Author results

5DLI
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CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38
Descriptor:Superoxide dismutase [Cu-Zn], GLYCEROL, IODIDE ION
Authors:Sangwan, S., Zhao, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2015-09-05
Release date:2016-09-14
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5IIW
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CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38 WITHOUT POTASSIUM IODIDE
Descriptor:Superoxide dismutase [Cu-Zn]
Authors:Sangwan, S., Zhao, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-03-01
Release date:2017-06-28
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5WMJ
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KVWGSI SEGMENT FROM SUPEROXIDE DISMUTASE 1,RESIDUES 30-35
Descriptor:Superoxide dismutase [Cu-Zn], trifluoroacetic acid
Authors:Sangwan, S., Sawaya, M., Eisenberg, D.
Deposit date:2017-07-28
Release date:2018-03-28
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
5WOR
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CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38 WITH FAMILIAL MUTATION G37R
Descriptor:Superoxide dismutase [Cu-Zn], MALONATE ION, GLYCEROL
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2017-08-02
Release date:2018-05-30
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
6B79
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CURVED PAIR OF SHEETS FORMED FROM SOD1 RESIDUES 28-38 WITH FAMILIAL MUTATION G37R.
Descriptor:Superoxide dismutase [Cu-Zn], 7-hydroxy-8-[(E)-phenyldiazenyl]naphthalene-1,3-disulfonic acid
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.S.
Deposit date:2017-10-03
Release date:2018-05-30
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structures of corkscrew-forming segments of SOD1 reveal varied oligomer conformations.
Protein Sci., 27, 2018
4OLR
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[LEU-5]-ENKEPHALIN MUTANT - YVVFV
Descriptor:[Leu-5]-Enkephalin mutant - YVVFV, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Sangwan, S., Eisenberg, D., Sawaya, M.R., Do, T.D., Bowers, M.T., Lapointe, N.E., Teplow, D.B., Feinstein, S.C.
Deposit date:2014-01-24
Release date:2014-07-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
4ONK
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[LEU-5]-ENKEPHALIN MUTANT - YVVFL
Descriptor:[Leu-5]-Enkephalin mutant - YVVFL
Authors:Sangwan, S., Eisenberg, D., Sawaya, M.R., Do, T.D., Bowers, M.T., Lapointe, N.E., Teplow, D.B., Feinstein, S.C.
Deposit date:2014-01-28
Release date:2014-07-02
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants.
J.Phys.Chem.B, 118, 2014
5TXD
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STRUCTURE OF AMYLOID-BETA DERIVED PEPTIDE - NKGAIF
Descriptor:Amyloid beta A4 protein, PHOSPHATE ION
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.452 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXH
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POLYMORPHIC FORM 2 OF AMYLOID-BETA DERIVED PEPTIDE - IFAEDV
Descriptor:IFAEDV, ISOPROPYL ALCOHOL
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
5TXJ
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POLYMORPHIC FORM 1 OF AMYLOID-BETA DERIVED PEPTIDE - IFAEDV
Descriptor:amyloid-beta derived peptide
Authors:Sangwan, S., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-11-16
Release date:2017-11-15
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Distal amyloid beta-protein fragments template amyloid assembly.
Protein Sci., 27, 2018
7KKJ
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STRUCTURE OF ANTI-SARS-COV-2 SPIKE NANOBODY MNB6
Descriptor:Synthetic nanobody mNb6, SULFATE ION, CHLORIDE ION
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKK
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY NB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody Nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKL
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY MNB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody mNb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
4RIL
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STRUCTURE OF THE AMYLOID FORMING SEGMENT, GAVVTGVTAVA, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 68-78, DETERMINED BY ELECTRON DIFFRACTION
Descriptor:Alpha-synuclein
Authors:Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2018-04-25
Method:ELECTRON CRYSTALLOGRAPHY (1.43 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4ZNN
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MICROED STRUCTURE OF THE SEGMENT, GVVHGVTTVA, FROM THE A53T FAMILIAL MUTANT OF PARKINSON'S DISEASE PROTEIN, ALPHA-SYNUCLEIN RESIDUES 47-56
Descriptor:Alpha-synuclein
Authors:Rodriguez, J.A., Ivanova, M., Sawaya, M.R., Cascio, D., Reyes, F., Shi, D., Johnson, L., Guenther, E., Sangwan, S., Hattne, J., Nannenga, B., Brewster, A.S., Messerschmidt, M., Boutet, S., Sauter, N.K., Gonen, T., Eisenberg, D.S.
Deposit date:2015-05-05
Release date:2015-09-09
Last modified:2019-12-18
Method:ELECTRON CRYSTALLOGRAPHY (1.41 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
5E5V
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STRUCTURE OF AMYLOID FORMING PEPTIDE NFGAILS (RESIDUES 22-28) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:NFGAILS (22-28) from islet amyloid polypeptide, synthesized
Authors:Soriaga, A.B., Macdonald, R., Sawaya, M.R., Sangwan, S., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
7KDT
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HUMAN TOM70 IN COMPLEX WITH SARS COV2 ORF9B
Descriptor:Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 2020
4RIK
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AMYLOID FORMING SEGMENT, AVVTGVTAV, FROM THE NAC DOMAIN OF PARKINSON'S DISEASE PROTEIN ALPHA-SYNUCLEIN, RESIDUES 69-77
Descriptor:Alpha-synuclein
Authors:Guenther, E.L., Sawaya, M.R., Ivanova, M., Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2015-10-07
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
5E5X
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE ANFLVH (RESIDUES 13-18) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:ANFLVH (residues 13-18) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E5Z
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE LVHSSN (RESIDUES
Descriptor:LVHSSN (residues 16-21) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.664 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E61
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STRUCTURE OF AMYLOID-FORMING PEPTIDE FGAILSS (RESIDUES 23-29) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:FGAILSS (residues 23-29) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
171588
PDB entries from 2020-11-25