3OKU
Human Carbonic Anhydrase II in complex with 2-Ethylestrone-3-O-sulfamate
Summary for 3OKU
Entry DOI | 10.2210/pdb3oku/pdb |
Related | 3IOK 3IOL 3IOM 3OKV |
Descriptor | Carbonic anhydrase 2, ZINC ION, (9beta)-2-ethyl-17-oxoestra-1(10),2,4-trien-3-yl sulfamate, ... (6 entities in total) |
Functional Keywords | mixed alpha/beta fold, reversible hydration of carbon dioxide to bicarbonate, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29902.20 |
Authors | Sippel, K.H.,Stander, B.A.,Robbins, A.H.,Tu, C.K.,Agbandje-McKenna, M.,Silverman, D.N.,Joubert, A.M.,McKenna, R. (deposition date: 2010-08-25, release date: 2011-07-06, Last modification date: 2023-09-06) |
Primary citation | Sippel, K.H.,Stander, B.A.,Robbins, A.H.,Tu, C.K.,Agbandje-McKenna, M.,Silverman, D.N.,Joubert, A.M.,McKenna, R. Characterization of Carbonic Anhydrase Isozyme Specific Inhibition by Sulfamated 2-Ethylestra Compounds LETT.DRUG DES.DISCOVERY, 8:-, 2011 |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
Download full validation report