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8U27
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BU of 8u27 by Molmil
Bcl-2-xL complexed with compound 35
Descriptor: Apoptosis regulator Bcl-2, Bcl-2-like protein 1 chimera, propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate
Authors:Rizo, J, Pan, Y.-Z.
Deposit date:2023-09-05
Release date:2023-09-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insights for selective disruption of Beclin 1 binding to Bcl-2.
Commun Biol, 6, 2023
7UDB
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BU of 7udb by Molmil
Cryo-EM structure of a synaptobrevin-Munc18-1-syntaxin-1 complex class 2
Descriptor: Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1
Authors:Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X.
Deposit date:2022-03-18
Release date:2022-04-06
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex.
Sci Adv, 8, 2022
7UDC
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BU of 7udc by Molmil
cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex class1
Descriptor: Synaptobrevin-2, Syntaxin-1A, Syntaxin-binding protein 1
Authors:Rizo, J, Bai, X, Stepien, K.P, Xu, J, Zhang, X.
Deposit date:2022-03-18
Release date:2022-04-06
Last modified:2022-07-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:SNARE assembly enlightened by cryo-EM structures of a synaptobrevin-Munc18-1-syntaxin-1 complex.
Sci Adv, 8, 2022
4QT7
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BU of 4qt7 by Molmil
Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein
Descriptor: NS5A, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-07-07
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus.
J.Struct.Biol., 189, 2015
4OMO
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BU of 4omo by Molmil
Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OML
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BU of 4oml by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128R
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OMN
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BU of 4omn by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128E
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OMP
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BU of 4omp by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
2A20
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BU of 2a20 by Molmil
Solution structure of Rim2 Zinc Finger Domain
Descriptor: Regulating synaptic membrane exocytosis protein 2, ZINC ION
Authors:Dulubova, I, Lou, X, Lu, J, Huryeva, I, Alam, A, Schneggenburger, R, Sudhof, T.C, Rizo, J.
Deposit date:2005-06-21
Release date:2005-08-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?
Embo J., 24, 2005
4Y21
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BU of 4y21 by Molmil
Crystal Structure of Munc13-1 MUN domain
Descriptor: Protein unc-13 homolog A
Authors:Yang, X.Y, Wang, S, Sheng, Y, Zhang, M, Zou, W.J, Wu, L.J, Kang, L.J, Rizo, J, Zhang, R.G, Xu, T, Ma, C.
Deposit date:2015-02-09
Release date:2015-06-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Syntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle priming.
Nat.Struct.Mol.Biol., 22, 2015
2A4H
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BU of 2a4h by Molmil
Solution structure of Sep15 from Drosophila melanogaster
Descriptor: Selenoprotein Sep15
Authors:Ferguson, A.D, Labunskyy, V.M, Fomenko, D.E, Chelliah, Y, Amezcua, C.A, Rizo, J, Gladyshev, V.N, Deisenhofer, J.
Deposit date:2005-06-28
Release date:2005-12-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family.
J.Biol.Chem., 281, 2006
2A2P
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BU of 2a2p by Molmil
Solution structure of SelM from Mus musculus
Descriptor: Selenoprotein M
Authors:Ferguson, A.D, Labunskyy, V.M, Fomenko, D.E, Chelliah, Y, Amezcua, C.A, Rizo, J, Gladyshev, V.N, Deisenhofer, J.
Deposit date:2005-06-22
Release date:2005-12-06
Last modified:2021-10-20
Method:SOLUTION NMR
Cite:NMR Structures of the Selenoproteins Sep15 and SelM Reveal Redox Activity of a New Thioredoxin-like Family.
J.Biol.Chem., 281, 2006
5UF7
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BU of 5uf7 by Molmil
CRYSTAL STRUCTURE OF MUNC13-1 MUN DOMAIN
Descriptor: Protein unc-13 homolog A
Authors:Tomchick, D.R, Rizo, J, Xu, J.
Deposit date:2017-01-03
Release date:2017-02-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.896 Å)
Cite:Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
Elife, 6, 2017
5UE8
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BU of 5ue8 by Molmil
The crystal structure of Munc13-1 C1C2BMUN domain
Descriptor: CHLORIDE ION, Protein unc-13 homolog A, ZINC ION
Authors:Tomchick, D.R, Rizo, J, Xu, J.
Deposit date:2016-12-29
Release date:2017-02-15
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.
Elife, 6, 2017
2CJT
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BU of 2cjt by Molmil
Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, UNC-13 HOMOLOG A
Authors:Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J.
Deposit date:2006-04-06
Release date:2006-06-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structural Basis for a Munc13-1 Dimeric to Munc13-1/Rim Heterodimer Switch
Plos Biol., 4, 2006
2CJS
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BU of 2cjs by Molmil
Structural Basis for a Munc13-1 Homodimer - Munc13-1 - RIM Heterodimer Switch: C2-domains as Versatile Protein-Protein Interaction Modules
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, ...
Authors:Lu, J, Machius, M, Dulubova, I, Dai, H, Sudhof, T.C, Tomchick, D.R, Rizo, J.
Deposit date:2006-04-06
Release date:2006-06-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch.
Plos Biol., 4, 2006
2KXV
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BU of 2kxv by Molmil
NMR structure and calcium-binding properties of the tellurite resistance protein TerD from Klebsiella pneumoniae
Descriptor: CALCIUM ION, Tellurite resistance protein
Authors:Pan, Y.R, Lou, Y.C, Rizo, J, Chen, C.
Deposit date:2010-05-13
Release date:2010-12-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR Structure and Calcium-Binding Properties of the Tellurite Resistance Protein TerD from Klebsiella pneumoniae
J.Mol.Biol., 2010
2KXT
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BU of 2kxt by Molmil
NMR structure and calcium-binding properties of the tellurite resistance protein TerD from Klebsiella pneumoniae
Descriptor: Tellurite resistance protein
Authors:Pan, Y.R, Lou, Y.C, Rizo, J, Chen, C.
Deposit date:2010-05-12
Release date:2010-12-22
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR Structure and Calcium-Binding Properties of the Tellurite Resistance Protein TerD from Klebsiella pneumoniae
J.Mol.Biol., 2010
6ANJ
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BU of 6anj by Molmil
Synaptotagmin-7, C2A domain
Descriptor: ACETATE ION, CALCIUM ION, Synaptotagmin-7, ...
Authors:Tomchick, D.R, Rizo, J, Voleti, R.
Deposit date:2017-08-13
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ANK
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BU of 6ank by Molmil
Synaptotagmin-7, C2A- and C2B-domains
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, Synaptotagmin-7
Authors:Tomchick, D.R, Rizo, J, Voleti, R.
Deposit date:2017-08-13
Release date:2017-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.254 Å)
Cite:Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3SWH
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BU of 3swh by Molmil
Munc13-1, MUN domain, C-terminal module
Descriptor: Protein unc-13 homolog A
Authors:Tomchick, D.R, Rizo, J, Li, W.
Deposit date:2011-07-13
Release date:2011-11-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering Factors.
Structure, 19, 2011
1BR0
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BU of 1br0 by Molmil
THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A
Descriptor: PROTEIN (SYNTAXIN 1-A)
Authors:Fernandez, I, Ubach, J, Dubulova, I, Zhang, X, Sudhof, T.C, Rizo, J.
Deposit date:1998-08-25
Release date:1998-09-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A.
Cell(Cambridge,Mass.), 94, 1998
1S2H
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BU of 1s2h by Molmil
The Mad2 spindle checkpoint protein possesses two distinct natively folded states
Descriptor: Mitotic spindle assembly checkpoint protein MAD2A
Authors:Luo, X, Tang, Z, Xia, G, Wassmann, K, Matsumoto, T, Rizo, J, Yu, H.
Deposit date:2004-01-08
Release date:2004-03-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The Mad2 spindle checkpoint protein has two distinct natively folded states.
Nat.Struct.Mol.Biol., 11, 2004
2Q3X
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BU of 2q3x by Molmil
The RIM1alpha C2B domain
Descriptor: CHLORIDE ION, Regulating synaptic membrane exocytosis protein 1, SODIUM ION, ...
Authors:Guan, R, Dai, H, Tomchick, D.R, Machius, M, Sudhof, T.C, Rizo, J.
Deposit date:2007-05-30
Release date:2007-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Crystal Structure of the RIM1alpha C(2)B Domain at 1.7 A Resolution.
Biochemistry, 46, 2007
2BWQ
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BU of 2bwq by Molmil
Crystal Structure of the RIM2 C2A-domain at 1.4 angstrom Resolution
Descriptor: REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2, SULFATE ION
Authors:Dai, H, Tomchick, D.R, Garcia, J, Sudhof, T.C, Machius, M, Rizo, J.
Deposit date:2005-07-15
Release date:2005-10-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal Structure of the Rim2 C(2)A-Domain at 1.4 A Resolution.
Biochemistry, 44, 2005

 

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