3VSP

Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28

Summary for 3VSP

Related3an3 3VSO
DescriptorPeroxisome proliferator-activated receptor gamma, (2R)-2-benzyl-3-[3-({[4-(piperidin-1-yl)benzoyl]amino}methyl)-4-propoxyphenyl]propanoic acid (3 entities in total)
Functional Keywordsmainly alpha, nuclear receptor, transcription
Biological sourceHomo sapiens (human)
Cellular locationNucleus P37231
Total number of polymer chains2
Total molecular weight65575.96
Authors
Oyama, T.,Waku, T.,Ohashi, M.,Morikawa, K.,Miyachi, H. (deposition date: 2012-04-30, release date: 2013-05-01, Last modification date: 2017-11-22)
Primary citation
Oyama, T.,Waku, T.,Ohashi, M.,Morikawa, K.,Miyachi, H.
Human PPAR gamma ligand binding domain in complex with a gamma selective agonist mekt28
To be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.274120.6%3.0%3.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3vsp
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Molmil generated image of 3vsp
rotated about x axis by 90°
Molmil generated image of 3vsp
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 3vsp
no rotation
Molmil generated image of 3vsp
rotated about x axis by 90°
Molmil generated image of 3vsp
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3vsp.pdb2.gz [86.96 KB])
Coordinate files for Biological unit (3vsp.pdb1.gz [86.5 KB])