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6G19
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 74-DEGREE HELICAL TWIST
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), RNA (5'-R(P*CP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-03-20
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1S
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 87-DEGREE HELICAL TWIST
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-03-21
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6G1X
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 91-DEGREE HELICAL TWIST
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-03-22
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GJZ
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT IN COMPLEX WITH AMPPNP
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), RNA (5'-R(P*CP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-05-17
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKH
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT IN COMPLEX WITH ADP-ALF4
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*GP*UP*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*A)-3'), RNA (5'-R(P*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*GP*AP*C)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-05-21
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6GKM
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT IN COMPLEX WITH ATP (10 MM)
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*CP*AP*AP*GP*CP*CP*GP*AP*GP*GP*AP*GP*AP*G)-3'), RNA (5'-R(P*CP*UP*CP*UP*CP*CP*UP*CP*GP*GP*CP*UP*UP*G)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-05-21
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H61
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 89 DEGREE TWIST AND WITHOUT NUCLEOTIDE
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-07-25
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
6H66
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CRYOEM STRUCTURE OF THE MDA5-DSRNA FILAMENT WITH 93 DEGREE TWIST AND WITHOUT NUCLEOTIDE
分子名称:Interferon-induced helicase C domain-containing protein 1, RNA (5'-R(P*UP*CP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*AP*CP*G)-3'), RNA (5'-R(P*CP*GP*UP*CP*AP*UP*GP*CP*GP*CP*AP*UP*GP*GP*A)-3'), ...
著者Yu, Q., Qu, K., Modis, Y.
登録日2018-07-26
公開日2018-11-21
最終更新日2019-01-02
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis.
Mol. Cell, 72, 2018
5OF9
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CRYSTAL STRUCTURE OF HUMAN MORC2 (RESIDUES 1-603)
分子名称:MORC family CW-type zinc finger protein 2, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Douse, C.H., Shamin, M., Modis, Y.
登録日2017-07-10
公開日2018-02-14
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.807 Å)
主引用文献Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
5OFA
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CRYSTAL STRUCTURE OF HUMAN MORC2 (RESIDUES 1-603) WITH SPINAL MUSCULAR ATROPHY MUTATION T424R
分子名称:MORC family CW-type zinc finger protein 2, ZINC ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Douse, C.H., Liu, Y., Modis, Y.
登録日2017-07-10
公開日2018-02-14
最終更新日2018-08-08
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
5OFB
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CRYSTAL STRUCTURE OF HUMAN MORC2 (RESIDUES 1-603) WITH SPINAL MUSCULAR ATROPHY MUTATION S87L
分子名称:MORC family CW-type zinc finger protein 2, ZINC ION, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Douse, C.H., Liu, Y., Modis, Y.
登録日2017-07-10
公開日2018-02-14
最終更新日2018-08-08
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms.
Nat Commun, 9, 2018
5VSL
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CRYSTAL STRUCTURE OF VIPERIN WITH BOUND [4FE-4S] CLUSTER AND S-ADENOSYLHOMOCYSTEINE (SAH)
分子名称:Radical S-adenosyl methionine domain-containing protein 2, IRON/SULFUR CLUSTER, S-ADENOSYL-L-HOMOCYSTEINE
著者Fenwick, M.K., Li, Y., Cresswell, P., Modis, Y., Ealick, S.E.
登録日2017-05-11
公開日2017-06-14
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.972 Å)
主引用文献Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VSM
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CRYSTAL STRUCTURE OF VIPERIN WITH BOUND [4FE-4S] CLUSTER, 5'-DEOXYADENOSINE, AND L-METHIONINE
分子名称:Radical S-adenosyl methionine domain-containing protein 2, IRON/SULFUR CLUSTER, 5'-DEOXYADENOSINE, ...
著者Fenwick, M.K., Li, Y., Cresswell, P., Modis, Y., Ealick, S.E.
登録日2017-05-11
公開日2017-06-14
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural studies of viperin, an antiviral radical SAM enzyme.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5J81
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CRYSTAL STRUCTURE OF GLYCOPROTEIN C FROM PUUMALA VIRUS IN THE POST-FUSION CONFORMATION (PH 6.0)
分子名称:Envelopment polyprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Willensky, S., Dessau, M.
登録日2016-04-07
公開日2016-10-05
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.
Plos Pathog., 12, 2016
5J9H
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CRYSTAL STRUCTURE OF GLYCOPROTEIN C FROM PUUMALA VIRUS IN THE POST-FUSION CONFORMATION (PH 8.0)
分子名称:Envelopment polyprotein, SULFATE ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Willensky, S., Dessau, M.
登録日2016-04-10
公開日2016-10-05
最終更新日2016-11-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.
Plos Pathog., 12, 2016
5ELX
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S. CEREVISIAE DBP5 BOUND TO RNA AND MANT-ADP BEF3
分子名称:ATP-dependent RNA helicase DBP5, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), [(2~{R},3~{R},4~{R},5~{S})-2-(6-aminopurin-9-yl)-4-oxidanyl-5-[[oxidanyl(phosphonooxy)phosphoryl]oxymethyl]oxolan-3-yl] 2-(methylamino)benzoate, ...
著者Merchant, M.K., Modis, Y.
登録日2015-11-05
公開日2016-02-24
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Pi Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5).
J.Mol.Biol., 428, 2016
4KW6
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CRYSTAL STRUCTURE OF PEROXIREDOXIN-1 (C-TERMINAL TRUNCATION MUTANT) FROM THE HUMAN HOOKWORM ANCYLOSTOMA CEYLANICUM BOUND TO CONOIDIN A
分子名称:Peroxiredoxin-1, 2,3-bis(bromomethyl)quinoxaline 1,4-dioxide
著者Nguyen, J.B., Modis, Y.
登録日2013-05-23
公開日2013-07-31
最終更新日2013-09-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A.
Chem.Biol., 20, 2013
4FH8
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CRYSTAL STRUCTURE OF PEROXIREDOXIN-1 FROM THE HUMAN HOOKWORM ANCYLOSTOMA CEYLANICUM
分子名称:AcePrx-1
著者Nguyen, J.B., Modis, Y.
登録日2012-06-05
公開日2013-06-12
最終更新日2013-09-11
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A.
Chem.Biol., 20, 2013
4JNT
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CRYSTAL STRUCTURE OF THE ECTODOMAIN OF BOVINE VIRAL DIARRHEA VIRUS 1 E2 ENVELOPE PROTEIN
分子名称:Envelope glycoprotein E2, N-ACETYL-D-GLUCOSAMINE
著者Li, Y., Wang, J., Modis, Y.
登録日2013-03-15
公開日2013-04-17
最終更新日2013-05-22
実験手法X-RAY DIFFRACTION (4.09 Å)
主引用文献Crystal structure of glycoprotein E2 from bovine viral diarrhea virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4ILD
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CRYSTAL STRUCTURE OF TRUNCATED BOVINE VIRAL DIARRHEA VIRUS 1 E2 ENVELOPE PROTEIN
分子名称:Envelope glycoprotein E2, N-ACETYL-D-GLUCOSAMINE, CALCIUM ION, ...
著者Modis, Y., Li, Y., Wang, J.
登録日2012-12-30
公開日2013-04-10
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Crystal structure of glycoprotein E2 from bovine viral diarrhea virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4DT5
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CRYSTAL STRUCTURE OF RHAGIUM INQUISITOR ANTIFREEZE PROTEIN
分子名称:Antifreeze protein, SULFATE ION, GLYCEROL
著者Meng, W., Nguyen, J.B., Hakim, A., Thakral, D., Zhu, D.F.
登録日2012-02-20
公開日2013-03-13
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of an insect antifreeze protein and its implications for ice binding.
J.Biol.Chem., 288, 2013
4HJ1
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CRYSTAL STRUCTURE OF GLYCOPROTEIN C FROM RIFT VALLEY FEVER VIRUS (GLYCOSYLATED)
分子名称:ENVELOPE GLYCOPROTEIN, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
著者Dessau, M., Modis, Y.
登録日2012-10-12
公開日2013-01-16
最終更新日2013-02-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of glycoprotein C from Rift Valley fever virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4HJC
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CRYSTAL STRUCTURE OF GLYCOPROTEIN C FROM RIFT VALLEY FEVER VIRUS (NON-GLYCOSYLATED)
分子名称:ENVELOPE GLYCOPROTEIN
著者Dessau, M., Modis, Y.
登録日2012-10-12
公開日2013-01-16
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Crystal structure of glycoprotein C from Rift Valley fever virus.
Proc.Natl.Acad.Sci.USA, 110, 2013
4DQ5
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STRUCTURAL INVESTIGATION OF BACTERIOPHAGE PHI6 LYSIN (WT)
分子名称:Membrane protein Phi6 P5wt, 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
著者Dessau, M.A., Modis, Y.
登録日2012-02-15
公開日2013-01-02
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.395 Å)
主引用文献Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
4DQ7
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STRUCTURAL INVESTIGATION OF BACTERIOPHAGE PHI6 LYSIN (V207F MUTANT)
分子名称:Membrane protein Phi6 P5
著者Dessau, M.A., Modis, Y.
登録日2012-02-15
公開日2013-01-02
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme.
PLoS Genet, 8, 2012
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