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6W6Q

WT HTLV-1 Protease in Complex with Darunavir (DRV)

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
B0004190molecular_functionaspartic-type endopeptidase activity
B0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues20
Detailsbinding site for residue 017 B 201
ChainResidue
AASP32
BGLY34
BALA35
BASP36
BMET37
BVAL56
BLEU57
BGLY58
BALA59
BLEU91
BTRP98
AGLY34
BILE100
AASP36
AMET37
ALEU57
AGLY58
AALA59
ATRP98
BASP32

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADMTVI
ChainResidueDetails
BALA29-ILE40

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: For protease activity; shared with dimeric partner => ECO:0000255|PROSITE-ProRule:PRU00275
ChainResidueDetails
BASP32
AASP32

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PDB entries from 2024-10-30

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