Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 420 |
| Chain | Residue |
| A | GLY73 |
| A | THR74 |
| A | ASN88 |
| A | HOH592 |
| D | ARG41 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 421 |
| Chain | Residue |
| B | THR74 |
| B | ASN88 |
| B | HOH490 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 422 |
| Chain | Residue |
| C | THR74 |
| C | ASN88 |
| B | ARG41 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 423 |
| Chain | Residue |
| D | GLY73 |
| D | THR74 |
| D | ASN88 |
| D | HOH449 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 552 |
| Chain | Residue |
| A | ARG8 |
| A | PRO9 |
| B | THR26 |
| B | GLY27 |
| B | ARG87 |
| B | HOH402 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE MK1 B 902 |
| Chain | Residue |
| A | ARG8 |
| A | LEU23 |
| A | ASP25 |
| A | GLY27 |
| A | GLY48 |
| A | GLY49 |
| A | VAL82 |
| A | ILE84 |
| B | ASP25 |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | GLY48 |
| B | GLY49 |
| B | PRO81 |
| B | ILE84 |
| B | HOH402 |
| B | HOH436 |
| B | HOH437 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE MK1 D 902 |
| Chain | Residue |
| C | ARG8 |
| C | LEU23 |
| C | ASP25 |
| C | GLY27 |
| C | GLY48 |
| C | GLY49 |
| C | VAL82 |
| C | ILE84 |
| D | ASP25 |
| D | GLY27 |
| D | ALA28 |
| D | ASP29 |
| D | ASP30 |
| D | GLY48 |
| D | GLY49 |
| D | PRO81 |
| D | ILE84 |
| D | HOH435 |
| D | HOH488 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| C | ASP25 | |
| D | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
| C | PHE99 | |
| D | PHE99 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | ASP25 | |
| B | THR26 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| C | ASP25 | |
| C | THR26 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| D | ASP25 | |
| D | THR26 | |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | ASP25 | |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| C | ASP25 | |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| D | ASP25 | |
