Author results

4DQN
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CRYSTAL STRUCTURE OF THE BRANCHED-CHAIN AMINOTRANSFERASE FROM STREPTOCOCCUS MUTANS
Descriptor:Putative branched-chain amino acid aminotransferase IlvE
Authors:Ruan, J., Li, S.T.
Deposit date:2012-02-16
Release date:2013-01-02
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure of the branched-chain aminotransferase from Streptococcus mutans
Acta Crystallogr.,Sect.D, 68, 2012
6CB8
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CRYO-EM STRUCTURE OF THE GASDERMIN A3 MEMBRANE PORE
Descriptor:Gasdermin-A3, CARDIOLIPIN
Authors:Ruan, J., Wu, H.
Deposit date:2018-02-02
Release date:2018-04-25
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the gasdermin A3 membrane pore.
Nature, 557, 2018
3OTR
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2.75 ANGSTROM CRYSTAL STRUCTURE OF ENOLASE 1 FROM TOXOPLASMA GONDII
Descriptor:Enolase, CHLORIDE ION, SULFATE ION
Authors:Minasov, G., Ruan, J., Shuvalova, L., Halavaty, A., Ngo, H., Tomavo, S., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-09-13
Release date:2010-09-22
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions.
Acta Crystallogr.,Sect.D, 71, 2015
3JBL
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CRYO-EM STRUCTURE OF THE ACTIVATED NAIP2/NLRC4 INFLAMMASOME REVEALS NUCLEATED POLYMERIZATION
Descriptor:NLR family CARD domain-containing protein 4
Authors:Zhang, L., Chen, S., Ruan, J., Wu, J., Tong, A.B., Yin, Q., Li, Y., David, L., Lu, A., Wang, W.L., Marks, C., Ouyang, Q., Zhang, X., Mao, Y., Wu, H.
Deposit date:2015-09-05
Release date:2015-10-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Science, 350, 2015
3LWE
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THE CRYSTAL STRUCTURE OF MPP8
Descriptor:M-phase phosphoprotein 8
Authors:Li, Z., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)
Deposit date:2010-02-23
Release date:2010-03-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3MP1
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COMPLEX STRUCTURE OF SGF29 AND TRIMETHYLATED H3K4
Descriptor:Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, H3K4me3 peptide, MALTOSE, ...
Authors:Li, J., Ruan, J., Wu, M., Xue, X., Zang, J.
Deposit date:2010-04-24
Release date:2011-05-04
Last modified:2017-06-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3MP6
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COMPLEX STRUCTURE OF SGF29 AND DIMETHYLATED H3K4
Descriptor:Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, H3K4me2 peptide, MALTOSE
Authors:Li, J., Wu, M., Ruan, J., Zang, J.
Deposit date:2010-04-25
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3MP8
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CRYSTAL STRUCTURE OF SGF29 TUDOR DOMAIN
Descriptor:Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, MALTOSE, GLYCEROL, ...
Authors:Li, J., Wu, M., Ruan, J., Zang, J.
Deposit date:2010-04-26
Release date:2011-05-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation
Embo J., 30, 2011
3R93
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CRYSTAL STRUCTURE OF THE CHROMO DOMAIN OF M-PHASE PHOSPHOPROTEIN 8 BOUND TO H3K9ME3 PEPTIDE
Descriptor:M-phase phosphoprotein 8, H3K9Me3 peptide, UNKNOWN ATOM OR ION
Authors:Li, J., Li, Z., Ruan, J., Xu, C., Tong, Y., Pan, P.W., Tempel, W., Crombet, L., Min, J., Zang, J., Structural Genomics Consortium (SGC)
Deposit date:2011-03-24
Release date:2011-04-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.057 Å)
Cite:Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3T41
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1.95 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF EPIDERMIN LEADER PEPTIDE PROCESSING SERINE PROTEASE (EPIP) S393A MUTANT FROM STAPHYLOCOCCUS AUREUS
Descriptor:Epidermin leader peptide processing serine protease EpiP, CALCIUM ION, CHLORIDE ION
Authors:Minasov, G., Kuhn, M., Ruan, J., Halavaty, A., Shuvalova, L., Dubrovska, I., Winsor, J., Bagnoli, F., Falugi, F., Bottomley, M., Grandi, G., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-07-25
Release date:2011-08-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:1.95 Angstrom Resolution Crystal Structure of Epidermin Leader Peptide Processing Serine Protease (EpiP) S393A Mutant from Staphylococcus aureus.
TO BE PUBLISHED
3J63
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UNIFIED ASSEMBLY MECHANISM OF ASC-DEPENDENT INFLAMMASOMES
Descriptor:Apoptosis-associated speck-like protein containing a CARD
Authors:Lu, A., Magupalli, V.G., Ruan, J., Yin, Q., Atianand, M.K., Vos, M., Schroder, G.F., Fitzgerald, K.A., Wu, H., Egelman, E.H.
Deposit date:2013-12-05
Release date:2014-03-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes.
Cell(Cambridge,Mass.), 156, 2014
3QYQ
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1.8 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF A PUTATIVE DEOXYRIBOSE-PHOSPHATE ALDOLASE FROM TOXOPLASMA GONDII ME49
Descriptor:Deoxyribose-phosphate aldolase, putative, SUCROSE, ...
Authors:Halavaty, A.S., Ruan, J., Minasov, G., Shuvalova, L., Ueno, A., Igarashi, M., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-03-03
Release date:2011-03-30
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional divergence of the aldolase fold in Toxoplasma gondii.
J.Mol.Biol., 427, 2015
3SB1
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HYDROGENASE EXPRESSION PROTEIN HUPH FROM THIOBACILLUS DENITRIFICANS ATCC 25259
Descriptor:hydrogenase expression protein, GLYCEROL, TRIETHYLENE GLYCOL
Authors:Filippova, E.V., Minasov, G., Shuvalova, L., Kiryukhina, O., Ruan, J., Leo, R.D., Joachimiak, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)
Deposit date:2011-06-03
Release date:2011-07-06
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Hydrogenase expression protein HupH from Thiobacillus denitrificans ATCC 25259
To be Published
4D2J
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CRYSTAL STRUCTURE OF F16BP ALDOLASE FROM TOXOPLASMA GONDII (TGALD1)
Descriptor:FRUCTOSE-BISPHOSPHATE ALDOLASE, BETA-MERCAPTOETHANOL, SULFATE ION, ...
Authors:Tonkin, M.L., Ramaswamy, R., Halavaty, A.S., Ruan, J., Igarashi, M., Ngo, H.M., Boulanger, M.J.
Deposit date:2014-05-09
Release date:2014-10-15
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and Functional Divergence of the Aldolase Fold in Toxoplasma Gondii.
J.Mol.Biol., 427, 2015
4EIV
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1.37 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF APO-FORM OF A PUTATIVE DEOXYRIBOSE-PHOSPHATE ALDOLASE FROM TOXOPLASMA GONDII ME49
Descriptor:Deoxyribose-phosphate aldolase, CHLORIDE ION, BETA-MERCAPTOETHANOL
Authors:Halavaty, A.S., Ruan, J., Minasov, G., Shuvalova, L., Ueno, A., Igarashi, M., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-04-05
Release date:2012-05-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Structural and Functional Divergence of the Aldolase Fold in Toxoplasma gondii.
J.Mol.Biol., 427, 2015
4FBD
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2.35 ANGSTROM CRYSTAL STRUCTURE OF CONSERVED HYPOTHETICAL PROTEIN FROM TOXOPLASMA GONDII ME49.
Descriptor:Putative uncharacterized protein
Authors:Minasov, G., Ruan, J., Wawrzak, Z., Shuvalova, L., Ngo, H., Knoll, L., Milligan-Myhre, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-05-22
Release date:2012-07-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:2.35 Angstrom Crystal Structure of Conserved Hypothetical Protein from Toxoplasma gondii ME49.
TO BE PUBLISHED
4IR8
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1.85 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE SEDOHEPTULOSE-1,7 BISPHOSPHATASE FROM TOXOPLASMA GONDII
Descriptor:Sedoheptulose-1,7 bisphosphatase, putative, DI(HYDROXYETHYL)ETHER, ...
Authors:Minasov, G., Ruan, J., Wawrzak, Z., Halavaty, A., Shuvalova, L., Harb, O.S., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-01-14
Release date:2013-01-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:1.85 Angstrom Crystal Structure of Putative Sedoheptulose-1,7 bisphosphatase from Toxoplasma gondii.
TO BE PUBLISHED
4MJZ
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2.75 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF PUTATIVE OROTIDINE-MONOPHOSPHATE-DECARBOXYLASE FROM TOXOPLASMA GONDII.
Descriptor:Orotidine 5'-phosphate decarboxylase, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ...
Authors:Minasov, G., Wawrzak, Z., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-09-04
Release date:2013-09-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:2.75 Angstrom Resolution Crystal Structure of Putative Orotidine-monophosphate-decarboxylase from Toxoplasma gondii.
TO BE PUBLISHED
4NML
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2.60 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF PUTATIVE RIBOSE 5-PHOSPHATE ISOMERASE FROM TOXOPLASMA GONDII ME49 IN COMPLEX WITH DL-MALIC ACID
Descriptor:Ribulose 5-phosphate isomerase, CHLORIDE ION, D-MALATE
Authors:Halavaty, A.S., Dubrovska, I., Flores, K., Shanmugam, D., Shuvalova, L., Roos, D., Ruan, J., Ngo, H., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-11-15
Release date:2013-12-04
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from Toxoplasma gondii ME49 in complex with DL-Malic acid
To be Published
4NOG
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CRYSTAL STRUCTURE OF A PUTATIVE ORNITHINE AMINOTRANSFERASE FROM TOXOPLASMA GONDII ME49 IN COMPLEX WITH PYRODOXAL-5'-PHOSPHATE
Descriptor:Putative ornithine aminotransferase, mitochondrial, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Filippova, E.V., Halavaty, A., Ruan, J., Shuvalova, L., Flores, K., Dubrovska, I., Ngo, H., Shanmugam, D., Roos, D., Anderson, W.F., Center for Structural Genomics of Infectious Diseases, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-11-19
Release date:2013-12-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of a putative ornithine aminotransferase from Toxoplasma gondii ME49 in complex with pyrodoxal-5'-phosphate
To be Published
4NU7
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2.05 ANGSTROM CRYSTAL STRUCTURE OF RIBULOSE-PHOSPHATE 3-EPIMERASE FROM TOXOPLASMA GONDII.
Descriptor:Ribulose-phosphate 3-epimerase, CHLORIDE ION, ZINC ION, ...
Authors:Minasov, G., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Flores, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-12-03
Release date:2013-12-18
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:2.05 Angstrom Crystal Structure of Ribulose-phosphate 3-epimerase from Toxoplasma gondii.
TO BE PUBLISHED
4O0N
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2.4 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF PUTATIVE NUCLEOSIDE DIPHOSPHATE KINASE FROM TOXOPLASMA GONDII.
Descriptor:Nucleoside diphosphate kinase, SULFATE ION
Authors:Minasov, G., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Flores, K., Shanmugam, D., Roos, D., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-12-13
Release date:2013-12-25
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:2.4 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii.
TO BE PUBLISHED
4ODI
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2.6 ANGSTROM CRYSTAL STRUCTURE OF PUTATIVE PHOSPHOGLYCERATE MUTASE 1 FROM TOXOPLASMA GONDII
Descriptor:Phosphoglycerate mutase PGMII, SODIUM ION
Authors:Minasov, G., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Flores, K., Shanmugam, D., Roos, D., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-01-10
Release date:2014-01-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:2.6 Angstrom Crystal Structure of Putative Phosphoglycerate Mutase 1 from Toxoplasma gondii.
TO BE PUBLISHED
5BXI
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1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF PUTATIVE NUCLEOSIDE DIPHOSPHATE KINASE FROM TOXOPLASMA GONDII WITH TYROSINE OF TAG BOUND TO ACTIVE SITE
Descriptor:Nucleoside diphosphate kinase, BICARBONATE ION, DI(HYDROXYETHYL)ETHER
Authors:Minasov, G., Ruan, J., Ngo, H., Shuvalova, L., Dubrovska, I., Flores, K., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-06-09
Release date:2015-06-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:1.7 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii with Tyrosine of Tag Bound to Active Site.
To Be Published
5H8D
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CRYSTAL STRUCTURE OF AN ASC BINDING NANOBODY
Descriptor:VHH nanobody
Authors:Lu, A., Schmidt, F.I., Ruan, J., Tang, C., Wu, H., Ploegh, H.L.
Deposit date:2015-12-23
Release date:2016-04-06
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly.
J.Exp.Med., 213, 2016
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