Author results

5FTJ
  • Download 5ftj
  • View 5ftj
Molmil generated image of 5ftj
CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO UPCDC30245 INHIBITOR
分子名称:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE, 1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE
著者Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTK
  • Download 5ftk
  • View 5ftk
Molmil generated image of 5ftk
CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ADP
分子名称:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE
著者Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTL
  • Download 5ftl
  • View 5ftl
Molmil generated image of 5ftl
CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION I)
分子名称:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, ADENOSINE-5'-DIPHOSPHATE
著者Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTM
  • Download 5ftm
  • View 5ftm
Molmil generated image of 5ftm
CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION II)
分子名称:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ADENOSINE-5'-DIPHOSPHATE, ...
著者Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTN
  • Download 5ftn
  • View 5ftn
Molmil generated image of 5ftn
CRYO-EM STRUCTURE OF HUMAN P97 BOUND TO ATPGS (CONFORMATION III)
分子名称:TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION
著者Banerjee, S., Bartesaghi, A., Merk, A., Rao, P., Bulfer, S.L., Yan, Y., Green, N., Mroczkowski, B., Neitz, R.J., Wipf, P., Falconieri, V., Deshaies, R.J., Milne, J.L.S., Huryn, D., Arkin, M., Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2018-10-03
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
1ONJ
  • Download 1onj
  • View 1onj
Molmil generated image of 1onj
CRYSTAL STRUCTURE OF ATRATOXIN-B FROM CHINESE COBRA VENOM OF NAJA ATRA
分子名称:Cobrotoxin b, SULFATE ION
著者Lou, X., Tu, X., Pan, G., Xu, C., Fan, R., Lu, W., Deng, W., Rao, P., Teng, M., Niu, L.
登録日2003-02-28
公開日2004-02-28
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.555 Å)
主引用文献Purification, N-terminal sequencing, crystallization and preliminary structural determination of atratoxin-b, a short-chain alpha-neurotoxin from Naja atra venom.
Acta Crystallogr.,Sect.D, 59, 2003
3JCZ
  • Download 3jcz
  • View 3jcz
Molmil generated image of 3jcz
STRUCTURE OF BOVINE GLUTAMATE DEHYDROGENASE IN THE UNLIGANDED STATE
分子名称:Glutamate dehydrogenase 1, mitochondrial
著者Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
登録日2016-03-27
公開日2016-04-27
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD0
  • Download 3jd0
  • View 3jd0
Molmil generated image of 3jd0
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH GTP
分子名称:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE
著者Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
登録日2016-03-28
公開日2016-04-27
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD1
  • Download 3jd1
  • View 3jd1
Molmil generated image of 3jd1
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, CLOSED CONFORMATION
分子名称:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
著者Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
登録日2016-03-28
公開日2016-04-27
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD2
  • Download 3jd2
  • View 3jd2
Molmil generated image of 3jd2
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH, OPEN CONFORMATION
分子名称:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
著者Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
登録日2016-03-28
公開日2016-04-27
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD3
  • Download 3jd3
  • View 3jd3
Molmil generated image of 3jd3
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, OPEN CONFORMATION
分子名称:Glutamate dehydrogenase 1, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
登録日2016-03-28
公開日2016-04-27
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
3JD4
  • Download 3jd4
  • View 3jd4
Molmil generated image of 3jd4
GLUTAMATE DEHYDROGENASE IN COMPLEX WITH NADH AND GTP, CLOSED CONFORMATION
分子名称:Glutamate dehydrogenase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
著者Borgnia, M.J., Banerjee, S., Merk, A., Matthies, D., Bartesaghi, A., Rao, P., Pierson, J., Earl, L.A., Falconieri, V., Subramaniam, S., Milne, J.L.S.
登録日2016-03-28
公開日2016-04-27
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol.Pharmacol., 89, 2016
4UQ6
  • Download 4uq6
  • View 4uq6
Molmil generated image of 4uq6
ELECTRON DENSITY MAP OF GLUA2EM IN COMPLEX WITH LY451646 AND GLUTAMATE
分子名称:GLUTAMATE RECEPTOR 2, GLUTAMIC ACID
著者Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
登録日2014-06-20
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (12.8 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQJ
  • Download 4uqj
  • View 4uqj
Molmil generated image of 4uqj
CRYO-EM DENSITY MAP OF GLUA2EM IN COMPLEX WITH ZK200775
分子名称:GLUTAMATE RECEPTOR 2, {[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid
著者Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (10.4 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQK
  • Download 4uqk
  • View 4uqk
Molmil generated image of 4uqk
ELECTRON DENSITY MAP OF GLUA2EM IN COMPLEX WITH QUISQUALATE AND LY451646
分子名称:GLUTAMATE RECEPTOR 2, (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID
著者Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (16.4 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
4UQQ
  • Download 4uqq
  • View 4uqq
Molmil generated image of 4uqq
ELECTRON DENSITY MAP OF GLUK2 DESENSITIZED STATE IN COMPLEX WITH 2S,4R-4-METHYLGLUTAMATE
分子名称:GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2, GLUTAMIC ACID
著者Meyerson, J.R., Kumar, J., Chittori, S., Rao, P., Pierson, J., Bartesaghi, A., Mayer, M.L., Subramaniam, S.
登録日2014-06-24
公開日2014-08-13
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Structural Mechanism of Glutamate Receptor Activation and Desensitization
Nature, 514, 2014
5K0Z
  • Download 5k0z
  • View 5k0z
Molmil generated image of 5k0z
CRYO-EM STRUCTURE OF LACTATE DEHYDROGENASE (LDH) IN INHIBITOR-BOUND STATE
分子名称:L-lactate dehydrogenase B chain
著者Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
登録日2016-05-17
公開日2016-06-08
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K10
  • Download 5k10
  • View 5k10
Molmil generated image of 5k10
CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1)
分子名称:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
登録日2016-05-17
公開日2016-06-08
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K11
  • Download 5k11
  • View 5k11
Molmil generated image of 5k11
CRYO-EM STRUCTURE OF ISOCITRATE DEHYDROGENASE (IDH1) IN INHIBITOR-BOUND STATE
分子名称:Isocitrate dehydrogenase [NADP] cytoplasmic, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
登録日2016-05-17
公開日2016-06-08
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5K12
  • Download 5k12
  • View 5k12
Molmil generated image of 5k12
CRYO-EM STRUCTURE OF GLUTAMATE DEHYDROGENASE AT 1.8 A RESOLUTION
分子名称:Glutamate dehydrogenase 1, mitochondrial
著者Merk, A., Bartesaghi, A., Banerjee, S., Falconieri, V., Rao, P., Earl, L., Milne, J., Subramaniam, S.
登録日2016-05-17
公開日2016-06-08
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (1.8 Å)
主引用文献Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
5KUF
  • Download 5kuf
  • View 5kuf
Molmil generated image of 5kuf
GLUK2EM WITH 2S,4R-4-METHYLGLUTAMATE
分子名称:Glutamate receptor ionotropic, kainate 2, 2S,4R-4-METHYLGLUTAMATE
著者Meyerson, J.R., Chittori, S., Merk, A., Rao, P., Han, T.H., Serpe, M., Mayer, M.L., Subramaniam, S.
登録日2016-07-13
公開日2016-09-07
最終更新日2017-09-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of kainate subtype glutamate receptor desensitization.
Nature, 537, 2016
5KUH
  • Download 5kuh
  • View 5kuh
Molmil generated image of 5kuh
GLUK2EM WITH LY466195
分子名称:Glutamate receptor ionotropic, kainate 2, (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid
著者Meyerson, J.R., Chittori, S., Merk, A., Rao, P., Han, T.H., Serpe, M., Mayer, M.L., Subramaniam, S.
登録日2016-07-13
公開日2016-09-07
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (11.6 Å)
主引用文献Structural basis of kainate subtype glutamate receptor desensitization.
Nature, 537, 2016
6B44
  • Download 6b44
  • View 6b44
Molmil generated image of 6b44
CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND TARGET DSDNA
分子名称:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
最終更新日2017-12-06
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B45
  • Download 6b45
  • View 6b45
Molmil generated image of 6b45
CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX
分子名称:CRISPR-associated protein Csy1, CRISPR-associated protein Csy2, CRISPR-associated protein Csy3, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
6B46
  • Download 6b46
  • View 6b46
Molmil generated image of 6b46
CRYO-EM STRUCTURE OF TYPE I-F CRISPR CRRNA-GUIDED CSY SURVEILLANCE COMPLEX WITH BOUND ANTI-CRISPR PROTEIN ACRF1
分子名称:CRISPR-associated protein Csy3, Anti-CRISPR protein AcrF1, CRISPR-associated endonuclease Cas6/Csy4, ...
著者Guo, T.W., Bartesaghi, A., Yang, H., Falconieri, V., Rao, P., Merk, A., Fox, T., Earl, L., Patel, D.J., Subramaniam, S.
登録日2017-09-25
公開日2017-10-18
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell, 171, 2017
<12>