Author results

2ZNO
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A SYNTHETIC AGONIST TIPP703
Descriptor:Peroxisome proliferator-activated receptor gamma, (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid
Authors:Oyama, T., Waku, T., Kasuga, J., Miyachi, H., Morikawa, K.
Deposit date:2008-04-30
Release date:2009-05-05
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Acta Crystallogr.,Sect.D, 65, 2009
2ZNN
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HUMAN PPAR ALPHA LIGAND BINDING DOMAIN IN COMPLEX WITH A SYNTHETIC AGONIST TIPP703
Descriptor:Peroxisome proliferator-activated receptor alpha, (2S)-2-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}benzyl)butanoic acid
Authors:Oyama, T., Toyota, K., Kasuga, J., Miyachi, H., Morikawa, K.
Deposit date:2008-04-30
Release date:2009-05-05
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Acta Crystallogr.,Sect.D, 65, 2009
2ZNP
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HUMAN PPAR DELTA LIGAND BINDING DOMAIN IN COMPLEX WITH A SYNTHETIC AGONIST TIPP204
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, (2S)-2-{4-butoxy-3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]benzyl}butanoic acid
Authors:Oyama, T., Hirakawa, Y., Nagasawa, N., Miyachi, H., Morikawa, K.
Deposit date:2008-04-30
Release date:2009-05-05
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (3 Å)
Cite:Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Acta Crystallogr.,Sect.D, 65, 2009
2ZNQ
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HUMAN PPAR DELTA LIGAND BINDING DOMAIN IN COMPLEX WITH A SYNTHETIC AGONIST TIPP401
Descriptor:Peroxisome proliferator-activated receptor delta, HEPTYL-BETA-D-GLUCOPYRANOSIDE, (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid
Authors:Oyama, T., Hirakawa, Y., Nagasawa, N., Miyachi, H., Morikawa, K.
Deposit date:2008-04-30
Release date:2009-05-05
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures
Acta Crystallogr.,Sect.D, 65, 2009
5BCA
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BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES
Descriptor:PROTEIN (1,4-ALPHA-D-GLUCAN MALTOHYDROLASE.), CALCIUM ION
Authors:Oyama, T., Kusunoki, M., Kishimoto, Y., Takasaki, Y., Nitta, Y.
Deposit date:1999-03-12
Release date:2000-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of beta-amylase from Bacillus cereus var. mycoides at 2.2 A resolution.
J.Biochem.(Tokyo), 125, 1999
1IQP
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CRYSTAL STRUCTURE OF THE CLAMP LOADER SMALL SUBUNIT FROM PYROCOCCUS FURIOSUS
Descriptor:RFCS, ADENOSINE-5'-DIPHOSPHATE
Authors:Oyama, T., Ishino, Y., Cann, I.K.O., Ishino, S., Morikawa, K.
Deposit date:2001-07-24
Release date:2001-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Atomic Structure of the Clamp Loader Small Subunit from Pyrococcus furiosus
Mol.Cell, 8, 2001
1J0Y
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BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH GLUCOSE
Descriptor:Beta-amylase, BETA-D-GLUCOSE, CALCIUM ION
Authors:Oyama, T., Miyake, H., Kusunoki, M., Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
1J0Z
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BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH MALTOSE
Descriptor:Beta-amylase, ALPHA-D-GLUCOSE, BETA-D-GLUCOSE, ...
Authors:Oyama, T., Miyake, H., Kusunoki, M., Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
1J10
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BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH GGX
Descriptor:Beta-amylase, ALPHA-D-GLUCOSE, BETA-D-XYLOPYRANOSE, ...
Authors:Oyama, T., Miyake, H., Kusunoki, M., Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
1J11
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BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH ALPHA-EPG
Descriptor:Beta-amylase, 2-HYDROXYMETHYL-6-OXIRANYLMETHOXY-TETRAHYDRO-PYRAN-3,4,5-TRIOL, CALCIUM ION
Authors:Oyama, T., Miyake, H., Kusunoki, M., Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
1J12
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BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES IN COMPLEX WITH ALPHA-EBG
Descriptor:Beta-amylase, 2-HYDROXYMETHYL-6-(2-OXIRANYL-ETHOXY)-TETRAHYDRO-PYRAN-3,4,5-TRIOL, CALCIUM ION
Authors:Oyama, T., Miyake, H., Kusunoki, M., Nitta, Y.
Deposit date:2002-11-25
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of beta-Amylase from Bacillus cereus var. mycoides in Complexes with Substrate Analogs and Affinity-Labeling Reagents
J.BIOCHEM.(TOKYO), 133, 2003
3ANW
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A PROTEIN COMPLEX ESSENTIAL INITIATION OF DNA REPLICATION
Descriptor:Putative uncharacterized protein
Authors:Oyama, T., Shirai, T., Nagasawa, N., Ishino, Y., Morikawa, K.
Deposit date:2010-09-10
Release date:2011-07-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Architectures of archaeal GINS complexes, essential DNA replication initiation factors
Bmc Biol., 9, 2011
3VSP
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A GAMMA SELECTIVE AGONIST MEKT28
Descriptor:Peroxisome proliferator-activated receptor gamma, (2R)-2-benzyl-3-[3-({[4-(piperidin-1-yl)benzoyl]amino}methyl)-4-propoxyphenyl]propanoic acid
Authors:Oyama, T., Waku, T., Ohashi, M., Morikawa, K., Miyachi, H.
Deposit date:2012-04-30
Release date:2013-05-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28
To be Published
5GHR
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DNA REPLICATION PROTEIN
Descriptor:SsDNA-specific exonuclease, Putative uncharacterized protein, SULFATE ION
Authors:Oyama, T.
Deposit date:2016-06-20
Release date:2016-10-12
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication.
Nucleic Acids Res., 44, 2016
5GHS
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DNA REPLICATION PROTEIN
Descriptor:SsDNA-specific exonuclease, Putative uncharacterized protein, SULFATE ION
Authors:Oyama, T.
Deposit date:2016-06-20
Release date:2016-10-12
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.591 Å)
Cite:Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication.
Nucleic Acids Res., 44, 2016
5GHT
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DNA REPLICATION PROTEIN
Descriptor:SsDNA-specific exonuclease
Authors:Oyama, T.
Deposit date:2016-06-20
Release date:2016-10-12
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication.
Nucleic Acids Res., 44, 2016
2ZJ2
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ARCHAEAL DNA HELICASE HJM APO STATE IN FORM 1
Descriptor:Putative ski2-type helicase, SULFATE ION
Authors:Oyama, T., Oka, H., Fujikane, R., Ishino, Y., Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
2ZJ5
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ARCHAEAL DNA HELICASE HJM COMPLEXED WITH ADP IN FORM 1
Descriptor:Putative ski2-type helicase, SULFATE ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Oyama, T., Oka, H., Fujikane, R., Ishino, Y., Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
2ZJ8
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ARCHAEAL DNA HELICASE HJM APO STATE IN FORM 2
Descriptor:Putative ski2-type helicase
Authors:Oyama, T., Oka, H., Fujikane, R., Ishino, Y., Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
2ZJA
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ARCHAEAL DNA HELICASE HJM COMPLEXED WITH AMPPCP IN FORM 2
Descriptor:Putative ski2-type helicase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Oyama, T., Oka, H., Fujikane, R., Ishino, Y., Morikawa, K.
Deposit date:2008-02-29
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Atomic structures and functional implications of the archaeal RecQ-like helicase Hjm
Bmc Struct.Biol., 9, 2009
3W0K
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CRYSTAL STRUCTURE OF A GLYCOSIDE HYDROLASE
Descriptor:Bifunctional endomannanase/endoglucanase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Oyama, T., Nakamura, H., Morikawa, K., Cann, I.K.O.
Deposit date:2012-10-31
Release date:2013-02-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of a glycoside hydrolase
To be Published
3WMH
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A GAMMMA SELECTIVE SYNTHETIC PARTIAL AGONIST MEKT75
Descriptor:Peroxisome proliferator-activated receptor gamma, N-(phenylsulfonyl)-4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)benzamide
Authors:Oyama, T., Ohashi, M., Miyachi, H., Kusunoki, M.
Deposit date:2013-11-19
Release date:2014-11-19
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Human PPRR gamma ligand binding domain in complex with a gammma selective synthetic partial agonist MEKT75
TO BE PUBLISHED
3VSO
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A GAMMA SELECTIVE AGONIST MEKT21
Descriptor:Peroxisome proliferator-activated receptor gamma, (2R)-2-benzyl-3-[4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)phenyl]propanoic acid
Authors:Oyama, T., Waku, T., Ohashi, M., Morikawa, K., Miyachi, H.
Deposit date:2012-04-30
Release date:2013-05-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and synthesis of a series of alpha-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility
Bioorg.Med.Chem., 21, 2013
3AN3
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A GAMMA SELECTIVE AGONIST MO3S
Descriptor:Peroxisome proliferator-activated receptor gamma, (2S)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid
Authors:Oyama, T., Ohashi, M., Waku, T., Miyachi, H., Morikawa, K.
Deposit date:2010-08-30
Release date:2011-07-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship
J.Med.Chem., 54, 2011
3AN4
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HUMAN PPAR GAMMA LIGAND BINDING DOMAIN IN COMPLEX WITH A GAMMA SELECTIVE AGONIST MO4R
Descriptor:Peroxisome proliferator-activated receptor gamma, (2R)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid
Authors:Oyama, T., Ohashi, M., Waku, T., Miyachi, H., Morikawa, K.
Deposit date:2010-08-30
Release date:2011-07-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship
J.Med.Chem., 54, 2011
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