6W6T

WT HIV-1 Protease in Complex with Phosphonated UMass6 (PU6)

Summary for 6W6T

• Entry DOI: 10.2210/pdb6w6t/pdb
• Descriptor: Protease, SULFATE ION, diethyl [(4-{(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-ethylbutyl)amino}-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxybutyl}phenoxy)methyl]phosphonate, ... (4 entities in total)
• Functional Keywords: hiv, protease, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 2
• Total formula weight: 22693.68

Authors

Lockbaum, G.J.,Henes, M.,Kosovrasti, K.,Nalivaika, E.A.,Ali, A.,KurtYilmaz, N.,Schiffer, C.A. (deposition date: 2020-03-17, release date: 2021-03-17, Last modification date: 2023-10-18)

• Primary citation: Lockbaum, G.J.,Henes, M.,Kosovrasti, K.,Nalivaika, E.A.,Ali, A.,KurtYilmaz, N.,Schiffer, C.A.; To Be Determined; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.84 Å)