6W6Q

WT HTLV-1 Protease in Complex with Darunavir (DRV)

Summary for 6W6Q

• Entry DOI: 10.2210/pdb6w6q/pdb
• Descriptor: HTLV-1 Protease, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE (3 entities in total)
• Functional Keywords: htlv, protease, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human T-cell leukemia virus type I
• Total number of polymer chains: 2
• Total formula weight: 25680.82

Authors

Lockbaum, G.J.,Henes, M.,Kosovrasti, K.,Nalivaika, E.A.,Ali, A.,KurtYilmaz, N.,Schiffer, C.A. (deposition date: 2020-03-17, release date: 2021-03-17, Last modification date: 2023-10-18)

• Primary citation: Lockbaum, G.J.,Henes, M.,Kosovrasti, K.,Nalivaika, E.A.,Ali, A.,KurtYilmaz, N.,Schiffer, C.A.; To Be Determined; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)