Author results

1OAC
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CRYSTAL STRUCTURE OF A QUINOENZYME: COPPER AMINE OXIDASE OF ESCHERICHIA COLI AT 2 ANGSTROEMS RESOLUTION
Descriptor:COPPER AMINE OXIDASE, COPPER (II) ION, CALCIUM ION
Authors:Parsons, M.R., Convery, M.A., Wilmot, C.M., Phillips, S.E.V.
Deposit date:1995-09-27
Release date:1996-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a quinoenzyme: copper amine oxidase of Escherichia coli at 2 A resolution.
Structure, 3, 1995
2LZ2
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THE THREE DIMENSIONAL STRUCTURE OF TURKEY EGG WHITE LYSOZYME AT 2.2 ANGSTROMS RESOLUTION
Descriptor:TURKEY EGG WHITE LYSOZYME
Authors:Parsons, M.R., Phillips, S.E.V.
Deposit date:1988-10-20
Release date:1989-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Three Dimensional Structure of Turkey Egg White Lysozyme at 2.2 Angstroms Resolution
To be Published
1EFC
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INTACT ELONGATION FACTOR FROM E.COLI
Descriptor:PROTEIN (ELONGATION FACTOR), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Song, H., Parsons, M.R., Rowsell, S., Leonard, G., Phillips, S.E.V.
Deposit date:1998-11-24
Release date:1999-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of intact elongation factor EF-Tu from Escherichia coli in GDP conformation at 2.05 A resolution.
J.Mol.Biol., 285, 1999
1F9N
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CRYSTAL STRUCTURE OF AHRC, THE ARGININE REPRESSOR/ACTIVATOR PROTEIN FROM BACILLUS SUBTILIS
Descriptor:ARGININE REPRESSOR/ACTIVATOR PROTEIN
Authors:Dennis, C.A., Glykos, N.M., Parsons, M.R., Phillips, S.E.V.
Deposit date:2000-07-11
Release date:2002-02-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The structure of AhrC, the arginine repressor/activator protein from Bacillus subtilis.
Acta Crystallogr.,Sect.D, 58, 2002
1GPC
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CORE GP32, DNA-BINDING PROTEIN
Descriptor:PROTEIN (CORE GP32), ZINC ION
Authors:Shamoo, Y., Friedman, A.M., Parsons, M.R., Konigsberg, W.H., Steitz, T.A.
Deposit date:1995-06-01
Release date:1995-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA.
Nature, 376, 1995
1JRQ
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X-RAY STRUCTURE ANALYSIS OF THE ROLE OF THE CONSERVED TYROSINE-369 IN ACTIVE SITE OF E. COLI AMINE OXIDASE
Descriptor:Copper amine oxidase, COPPER (II) ION, CALCIUM ION
Authors:Murray, J.M., Kurtis, C.R., Tambarajah, W., Saysell, C.G., Wilmot, C.M., Parsons, M.R., Phillips, S.E.V., Knowles, P.F., McPherson, M.J.
Deposit date:2001-08-14
Release date:2001-11-21
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Conserved tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential.
Biochemistry, 40, 2001
1LA1
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GRO-EL FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 188-379
Descriptor:GroEL
Authors:Ashcroft, A.E., Brinker, A., Coyle, J.E., Weber, F., Kaiser, M., Moroder, L., Parsons, M.R., Jager, J., Hartl, U.F., Hayer-Hartl, M., Radford, S.E.
Deposit date:2002-03-27
Release date:2002-04-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural plasticity and noncovalent substrate binding in the GroEL apical domain. A study using electrospay ionization mass spectrometry and fluorescence binding studies.
J.Biol.Chem., 277, 2002
3F1Q
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HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH A LEFLUNOMIDE DERIVATIVE INHIBITOR 1
Descriptor:Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ...
Authors:Heikkila, T., Davies, M., McConkey, G.A., Fishwick, C.W.G., Parsons, M.R., Johnson, A.P.
Deposit date:2008-10-28
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases
J.Med.Chem., 52, 2009
3G0U
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HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH A LEFLUNOMIDE DERIVATIVE INHIBITOR 4
Descriptor:Dihydroorotate dehydrogenase, OROTIC ACID, FLAVIN MONONUCLEOTIDE, ...
Authors:Davis, M., Heikkila, T., McConkey, G.A., Fishwick, C.W.G., Parsons, M.R., Johnson, A.P.
Deposit date:2009-01-28
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases
J.Med.Chem., 52, 2009
3G0X
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HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH A LEFLUNOMIDE DERIVATIVE INHIBITOR 5
Descriptor:Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ...
Authors:Davies, M., Heikkila, T., McConkey, G.A., Fishwick, C.W.G., Parsons, M.R., Johnson, A.P.
Deposit date:2009-01-29
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases
J.Med.Chem., 52, 2009
3LZ2
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STRUCTURE DETERMINATION OF TURKEY EGG WHITE LYSOZYME USING LAUE DIFFRACTION
Descriptor:TURKEY EGG WHITE LYSOZYME
Authors:Howell, P.L., Almo, S.C., Parsons, M.R., Hajdu, J., Petsko, G.A.
Deposit date:1991-09-13
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure determination of turkey egg-white lysozyme using Laue diffraction data.
Acta Crystallogr.,Sect.B, 48, 1992
3ZWS
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STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE WITH A BOUND INHIBITOR
Descriptor:DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL, FLAVIN MONONUCLEOTIDE, ...
Authors:Acklam, P.A., Parsons, M.R.
Deposit date:2011-08-02
Release date:2012-06-27
Last modified:2012-07-11
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Factors Influencing the Specificity of Inhibitor Binding to the Human and Malaria Parasite Dihydroorotate Dehydrogenases.
J.Med.Chem., 55, 2012
3ZWT
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STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE WITH A BOUND INHIBITOR
Descriptor:DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL, FLAVIN MONONUCLEOTIDE, ...
Authors:Acklam, P.A., Parsons, M.R.
Deposit date:2011-08-02
Release date:2012-06-27
Last modified:2012-07-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Factors Influencing the Specificity of Inhibitor Binding to the Human and Malaria Parasite Dihydroorotate Dehydrogenases.
J.Med.Chem., 55, 2012
4S2R
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CRYSTAL STRUCTURE OF X-PROLYL AMINOPEPTIDASE FROM CAENORHABDITIS ELEGANS: A CYTOSOLIC ENZYME WITH A DI-NUCLEAR ACTIVE SITE
Descriptor:Protein APP-1, ZINC ION
Authors:Iyer, S., La-Borde, P., Payne, K.A.P., Parsons, M.R., Turner, A.J., Isaac, R.E., Acharya, K.R.
Deposit date:2015-01-22
Release date:2015-04-22
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (1.949 Å)
Cite:Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site.
FEBS Open Bio, 5, 2015
4S2T
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CRYSTAL STRUCTURE OF X-PROLYL AMINOPEPTIDASE FROM CAENORHABDITIS ELEGANS: A CYTOSOLIC ENZYME WITH A DI-NUCLEAR ACTIVE SITE
Descriptor:Protein APP-1, apstatin, ZINC ION, ...
Authors:Iyer, S., La-Borde, P., Payne, K.A.P., Parsons, M.R., Turner, A.J., Isaac, R.E., Acharya, K.R.
Deposit date:2015-01-22
Release date:2015-04-22
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site.
FEBS Open Bio, 5, 2015
1SPU
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STRUCTURE OF OXIDOREDUCTASE
Descriptor:COPPER AMINE OXIDASE, COPPER (II) ION, CALCIUM ION
Authors:Wilmot, C.M., Phillips, S.E.V.
Deposit date:1996-11-13
Release date:1997-03-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Catalytic mechanism of the quinoenzyme amine oxidase from Escherichia coli: exploring the reductive half-reaction.
Biochemistry, 36, 1997
1D6U
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CRYSTAL STRUCTURE OF E. COLI AMINE OXIDASE ANAEROBICALLY REDUCED WITH BETA-PHENYLETHYLAMINE
Descriptor:COPPER AMINE OXIDASE, COPPER (II) ION, CALCIUM ION, ...
Authors:Wilmot, C.M., Hajdu, J., McPherson, M.J., Knowles, P.F., Phillips, S.E.V.
Deposit date:1999-10-15
Release date:2000-02-02
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Visualization of dioxygen bound to copper during enzyme catalysis.
Science, 286, 1999
1D6Y
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CRYSTAL STRUCTURE OF E. COLI COPPER-CONTAINING AMINE OXIDASE ANAEROBICALLY REDUCED WITH BETA-PHENYLETHYLAMINE AND COMPLEXED WITH NITRIC OXIDE.
Descriptor:COPPER AMINE OXIDASE, COPPER (II) ION, CALCIUM ION, ...
Authors:Wilmot, C.M., Hajdu, J., McPherson, M.J., Knowles, P.F., Phillips, S.E.V.
Deposit date:1999-10-16
Release date:2000-02-02
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Visualization of dioxygen bound to copper during enzyme catalysis.
Science, 286, 1999
1D6Z
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CRYSTAL STRUCTURE OF THE AEROBICALLY FREEZE TRAPPED RATE-DETERMINING CATALYTIC INTERMEDIATE OF E. COLI COPPER-CONTAINING AMINE OXIDASE.
Descriptor:COPPER AMINE OXIDASE, COPPER (II) ION, CALCIUM ION, ...
Authors:Wilmot, C.M., Hajdu, J., McPherson, M.J., Knowles, P.F., Phillips, S.E.V.
Deposit date:1999-10-16
Release date:2000-02-02
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Visualization of dioxygen bound to copper during enzyme catalysis.
Science, 286, 1999
1LVN
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CRYSTAL STRUCTURE OF E. COLI AMINE OXIDASE COMPLEXED WITH TRANYLCYPROMINE
Descriptor:Copper amine oxidase, COPPER (II) ION, CALCIUM ION
Authors:Wilmot, C.M., Phillips, S.E.
Deposit date:2002-05-28
Release date:2003-08-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Medical implications from the crystal structure of a copper-containing amine oxidase complexed with the antidepressant drug tranylcypromine.
Febs Lett., 576, 2004
3FJ6
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HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH A LEFLUNOMIDE DERIVATIVE INHIBITOR 2
Descriptor:Dihydroorotate dehydrogenase, OROTIC ACID, FLAVIN MONONUCLEOTIDE, ...
Authors:Heikkila, T.
Deposit date:2008-12-14
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases
J.Med.Chem., 52, 2009
3FJL
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HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH A LEFLUNOMIDE DERIVATIVE INHIBITOR 3
Descriptor:Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ...
Authors:Heikkila, T.
Deposit date:2008-12-14
Release date:2009-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-based design, synthesis, and characterization of inhibitors of human and Plasmodium falciparum dihydroorotate dehydrogenases
J.Med.Chem., 52, 2009
1D2E
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CRYSTAL STRUCTURE OF MITOCHONDRIAL EF-TU IN COMPLEX WITH GDP
Descriptor:ELONGATION FACTOR TU (EF-TU), MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Andersen, G.R., Thirup, S., Spremulli, L.L., Nyborg, J.
Deposit date:1999-09-23
Release date:1999-09-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:High resolution crystal structure of bovine mitochondrial EF-Tu in complex with GDP.
J.Mol.Biol., 297, 2000
1LS2
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FITTING OF EF-TU AND TRNA IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:Phenylalanine transfer RNA, Elongation Factor Tu
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1LU3
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SEPARATE FITTING OF THE ANTICODON LOOP REGION OF TRNA (NUCLEOTIDE 26-42) IN THE LOW RESOLUTION CRYO-EM MAP OF AN EF-TU TERNARY COMPLEX (GDP AND KIRROMYCIN) BOUND TO E. COLI 70S RIBOSOME
Descriptor:PHENYLALANINE TRANSFER RNA
Authors:Valle, M., Sengupta, J., Swami, N.K., Grassucci, R.A., Burkhardt, N., Nierhaus, K.H., Agrawal, R.K., Frank, J.
Deposit date:2002-05-21
Release date:2002-06-26
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
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