Author results

6OXO
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR2-91
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[{[4-(hydroxymethyl)phenyl]sulfonyl}(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXP
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH UMASS3
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(1S,2R)-1-benzyl-2-hydroxy-3-({[4-(hydroxymethyl)phenyl]sulfonyl}[(2S)-2-methylbutyl]amino)propyl]carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXQ
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH UMASS8
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-1-benzyl-3-[(2-ethylbutyl){[4-(hydroxymethyl)phenyl]sulfonyl}amino]-2-hydroxypropyl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXR
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR-82
分子名称:Protease NL4-3, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[({4-[(1S)-1-hydroxyethyl]phenyl}sulfonyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2.035 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXS
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR-76
分子名称:Protease NL4-3, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-3-hydroxy-4-[({4-[(1R)-1-hydroxyethyl]phenyl}sulfonyl)(2-methylpropyl)amino]-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.989 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXT
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR-84
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{({4-[(1S)-1-hydroxyethyl]phenyl}sulfonyl)[(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.861 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXU
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR-99
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{({4-[(1R)-1-hydroxyethyl]phenyl}sulfonyl)[(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.861 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXV
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR-85
分子名称:Protease NL4-3, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[(2-ethylbutyl)({4-[(1S)-1-hydroxyethyl]phenyl}sulfonyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXW
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR-100
分子名称:Protease NL4-3, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[(2-ethylbutyl)({4-[(1R)-1-hydroxyethyl]phenyl}sulfonyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.982 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXX
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR2-18
分子名称:Protease NL4-3, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1R)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.962 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXY
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR2-19
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1S)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OXZ
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR2-20
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{({4-[(1R)-1,2-dihydroxyethyl]phenyl}sulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.961 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OY0
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR2-21
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{({4-[(1S)-1,2-dihydroxyethyl]phenyl}sulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OY1
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR2-26
分子名称:Protease NL4-3, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1R)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-ethylbutyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OY2
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH LR2-25
分子名称:Protease NL4-3, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1S)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-ethylbutyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, SULFATE ION
著者Lockbaum, G.J., Rusere, L.N., Lee, S.K., Henes, M., Kosovrasti, K., Spielvogel, E., Nalivaika, E.A., Swanstrom, R., KurtYilmaz, N., Schiffer, C.A., Ali, A.
登録日2019-05-14
公開日2019-08-21
最終更新日2019-09-25
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.
J.Med.Chem., 62, 2019
6OPS
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HIV-1 PROTEASE NL4-3 WT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OPT
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HIV-1 PROTEASE NL4-3 V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, SULFATE ION
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OPU
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HIV-1 PROTEASE NL4-3 K45I, M46I, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OPV
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HIV-1 PROTEASE NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OPW
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HIV-1 PROTEASE NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, A71V, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, SULFATE ION, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OPX
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HIV-1 PROTEASE NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, L76V, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OPY
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HIV-1 PROTEASE NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, A71V, L76V, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OPZ
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HIV-1 PROTEASE NL4-3 I13V, G16E, V32I, L33F, K45I, M46I, I54L, A71V, L76V, V82F, I84V MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:Protease NL4-3, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Lockbaum, G.J., Henes, M., Kosovrasti, K., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A.
登録日2019-04-25
公開日2019-09-04
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Acs Chem.Biol., 2019
6OOS
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HIV-1 PROTEASE NL4-3 L90M MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:NL4-3 PROTEASE, SULFATE ION, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Henes, M., Kosovrasti, K., Lockbaum, G.J., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A., Whitfield, T.W.
登録日2019-04-23
公開日2019-08-21
最終更新日2019-09-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance.
Biochemistry, 58, 2019
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HIV-1 PROTEASE NL4-3 L89V, L90M MUTANT IN COMPLEX WITH DARUNAVIR
分子名称:NL4-3 PROTEASE, SULFATE ION, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
著者Henes, M., Kosovrasti, K., Lockbaum, G.J., Leidner, F., Nachum, G.S., Nalivaika, E.A., Bolon, D.N.A., KurtYilmaz, N., Schiffer, C.A., Whitfield, T.W.
登録日2019-04-23
公開日2019-08-21
最終更新日2019-09-11
実験手法X-RAY DIFFRACTION (1.822 Å)
主引用文献Molecular Determinants of Epistasis in HIV-1 Protease: Elucidating the Interdependence of L89V and L90M Mutations in Resistance.
Biochemistry, 58, 2019