5K0Z

Cryo-EM structure of lactate dehydrogenase (LDH) in inhibitor-bound state

Summary for 5K0Z

Entry DOI	10.2210/pdb5k0z/pdb
Related	5K10 5K11 5K12
EMDB information	8191 8192 8193 8194
Descriptor	L-lactate dehydrogenase B chain (2 entities in total)
Functional Keywords	lactate dehydrogenase, small metabolic complex, small molecule inhibitor, oxidoreductase
Biological source	Gallus gallus (Chicken)
Total number of polymer chains	4
Total formula weight	144462.62
Authors	Merk, A.,Bartesaghi, A.,Banerjee, S.,Falconieri, V.,Rao, P.,Earl, L.,Milne, J.,Subramaniam, S. (deposition date: 2016-05-17, release date: 2016-06-08, Last modification date: 2024-03-06)
Primary citation	Merk, A.,Bartesaghi, A.,Banerjee, S.,Falconieri, V.,Rao, P.,Davis, M.I.,Pragani, R.,Boxer, M.B.,Earl, L.A.,Milne, J.L.,Subramaniam, S. Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery. Cell, 165:1698-1707, 2016 Cited by PubMed: 27238019 DOI: 10.1016/j.cell.2016.05.040 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation