generated image of 6b79
CURVED PAIR OF SHEETS FORMED FROM SOD1 RESIDUES 28-38 WITH FAMILIAL MUTATION G37R.
Descriptor:Superoxide dismutase [Cu-Zn], 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2017-10-03
Release date:2018-05-30
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
4OLR
  • Download 4olr
  • View 4olr
Molmil generated image of 4olr
[LEU-5]-ENKEPHALIN MUTANT - YVVFV
Descriptor:[Leu-5]-Enkephalin mutant - YVVFV, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Sangwan, S., Eisenberg, D., Sawaya, M.R., Do, T.D., Bowers, M.T., Lapointe, N.E., Teplow, D.B., Feinstein, S.C.
Deposit date:2014-01-24
Release date:2014-07-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
4ONK
  • Download 4onk
  • View 4onk
Molmil generated image of 4onk
[LEU-5]-ENKEPHALIN MUTANT - YVVFL
Descriptor:[Leu-5]-Enkephalin mutant - YVVFL
Authors:Sangwan, S., Eisenberg, D., Sawaya, M.R., Do, T.D., Bowers, M.T., Lapointe, N.E., Teplow, D.B., Feinstein, S.C.
Deposit date:2014-01-28
Release date:2014-07-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
5TXD
  • Download 5txd
  • View 5txd
Molmil generated image of 5txd
STRUCTURE OF AMYLOID-BETA DERIVED PEPTIDE - NKGAIF
Descriptor:Amyloid beta A4 protein, PHOSPHATE ION
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXH
  • Download 5txh
  • View 5txh
Molmil generated image of 5txh
POLYMORPHIC FORM 2 OF AMYLOID-BETA DERIVED PEPTIDE - IFAEDV
Descriptor:IFAEDV, ISOPROPYL ALCOHOL
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXJ
  • Download 5txj
  • View 5txj
Molmil generated image of 5txj
POLYMORPHIC FORM 1 OF AMYLOID-BETA DERIVED PEPTIDE - IFAEDV
Descriptor:amyloid-beta derived peptide
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
4RIL
  • Download 4ril
  • View 4ril
Molmil generated image of 4ril
STRUCTURE OF THE AMYLOID FORMING SEGMENT, GAVVTGVTAVA, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 68-78, DETERMINED BY ELECTRON DIFFRACTION
Descriptor:Alpha-synuclein
Authors:Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2018-04-25
Method:ELECTRON CRYSTALLOGRAPHY (1.43 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4ZNN
  • Download 4znn
  • View 4znn
Molmil generated image of 4znn
MICROED STRUCTURE OF THE SEGMENT, GVVHGVTTVA, FROM THE A53T FAMILIAL MUTANT OF PARKINSON'S DISEASE PROTEIN, ALPHA-SYNUCLEIN RESIDUES 47-56
Descriptor:Alpha-synuclein
Authors:Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S.
Deposit date:2015-05-05
Release date:2015-09-09
Last modified:2017-09-06
Method:ELECTRON CRYSTALLOGRAPHY (1.41 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
5E5V
  • Download 5e5v
  • View 5e5v
Molmil generated image of 5e5v
STRUCTURE OF AMYLOID FORMING PEPTIDE NFGAILS (RESIDUES 22-28) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:NFGAILS (22-28) from islet amyloid polypeptide, synthesized
Authors:Soriaga, A.B., Macdonald, R., Sawaya, M.R., Sangwan, S., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
4RIK
  • Download 4rik
  • View 4rik
Molmil generated image of 4rik
AMYLOID FORMING SEGMENT, AVVTGVTAV, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 69-77
Descriptor:Alpha-synuclein
Authors:Guenther, E.L., Sawaya, M.R., Ivanova, M., Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
5E5X
  • Download 5e5x
  • View 5e5x
Molmil generated image of 5e5x
STRUCTURE OF THE AMYLOID FORMING PEPTIDE ANFLVH (RESIDUES 13-18) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:ANFLVH (residues 13-18) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E5Z
  • Download 5e5z
  • View 5e5z
Molmil generated image of 5e5z
STRUCTURE OF THE AMYLOID FORMING PEPTIDE LVHSSN (RESIDUES
Descriptor:LVHSSN (residues 16-21) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.664 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E61
  • Download 5e61
  • View 5e61
Molmil generated image of 5e61
STRUCTURE OF AMYLOID-FORMING PEPTIDE FGAILSS (RESIDUES 23-29) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:FGAILSS (residues 23-29) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016