2R5P

Crystal Structure Analysis of HIV-1 Subtype C Protease Complexed with Indinavir

Summary for 2R5P

• Entry DOI: 10.2210/pdb2r5p/pdb
• Related: 2R5Q
• Descriptor: Protease, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: hiv-1 subtype c, aspartyl protease, hydrolase, protease, viral protein
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 4
• Total formula weight: 44399.53

Authors

Coman, R.M.,Robbins, A.H.,McKenna, R.,Dunn, B.M. (deposition date: 2007-09-04, release date: 2007-11-20, Last modification date: 2024-02-21)

• Primary citation: Coman, R.M.,Robbins, A.H.,Fernandez, M.A.,Gilliland, C.T.,Sochet, A.A.,Goodenow, M.M.,McKenna, R.,Dunn, B.M.; The Contribution of Naturally Occurring Polymorphisms in Altering the Biochemical and Structural Characteristics of HIV-1 Subtype C Protease; Biochemistry, 47:731-743, 2008; PubMed: 18092815; DOI: 10.1021/bi7018332

Experimental method

X-RAY DIFFRACTION (2.3 Å)