Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR CHAIN C OF PEPTIDE-BASED INHIBITOR |
| Chain | Residue |
| A | ILE32 |
| A | SER79 |
| A | THR114 |
| A | ILE123 |
| A | LEU131 |
| A | TYR192 |
| A | GLY216 |
| A | THR217 |
| A | SER218 |
| A | ILE290 |
| A | PHE294 |
| A | ASP34 |
| A | HOH350 |
| B | HIS189 |
| B | PRO295 |
| A | GLY36 |
| A | SER37 |
| A | ALA38 |
| A | MET75 |
| A | ASN76 |
| A | TYR77 |
| A | VAL78 |
| site_id | AC2 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR CHAIN D OF PEPTIDE-BASED INHIBITOR |
| Chain | Residue |
| A | HIS189 |
| A | PRO295 |
| B | ILE32 |
| B | ASP34 |
| B | GLY36 |
| B | SER37 |
| B | ALA38 |
| B | MET75 |
| B | ASN76 |
| B | TYR77 |
| B | VAL78 |
| B | SER79 |
| B | PHE111 |
| B | THR114 |
| B | ILE123 |
| B | LEU131 |
| B | TYR192 |
| B | GLY216 |
| B | THR217 |
| B | SER218 |
| B | ILE290 |
| B | PHE294 |
| D | HOH909 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE31-VAL42 | |
| A | CYS211-VAL222 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| B | ASP34 | |
| B | ASP214 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| A | THR217 | |
| site_id | CSA10 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | THR35 | |
| B | ASP214 | |
| B | THR217 | |
| site_id | CSA11 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| site_id | CSA12 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| site_id | CSA13 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP214 | |
| site_id | CSA14 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP214 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | ASP214 | |
| B | SER37 | |
| B | THR217 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | SER215 | |
| A | ASP34 | |
| A | THR35 | |
| A | ASP214 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | SER215 | |
| B | ASP34 | |
| B | THR35 | |
| B | ASP214 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | ASP214 | |
| B | SER37 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | ASP214 | |
| A | SER37 | |
| A | TYR77 | |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| B | ASP34 | |
| B | ASP214 | |
| B | SER37 | |
| B | TYR77 | |
| site_id | CSA9 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1am5 |
| Chain | Residue | Details |
| A | ASP34 | |
| A | THR35 | |
| A | ASP214 | |
| A | THR217 | |
