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5ACN
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STRUCTURE OF ACTIVATED ACONITASE. FORMATION OF THE (4FE-4S) CLUSTER IN THE CRYSTAL
分子名称:ACONITASE, SULFATE ION, FE3-S4 CLUSTER, ...
著者Robbins, A.H., Stout, C.D.
登録日1990-01-16
公開日1990-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of activated aconitase: formation of the [4Fe-4S] cluster in the crystal.
Proc.Natl.Acad.Sci.USA, 86, 1989
6ACN
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STRUCTURE OF ACTIVATED ACONITASE. FORMATION OF THE (4FE-4S) CLUSTER IN THE CRYSTAL
分子名称:ACONITASE, SULFATE ION, IRON/SULFUR CLUSTER, ...
著者Robbins, A.H., Stout, C.D.
登録日1990-01-16
公開日1990-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of activated aconitase: formation of the [4Fe-4S] cluster in the crystal.
Proc.Natl.Acad.Sci.USA, 86, 1989
3F9Q
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RE-REFINEMENT OF UNCOMPLEXED PLASMEPSIN II FROM PLASMODIUM FALCIPARUM.
分子名称:Plasmepsin-2
著者Robbins, A.H., Mckenna, R.
登録日2008-11-14
公開日2009-03-10
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data Bank.
Acta Crystallogr.,Sect.D, 65, 2009
3MWO
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HUMAN CARBONIC ANHYDRASE II IN A DOUBLED MONOCLINIC CELL: A RE-DETERMINATION
分子名称:Carbonic anhydrase 2, ZINC ION
著者Robbins, A.H., McKenna, R.
登録日2010-05-06
公開日2010-06-09
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Emerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinic P2(1) with a doubled a axis.
Acta Crystallogr.,Sect.D, 66, 2010
4MT2
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COMPARISON OF THE NMR SOLUTION STRUCTURE AND THE X-RAY CRYSTAL STRUCTURE OF RAT METALLOTHIONEIN-2
分子名称:METALLOTHIONEIN ISOFORM II, CADMIUM ION, ZINC ION, ...
著者Robbins, A.H., Stout, C.D.
登録日1993-02-26
公開日1993-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
Proc.Natl.Acad.Sci.USA, 89, 1992
3HS4
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HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH ACETAZOLAMIDE
分子名称:Carbonic anhydrase 2, ZINC ION, GLYCEROL, ...
著者Robbins, A.H., Genis, C., Domsic, J., Sippel, K.H., Agbandje-McKenna, M., McKenna, R.
登録日2009-06-10
公開日2009-12-08
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug design.
Acta Crystallogr.,Sect.F, 65, 2009
3EKI
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STRUCTURAL INSIGHTS OF THE MYCOPLASMA HYORHINIS PROTEIN MH-P37: A PUTATIVE THIAMINE PYROPHOSPHATE TRANSPORTER
分子名称:High affinity transport system protein p37, THIAMINE DIPHOSPHATE, GLYCEROL, ...
著者Sippel, K.H., Robbins, A.H., Reutzel, R., McKenna, R.
登録日2008-09-19
公開日2009-06-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis
J.Bacteriol., 191, 2009
1KTE
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CRYSTAL STRUCTURE OF THIOLTRANSFERASE AT 2.2 ANGSTROM RESOLUTION
分子名称:THIOLTRANSFERASE
著者Katti, S.K., Robbins, A.H.
登録日1996-02-15
公開日1996-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of thioltransferase at 2.2 A resolution.
Protein Sci., 4, 1995
2R5P
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CRYSTAL STRUCTURE ANALYSIS OF HIV-1 SUBTYPE C PROTEASE COMPLEXED WITH INDINAVIR
分子名称:Protease, CHLORIDE ION, SODIUM ION, ...
著者Coman, R.M., Robbins, A.H., McKenna, R., Dunn, B.M.
登録日2007-09-04
公開日2007-11-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Contribution of Naturally Occurring Polymorphisms in Altering the Biochemical and Structural Characteristics of HIV-1 Subtype C Protease
Biochemistry, 47, 2008
2R5Q
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CRYSTAL STRUCTURE ANALYSIS OF HIV-1 SUBTYPE C PROTEASE COMPLEXED WITH NELFINAVIR
分子名称:Protease, 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE
著者Coman, R.M., Robbins, A.H., McKenna, R., Dunn, B.M.
登録日2007-09-04
公開日2007-11-20
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Contribution of Naturally Occurring Polymorphisms in Altering the Biochemical and Structural Characteristics of HIV-1 Subtype C Protease
Biochemistry, 47, 2008
2R8N
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STRUCTURAL ANALYSIS OF THE UNBOUND FORM OF HIV-1 SUBTYPE C PROTEASE
分子名称:Pol protein, GLYCEROL
著者Coman, R.M., Robbins, A.H., McKenna, R., Dunn, B.M.
登録日2007-09-11
公開日2008-07-29
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献High-resolution structure of unbound human immunodeficiency virus 1 subtype C protease: implications of flap dynamics and drug resistance.
Acta Crystallogr.,Sect.D, 64, 2008
2R9B
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STRUCTURAL ANALYSIS OF PLASMEPSIN 2 FROM PLASMODIUM FALCIPARUM COMPLEXED WITH A PEPTIDE-BASED INHIBITOR
分子名称:Plasmepsin-2, peptide-based inhibitor
著者Liu, P., Marzahn, M.R., Robbins, A.H., McKenna, R., Dunn, B.M.
登録日2007-09-12
公開日2007-11-27
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Recombinant plasmepsin 1 from the human malaria parasite plasmodium falciparum: enzymatic characterization, active site inhibitor design, and structural analysis.
Biochemistry, 48, 2009
3E78
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STRUCTURE DETERMINATION OF THE CANCER-ASSOCIATED MYCOPLASMA HYORHINIS PROTEIN MH-P37
分子名称:High affinity transport system protein p37, THIAMINE DIPHOSPHATE, CALCIUM ION, ...
著者Sippel, K.H., Robbins, A.H., Reutzel, R., Domsic, J., McKenna, R.
登録日2008-08-18
公開日2008-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr.,Sect.D, 64, 2008
3E79
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STRUCTURE DETERMINATION OF THE CANCER-ASSOCIATED MYCOPLASMA HYORHINIS PROTEIN MH-P37
分子名称:High affinity transport system protein p37, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, THIAMINE DIPHOSPHATE, ...
著者Sippel, K.H., Robbins, A.H., Reutzel, R., Domsic, J., McKenna, R.
登録日2008-08-18
公開日2008-10-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37.
Acta Crystallogr.,Sect.D, 64, 2008
3ML2
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HUMAN CARBONIC ANHYDSASE II IN COMPLEX WITH AN ARYL SULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, 2-(7-methoxy-2-oxo-2H-chromen-4-yl)-N-(4-sulfamoylphenyl)acetamide, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., Mckenna, R.
登録日2010-04-16
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations.
Bioorg.Med.Chem., 18, 2010
3MMF
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A 1,3,5-TRIAZINE-SUBSTITUTED BENZENESULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, 4-({4-chloro-6-[(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)benzenesulfonamide, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., Mckenna, R.
登録日2010-04-19
公開日2011-04-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
Bioorg.Med.Chem., 19, 2011
3MNA
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THE CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A 1,3,5-TRIAZINE-SUBSTITUTED BENZENESULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, methyl N-{4-chloro-6-[(4-sulfamoylphenyl)amino]-1,3,5-triazin-2-yl}glycinate, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., Mckenna, R.
登録日2010-04-21
公開日2011-04-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
Bioorg.Med.Chem., 19, 2011
3MZC
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HUMAN CARBONIC AHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, 4-[(cyclopentylcarbamoyl)amino]benzenesulfonamide, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., Mckenna, R.
登録日2010-05-12
公開日2011-03-09
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chem.Commun.(Camb.), 46, 2010
3N0N
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, 4-{[(pentafluorophenyl)carbamoyl]amino}benzenesulfonamide, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., McKenna, R.
登録日2010-05-14
公開日2011-03-16
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chem.Commun.(Camb.), 46, 2010
3N2P
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, 4-{[(3-nitrophenyl)carbamoyl]amino}benzenesulfonamide, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., McKenna, R.
登録日2010-05-18
公開日2011-03-09
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.648 Å)
主引用文献Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chem.Commun.(Camb.), 46, 2010
3N3J
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, GLYCEROL, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., McKenna, R.
登録日2010-05-20
公開日2011-03-09
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chem.Commun.(Camb.), 46, 2010
3N4B
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A BENZENESULFONAMIDE INHIBITOR
分子名称:Carbonic anhydrase 2, ZINC ION, 4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide, ...
著者Avvaru, B.S., Wagner, J., Robbins, A.H., McKenna, R.
登録日2010-05-21
公開日2011-03-09
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chem.Commun.(Camb.), 46, 2010
3OIK
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HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3,17-O,O-BIS-SULFAMATE
分子名称:Carbonic anhydrase 2, ZINC ION, (9BETA,13ALPHA,14BETA,17ALPHA)-2-ETHYLESTRA-1(10),2,4-TRIENE-3,17-DIYL DISULFAMATE, ...
著者Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
登録日2010-08-19
公開日2011-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OIL
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HUMAN CARBONIC ANHYDRASE II MUTANT A65S, N67Q (CA IX MIMIC) BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE
分子名称:Carbonic anhydrase 2, ZINC ION, (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate
著者Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
登録日2010-08-19
公開日2011-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
3OIM
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HUMAN CARBONIC ANHYDRASE II BOUND BY 2-ETHYLESTRADIOL 3-O-SULFAMATE
分子名称:Carbonic anhydrase 2, ZINC ION, (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate, ...
著者Sippel, K.H., Stander, B.A., Robbins, A.H., Tu, C.K., Agbandje-McKenna, M., Silverman, D.N., Joubert, A.M., McKenna, R.
登録日2010-08-19
公開日2011-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds
LETT.DRUG DES.DISCOVERY, 8, 2011
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