3WMH

Human PPAR gamma ligand binding domain in complex with a gammma selective synthetic partial agonist MEKT75

Summary for 3WMH

• Entry DOI: 10.2210/pdb3wmh/pdb
• Related: 3vso 3vsp
• Descriptor: Peroxisome proliferator-activated receptor gamma, N-(phenylsulfonyl)-4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)benzamide (3 entities in total)
• Functional Keywords: mainly alpha, nuclear receptor, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P37231
• Total number of polymer chains: 2
• Total formula weight: 66122.49

Authors

Oyama, T.,Ohashi, M.,Miyachi, H.,Kusunoki, M. (deposition date: 2013-11-19, release date: 2014-11-19, Last modification date: 2023-11-08)

• Primary citation: Oyama, T.,Ohashi, M.,Miyachi, H.,Kusunoki, M.; Human PPRR gamma ligand binding domain in complex with a gammma selective synthetic partial agonist MEKT75; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.1 Å)