6W6Q
WT HTLV-1 Protease in Complex with Darunavir (DRV)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | HTLV-1 Protease | polymer | 116 | 12566.6 | 2 | UniProt (A0A1Y1C9N2) Pfam (PF00077) UniProt (by SIFTS) (P10274) | Human T-cell leukemia virus type I | |
| 2 | C (B) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) | |||
| 3 | D, E (B, A) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 116 (UniProt: A0A1Y1C9N2)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 66 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 547.7 | |
| All* | Total formula weight | 25680.8 |
