6W6Q
WT HTLV-1 Protease in Complex with Darunavir (DRV)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | HTLV-1 Protease | polymer | 116 | 12566.6 | 2 | UniProt (A0A1Y1C9N2) Pfam (PF00077) UniProt (by SIFTS) (P10274) | Human T-cell leukemia virus type I | |
| 2 | C (B) | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE | non-polymer | 547.7 | 1 | Chemie (017) PubChem (213039) PubChem (23545473) PubChem (44400512) PubChem (44578485) PubChem (52949690) PubChem (58330571) PubChem (60170302) PubChem (70329566) PubChem (66725685) PubChem (3001874) PubChem (6320436) PubChem (6320437) PubChem (89334570) PubChem (89394603) PubChem (102206609) PubChem (6320435) PubChem (101897907) PubChem (125136514) PubChem (102206607) PubChem (102206608) PubChem (118243427) PubChem (118243428) PubChem (118243429) PubChem (125136515) PubChem (129010372) PubChem (131632443) PubChem (131667685) PubChem (134694394) PubChem (137704505) PubChem (137704865) PubChem (138631483) PubChem (138631484) PubChem (138631622) PubChem (144227995) PubChem (145507139) PubChem (147231834) PubChem (156183881) PubChem (156183911) PubChem (171370671) | |||
| 3 | D, E (B, A) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 116 (UniProt: A0A1Y1C9N2)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 66 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 547.7 | |
| All* | Total formula weight | 25680.8 |
