1J8M | | SIGNAL RECOGNITION PARTICLE CONSERVED GTPASE DOMAIN FROM A. AMBIVALENS | | Descriptor: | SIGNAL RECOGNITION 54 KDA PROTEIN | | Authors: | Montoya, G., te Kaat, K., Moll, R., Schafer, G., Sinning, I. | | Deposit date: | 2001-05-22 | | Release date: | 2001-06-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of the conserved GTPase of SRP54 from the archaeon Acidianus ambivalens and its comparison with related structures suggests a model for the SRP-SRP receptor complex.
Structure Fold.Des., 8, 2000
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1J8Y | | SIGNAL RECOGNITION PARTICLE CONSERVED GTPASE DOMAIN FROM A. AMBIVALENS T112A MUTANT | | Descriptor: | SIGNAL RECOGNITION 54 KDA PROTEIN | | Authors: | Montoya, G., te Kaat, K., Moll, R., Schaerfer, G., Sinning, I. | | Deposit date: | 2001-05-23 | | Release date: | 2001-06-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure of the conserved GTPase of SRP54 from the archaeon Acidianus ambivalens and its comparison with related structures suggests a model for the SRP-SRP receptor complex.
Structure Fold.Des., 8, 2000
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1FTS | |
4ZTD | | CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH A TRAIP PEPTIDE | | Descriptor: | Proliferating cell nuclear antigen, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, ALA-GLY-ALA-GLY-ALA | | Authors: | Montoya, G., Mortuza, G.B., Blanco, F.J., Ibanez de Opakua, A. | | Deposit date: | 2015-05-14 | | Release date: | 2015-12-16 | | Last modified: | 2016-01-13 | | Method: | X-RAY DIFFRACTION (2.199 Å) | | Cite: | TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
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5MGA | |
6GTD | | TRANSIENT STATE STRUCTURE OF CRISPR-CPF1 (CAS12A) I2 CONFORMATION | | Descriptor: | CRISPR-associated endonuclease Cas12a, RNA (28-MER), DNA (5'-D(P*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ... | | Authors: | Montoya, G., Mesa, P. | | Deposit date: | 2018-06-18 | | Release date: | 2018-12-19 | | Last modified: | 2018-12-26 | | Method: | ELECTRON MICROSCOPY (4.24 Å) | | Cite: | Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
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6GTE | | TRANSIENT STATE STRUCTURE OF CRISPR-CPF1 (CAS12A) I3 CONFORMATION | | Descriptor: | CRISPR-associated endonuclease Cas12a, RNA (29-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ... | | Authors: | Montoya, G., Mesa, P., Stella, S. | | Deposit date: | 2018-06-18 | | Release date: | 2018-12-19 | | Last modified: | 2018-12-26 | | Method: | ELECTRON MICROSCOPY (4.07 Å) | | Cite: | Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
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6GTF | | TRANSIENT STATE STRUCTURE OF CRISPR-CPF1 (CAS12A) I5 CONFORMATION | | Descriptor: | CRISPR-associated endonuclease Cas12a, RNA (29-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), ... | | Authors: | Montoya, G., Mesa, P., Stella, S. | | Deposit date: | 2018-06-18 | | Release date: | 2018-12-19 | | Last modified: | 2018-12-26 | | Method: | ELECTRON MICROSCOPY (3.63 Å) | | Cite: | Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity.
Cell, 175, 2018
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2OGQ | | MOLECULAR AND STRUCTURAL BASIS OF PLK1 SUBSTRATE RECOGNITION: IMPLICATIONS IN CENTROSOMAL LOCALIZATION | | Descriptor: | Serine/threonine-protein kinase PLK1 | | Authors: | Garcia-Alvarez, B., de Carcer, G., Ibanez, S., Bragado-Nilsson, E., Montoya, G. | | Deposit date: | 2007-01-08 | | Release date: | 2007-02-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2OJX | | MOLECULAR AND STRUCTURAL BASIS OF POLO-LIKE KINASE 1 SUBSTRATE RECOGNITION: IMPLICATIONS IN CENTROSOMAL LOCALIZATION | | Descriptor: | Serine/threonine-protein kinase PLK1, Synthetic peptide | | Authors: | Garcia-Alvarez, B., de Carcer, G., Ibanez, S., Bragado-Nilsson, E., Montoya, G. | | Deposit date: | 2007-01-15 | | Release date: | 2007-02-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2VTX | | ACTIVATION OF NUCLEOPLASMIN, AN OLIGOMERIC HISTONE CHAPERONE, CHALLENGES ITS STABILITY | | Descriptor: | NPM-A PROTEIN | | Authors: | Taneva, S.G., Munoz, I.G., Franco, G., Falces, J., Arregi, I., Muga, A., Montoya, G., Urbaneja, M.A., Banuelos, S. | | Deposit date: | 2008-05-16 | | Release date: | 2008-12-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Activation of Nucleoplasmin, an Oligomeric Histone Chaperone, Challenges its Stability.
Biochemistry, 47, 2008
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3BZI | | MOLECULAR AND STRUCTURAL BASIS OF POLO-LIKE KINASE 1 SUBSTRATE RECOGNITION: IMPLICATIONS IN CENTROSOMAL LOCALIZATION | | Descriptor: | Serine/threonine-protein kinase PLK1, 9 mer peptide from M-phase inducer phosphatase 3, FORMIC ACID | | Authors: | Garcia-Alvarez, B., de Carcer, G., Ibanez, S., Bragado-Nilsson, E., Montoya, G. | | Deposit date: | 2008-01-18 | | Release date: | 2008-02-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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5JNO | |
2XSM | | CRYSTAL STRUCTURE OF THE MAMMALIAN CYTOSOLIC CHAPERONIN CCT IN COMPLEX WITH TUBULIN | | Descriptor: | CCT | | Authors: | Munoz, I.G., Yebenes, H., Zhou, M., Mesa, P., Serna, M., Bragado-Nilsson, E., Beloso, A., Robinson, C.V., Valpuesta, J.M., Montoya, G. | | Deposit date: | 2010-10-29 | | Release date: | 2010-12-15 | | Method: | X-RAY DIFFRACTION (5.5 Å) | | Cite: | Crystal Structure of the Open Conformation of the Mammalian Chaperonin Cct in Complex with Tubulin.
Nat.Struct.Mol.Biol., 18, 2011
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4A7C | | CRYSTAL STRUCTURE OF PIM1 KINASE WITH ETP46546 | | Descriptor: | PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE PIM-1, N-(piperidin-4-ylmethyl)-3-[3-(trifluoromethyloxy)phenyl]-[1,2,3]triazolo[4,5-b]pyridin-5-amine, IMIDAZOLE, ... | | Authors: | Mazzorana, M., Montoya, G. | | Deposit date: | 2011-11-12 | | Release date: | 2012-02-15 | | Last modified: | 2015-01-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Hit to Lead Evaluation of 1,2,3-Triazolo[4,5-B]Pyridines as Pim Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
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4D2G | | CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH P15 PEPTIDE | | Descriptor: | PROLIFERATING CELL NUCLEAR ANTIGEN, P15 | | Authors: | DeBiasio, A., Ibanez, A., Mortuza, G., Molina, R., Cordeiro, T.N., Castillo, F., Villate, M., Merino, N., Lelli, M., Diercks, T., Luque, I., Bernardo, P., Montoya, G., Blanco, F.J. | | Deposit date: | 2014-05-09 | | Release date: | 2015-03-18 | | Last modified: | 2015-03-25 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structure of P15(Paf)-PCNA Complex and Implications for Clamp Sliding During DNA Replication and Repair.
Nat.Commun., 6, 2015
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1QZW | | CRYSTAL STRUCTURE OF THE COMPLETE CORE OF ARCHAEAL SRP AND IMPLICATIONS FOR INTER-DOMAIN COMMUNICATION | | Descriptor: | 7S RNA, Signal recognition 54 kDa protein | | Authors: | Rosendal, K.R., Wild, K., Montoya, G., Sinning, I. | | Deposit date: | 2003-09-18 | | Release date: | 2003-11-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Crystal structure of the complete core of archaeal signal recognition particle and implications for interdomain communication
Proc.Natl.Acad.Sci.USA, 100, 2003
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1QZX | |
1UNF | | THE CRYSTAL STRUCTURE OF THE EUKARYOTIC FESOD FROM VIGNA UNGUICULATA SUGGESTS A NEW ENZYMATIC MECHANISM | | Descriptor: | IRON SUPEROXIDE DISMUTASE, FE (III) ION | | Authors: | Munoz, I.G., Moran, J.F., Becana, M., Montoya, G. | | Deposit date: | 2003-09-10 | | Release date: | 2004-10-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | The Crystal Structure of an Eukaryotic Iron Superoxide Dismutase Suggests Intersubunit Cooperation During Catalysis
Protein Sci., 14, 2005
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2JA4 | | CRYSTAL STRUCTURE OF CD5 DOMAIN III REVEALS THE FOLD OF A GROUP B SCAVENGER CYSTEINE-RICH RECEPTOR | | Descriptor: | T-CELL SURFACE GLYCOPROTEIN CD5 | | Authors: | Rodamilans, B., Munoz, I.G., Sarrias, M.R., Lozano, F., Blanco, F.J., Montoya, G. | | Deposit date: | 2006-11-21 | | Release date: | 2007-03-06 | | Last modified: | 2017-06-28 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Crystal Structure of the Third Extracellular Domain of Cd5 Reveals the Fold of a Group B Scavenger Cysteine-Rich Receptor Domain.
J.Biol.Chem., 282, 2007
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2JGN | | DDX3 HELICASE DOMAIN | | Descriptor: | ATP-DEPENDENT RNA HELICASE DDX3X | | Authors: | Rodamilans, B., Montoya, G. | | Deposit date: | 2007-02-13 | | Release date: | 2008-05-13 | | Last modified: | 2012-05-30 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Expression, Purification, Crystallization and Preliminary X-Ray Diffraction Analysis of the Ddx3 RNA Helicase Domain.
Acta Crystallogr.,Sect.F, 63, 2007
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2O7M | | THE C-TERMINAL LOOP OF THE HOMING ENDONUCLEASE I-CREI IS ESSENTIAL FOR DNA BINDING AND CLEAVAGE. IDENTIFICATION OF A NOVEL SITE FOR SPECIFICITY ENGINEERING IN THE I-CREI SCAFFOLD | | Descriptor: | DNA endonuclease I-CreI | | Authors: | Prieto, J., Redondo, P., Padro, D., Blanco, F.J., Paques, F., Montoya, G. | | Deposit date: | 2006-12-11 | | Release date: | 2007-10-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage
Nucleic Acids Res., 35, 2007
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2VBJ | | MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS | | Descriptor: | DNA ENDONUCLEASE I-CREI, 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP*AP*GP*GP*AP*TP*CP*CP*TP*AP*A)-3', 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP*AP*AP*AP*AP*GP*GP*CP*AP*GP*A)-3', ... | | Authors: | Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Arnould, S., Perez, C., Cabaniols, J.P., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G. | | Deposit date: | 2007-09-14 | | Release date: | 2008-10-28 | | Last modified: | 2019-05-29 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
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2VBL | | MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS | | Descriptor: | DNA ENDONUCLEASE I-CREI, 5'-D(*DT*DC*DT*DG*DC*DC*DT*DT*DT*DT*DT*DT *DGP*DAP)-3', 5'-D(*DT*DT*DA*DG*DG*DA*DT*DC*DC*DT*DT*DC *DAP*DAP)-3', ... | | Authors: | Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Arnould, S., Perez, C., Cabaniols, J.P., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G. | | Deposit date: | 2007-09-14 | | Release date: | 2008-10-28 | | Last modified: | 2012-06-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
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2VBN | | MOLECULAR BASIS OF HUMAN XPC GENE RECOGNITION AND CLEAVAGE BY ENGINEERED HOMING ENDONUCLEASE HETERODIMERS | | Descriptor: | DNA ENDONUCLEASE I-CREI, 5'-D(*TP*TP*AP*GP*GP*AP*TP*CP*CP*TP *TP*CP*AP*AP)-3', 5'-D(*TP*CP*TP*GP*CP*CP*TP*TP*TP*TP *TP*TP*GP*AP)-3', ... | | Authors: | Redondo, P., Prieto, J., Munoz, I.G., Alibes, A., Stricher, F., Serrano, L., Arnould, S., Perez, C., Cabaniols, J.P., Duchateau, P., Paques, F., Blanco, F.J., Montoya, G. | | Deposit date: | 2007-09-14 | | Release date: | 2008-10-28 | | Last modified: | 2012-06-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
Nature, 456, 2008
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