3M4A
 
 | | Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site | | Descriptor: | ACETIC ACID, DNA (5'-D(*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*CP*CP*TP*TP*AP*TP*TP*C)-3'), ... | | Authors: | Patel, A, Yakovleva, L, Shuman, S, Mondragon, A. | | Deposit date: | 2010-03-10 | | Release date: | 2010-07-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Crystal structure of a bacterial topoisomerase IB in complex with DNA reveals a secondary DNA binding site.
Structure, 18, 2010
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8GDR
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2F4Q
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6HPR
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7U0Q
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7U0X
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7UOW
 | | SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 034_32 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody 034_32 heavy chain, ... | | Authors: | Patel, A, Ortlund, E. | | Deposit date: | 2022-04-14 | | Release date: | 2023-04-19 | | Last modified: | 2023-09-13 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
Structure, 31, 2023
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3EG6
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7MIA
 | | Maize rayado fino virus protease | | Descriptor: | RNA replication protein | | Authors: | Patel, A, Mark, B.L. | | Deposit date: | 2021-04-16 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase.
J.Biol.Chem., 297, 2021
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7MIC
 | | Maize rayado fino virus protease in complex with Ubiquitin | | Descriptor: | 3-AMINOPROPANE, GLYCEROL, RNA replication protein, ... | | Authors: | Patel, A, Mark, B.L. | | Deposit date: | 2021-04-16 | | Release date: | 2021-07-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase.
J.Biol.Chem., 297, 2021
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5EH2
 | | Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence III | | Descriptor: | DNA (5'-D(*AP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*CP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*G)-3'), Histone-lysine N-methyltransferase PRDM9, ... | | Authors: | Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. | | Deposit date: | 2015-10-27 | | Release date: | 2016-02-17 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for human PRDM9 action at recombination hot spots.
Genes Dev., 30, 2016
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5EI9
 | | Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence I | | Descriptor: | DNA (5'-D(*AP*TP*CP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*GP*GP*A)-3'), Histone-lysine N-methyltransferase PRDM9, ... | | Authors: | Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. | | Deposit date: | 2015-10-29 | | Release date: | 2016-02-17 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.921 Å) | | Cite: | Structural basis for human PRDM9 action at recombination hot spots.
Genes Dev., 30, 2016
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5EGB
 | | Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence II | | Descriptor: | DNA (5'-D(*AP*CP*CP*AP*CP*GP*TP*GP*GP*CP*TP*AP*GP*GP*GP*AP*GP*GP*CP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*GP*CP*CP*TP*CP*CP*CP*TP*AP*GP*CP*CP*AP*CP*GP*TP*GP*G)-3'), Histone-lysine N-methyltransferase PRDM9, ... | | Authors: | Patel, A, Horton, J.R, Wilson, G.G, Zhang, X, Cheng, X. | | Deposit date: | 2015-10-26 | | Release date: | 2016-02-17 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.977 Å) | | Cite: | Structural basis for human PRDM9 action at recombination hot spots.
Genes Dev., 30, 2016
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5V3J
 | | mouseZFP568-ZnF1-10 in complex with DNA | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (26-MER), MAGNESIUM ION, ... | | Authors: | Patel, A, Cheng, X. | | Deposit date: | 2017-03-07 | | Release date: | 2018-03-07 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.064 Å) | | Cite: | DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
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5V3G
 | | PRDM9-allele-C ZnF8-13 | | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*CP*AP*AP*CP*GP*CP*TP*CP*AP*CP*TP*GP*GP*GP*GP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*CP*CP*CP*CP*AP*GP*TP*GP*AP*GP*CP*GP*TP*TP*GP*CP*CP*C)-3'), PR domain zinc finger protein 9, ... | | Authors: | Patel, A, Cheng, X. | | Deposit date: | 2017-03-07 | | Release date: | 2017-08-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.416 Å) | | Cite: | Structural basis of human PR/SET domain 9 (PRDM9) allele C-specific recognition of its cognate DNA sequence.
J. Biol. Chem., 292, 2017
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5V3M
 | | mouseZFP568-ZnF1-11 in complex with DNA | | Descriptor: | DNA (28-MER), ZINC ION, Zinc finger protein 568 | | Authors: | Patel, A, Cheng, X. | | Deposit date: | 2017-03-07 | | Release date: | 2018-03-07 | | Last modified: | 2019-09-18 | | Method: | X-RAY DIFFRACTION (2.091 Å) | | Cite: | DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
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5WJQ
 | | mouseZFP568-ZnF2-11 in complex with DNA | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (28-MER), ZINC ION, ... | | Authors: | Patel, A, Cheng, X. | | Deposit date: | 2017-07-24 | | Release date: | 2018-03-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.794 Å) | | Cite: | DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
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7ZJS
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7U0P
 | | SARS-Cov2 S protein structure in complex with neutralizing monoclonal antibody 002-S21F2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Patel, A, Ortlund, E. | | Deposit date: | 2022-02-18 | | Release date: | 2022-08-10 | | Last modified: | 2023-02-22 | | Method: | ELECTRON MICROSCOPY (3.76 Å) | | Cite: | Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
Sci Adv, 8, 2022
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7UPL
 | | SARS-Cov2 Omicron varient S protein structure in complex with neutralizing monoclonal antibody 002-S21F2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | Authors: | Patel, A, Ortlund, E. | | Deposit date: | 2022-04-15 | | Release date: | 2022-08-10 | | Last modified: | 2023-02-22 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
Sci Adv, 8, 2022
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5VQE
 | | Beta-glucoside phosphorylase BglX bound to 2FGlc | | Descriptor: | 2-deoxy-2-fluoro-alpha-D-glucopyranose, Beta-glucoside phosphorylase BglX | | Authors: | Patel, A, Mark, B.L. | | Deposit date: | 2017-05-08 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.889 Å) | | Cite: | Structural and mechanistic analysis of a beta-glycoside phosphorylase identified by screening a metagenomic library.
J. Biol. Chem., 293, 2018
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5VQD
 | | Beta-glucoside phosphorylase BglX | | Descriptor: | Beta-glucoside phosphorylase BglX, GLYCEROL | | Authors: | Patel, A, Mark, B.L. | | Deposit date: | 2017-05-08 | | Release date: | 2018-01-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and mechanistic analysis of a beta-glycoside phosphorylase identified by screening a metagenomic library.
J. Biol. Chem., 293, 2018
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8UPY
 | | Methanosarcine mazei tRNAPyl in A-site of ribosome | | Descriptor: | RNA (72-MER) | | Authors: | Krahn, N, Zhang, J, Melnikov, S.V, Tharp, J.M, Villa, A, Patel, A, Howard, R.J, Gabir, H, Patel, T.R, Stetefeld, J, Puglisi, J, Soll, D. | | Deposit date: | 2023-10-23 | | Release date: | 2024-09-04 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut.
Nucleic Acids Res., 52, 2024
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4XS7
 | | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis | | Descriptor: | Daunorubicin-doxorubicin polyketide synthase | | Authors: | Jackson, D.R, Valentic, T.R, Tsai, S.C, Patel, A, Mohammed, L, Vasilakis, K, Wattana-amorn, P, Long, P.F, Crump, M.P, Crosby, J. | | Deposit date: | 2015-01-22 | | Release date: | 2016-01-27 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis
To Be Published
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4XSA
 | | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis | | Descriptor: | Daunorubicin-doxorubicin polyketide synthase | | Authors: | Jackson, D.R, Valentic, T.R, Tsai, S.C, Patel, A, Mohammed, L, Vasilakis, K, Wattana-amorn, P, Long, P.F, Crump, M.P, Crosby, J. | | Deposit date: | 2015-01-22 | | Release date: | 2016-01-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.204 Å) | | Cite: | Determining the Molecular Basis for Starter Unit Selection During Daunorubicin Biosynthesis
To Be Published
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