2R9B
Structural Analysis of Plasmepsin 2 from Plasmodium falciparum complexed with a peptide-based inhibitor
Summary for 2R9B
Entry DOI | 10.2210/pdb2r9b/pdb |
Related PRD ID | PRD_000306 |
Descriptor | Plasmepsin-2, peptide-based inhibitor (3 entities in total) |
Functional Keywords | beta fold aspartyl protease, glycoprotein, vacuole, zymogen, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Plasmodium falciparum More |
Cellular location | Vacuole: P46925 |
Total number of polymer chains | 4 |
Total formula weight | 75839.86 |
Authors | Liu, P.,Marzahn, M.R.,Robbins, A.H.,McKenna, R.,Dunn, B.M. (deposition date: 2007-09-12, release date: 2007-11-27, Last modification date: 2023-11-15) |
Primary citation | Liu, P.,Marzahn, M.R.,Robbins, A.H.,Gutierrez-de-Teran, H.,Rodriguez, D.,McClung, S.H.,Stevens, S.M.,Yowell, C.A.,Dame, J.B.,McKenna, R.,Dunn, B.M. Recombinant plasmepsin 1 from the human malaria parasite plasmodium falciparum: enzymatic characterization, active site inhibitor design, and structural analysis. Biochemistry, 48:4086-4099, 2009 Cited by PubMed: 19271776DOI: 10.1021/bi802059r PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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