2PNC

Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in Complex with Clonidine

Summary for 2PNC

• Entry DOI: 10.2210/pdb2pnc/pdb
• Related: 1KSI 1OAC 1TU5
• Related PRD ID: PRD_900017
• Descriptor: Copper amine oxidase, liver isozyme, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ... (7 entities in total)
• Functional Keywords: amine oxidase, oxidoreductase, quinoenzyme, tpq, clonidine
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted, extracellular space: Q29437
• Total number of polymer chains: 2
• Total formula weight: 168012.75

Authors

Cendron, L.,Holt, A.,Smith, D.J.,Zanotti, G.,Rigo, A.,Di Paolo, M.L. (deposition date: 2007-04-24, release date: 2008-02-26, Last modification date: 2023-08-30)

• Primary citation: Holt, A.,Smith, D.J.,Cendron, L.,Zanotti, G.,Rigo, A.,Di Paolo, M.L.; Multiple binding sites for substrates and modulators of semicarbazide-sensitive amine oxidases: kinetic consequences; Mol.Pharmacol., 73:525-538, 2008; PubMed: 17989349; DOI: 10.1124/mol.107.040964

Experimental method

X-RAY DIFFRACTION (2.4 Å)