6IEM | | ARGININOSUCCINATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | Argininosuccinate lyase, GLYCEROL, 1,2-ETHANEDIOL, ... | | Authors: | Paul, A., Mishra, A., Surolia, A., Vijayan, M. | | Deposit date: | 2018-09-14 | | Release date: | 2019-02-20 | | Last modified: | 2019-04-17 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism.
IUBMB Life, 71, 2019
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6IEN | | SUBSTRATE/PRODUCT BOUND ARGININOSUCCINATE LYASE FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | Argininosuccinate lyase, ARGININOSUCCINATE, FUMARIC ACID, ... | | Authors: | Paul, A., Mishra, A., Surolia, A., Vijayan, M. | | Deposit date: | 2018-09-14 | | Release date: | 2019-02-20 | | Last modified: | 2019-04-17 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies on M. tuberculosis argininosuccinate lyase and its liganded complex: Insights into catalytic mechanism.
IUBMB Life, 71, 2019
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4LQ6 | | CRYSTAL STRUCTURE OF RV3717 REVEALS A NOVEL AMIDASE FROM M. TUBERCULOSIS | | Descriptor: | N-acetymuramyl-L-alanine amidase-related protein, ZINC ION, SULFATE ION, ... | | Authors: | Kumar, A., Kumar, S., Kumar, D., Mishra, A., Dewangan, R.P., Shrivastava, P., Ramachandran, S., Taneja, B. | | Deposit date: | 2013-07-17 | | Release date: | 2013-12-04 | | Last modified: | 2014-01-15 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | The structure of Rv3717 reveals a novel amidase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 69, 2013
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2HV8 | | CRYSTAL STRUCTURE OF GTP-BOUND RAB11 IN COMPLEX WITH FIP3 | | Descriptor: | Ras-related protein Rab-11A, Rab11 family-interacting protein 3, MAGNESIUM ION, ... | | Authors: | Eathiraj, S., Mishra, A., Prekeris, R., Lambright, D.G. | | Deposit date: | 2006-07-27 | | Release date: | 2006-11-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes.
J.Mol.Biol., 364, 2006
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3MJH | | CRYSTAL STRUCTURE OF HUMAN RAB5A IN COMPLEX WITH THE C2H2 ZINC FINGER OF EEA1 | | Descriptor: | Ras-related protein Rab-5A, Early endosome antigen 1, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Mishra, A.K., Eathiraj, S., Lambright, D.G. | | Deposit date: | 2010-04-12 | | Release date: | 2010-05-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1).
Proc.Natl.Acad.Sci.USA, 107, 2010
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3QDH | |
3SNY | |
3SNZ | |
3SO0 | |
3SO1 | |
5XI1 | | STRUCTURAL INSIGHT OF FLAVONOIDS BINDING TO CAG REPEAT RNA THAT CAUSES HUNTINGTON'S DISEASE (HD) AND SPINOCEREBELLAR ATAXIA (SCAS) | | Descriptor: | RNA (5'-R(P*CP*CP*GP*CP*AP*GP*CP*GP*G)-3'), 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE | | Authors: | Tawani, A., Mishra, S.K., Khan, E., Kumar, A. | | Deposit date: | 2017-04-25 | | Release date: | 2018-08-08 | | Method: | SOLUTION NMR | | Cite: | Myricetin Reduces Toxic Level of CAG Repeats RNA in Huntington's Disease (HD) and Spino Cerebellar Ataxia (SCAs).
ACS Chem. Biol., 13, 2018
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6HHO | | CRYSTAL STRUCTURE OF RIP1 KINASE IN COMPLEX WITH GSK547 | | Descriptor: | Receptor-interacting serine/threonine-protein kinase 1, 6-[4-[(5~{S})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile | | Authors: | Thorpe, J.H., Harris, P.A. | | Deposit date: | 2018-08-28 | | Release date: | 2018-12-12 | | Method: | X-RAY DIFFRACTION (3.49 Å) | | Cite: | RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Cancer Cell, 34, 2018
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2WD5 | | SMC HINGE HETERODIMER (MOUSE) | | Descriptor: | STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A, STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 | | Authors: | Michie, K.A., Haering, C.H., Nasmyth, K., Lowe, J. | | Deposit date: | 2009-03-20 | | Release date: | 2010-08-11 | | Last modified: | 2012-10-10 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A Positively Charged Channel within the Smc1/Smc3 Hinge Required for Sister Chromatid Cohesion.
Embo J., 30, 2011
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3TVY | |
3TW0 | |
3TXA | | STRUCTURAL ANALYSIS OF ADHESIVE TIP PILIN, GBS104 FROM GROUP B STREPTOCOCCUS AGALACTIAE | | Descriptor: | Cell wall surface anchor family protein, MAGNESIUM ION, CADMIUM ION, ... | | Authors: | Krishnan, V., Narayana, S.V.L. | | Deposit date: | 2011-09-23 | | Release date: | 2013-03-27 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (2.619 Å) | | Cite: | Structure of Streptococcus agalactiae tip pilin GBS104: a model for GBS pili assembly and host interactions.
Acta Crystallogr.,Sect.D, 69, 2013
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4K4E | | CO-CRYSTAL STRUCTURE OF TNKS1 WITH COMPOUND 52 [N~2-(5-CHLORO-2-METHOXYPHENYL)-N-[TRANS-4-(2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL)CYCLOHEXYL]GLYCINAMIDE] | | Descriptor: | Tankyrase-1, ZINC ION, N~2~-(5-chloro-2-methoxyphenyl)-N-[trans-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)cyclohexyl]glycinamide | | Authors: | Huang, X. | | Deposit date: | 2013-04-12 | | Release date: | 2013-06-05 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
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4K4F | | CO-CRYSTAL STRUCTURE OF TNKS1 WITH COMPOUND 18 [4-[(4S)-5,5-DIMETHYL-2-OXO-4-PHENYL-1,3-OXAZOLIDIN-3-YL]-N-(QUINOLIN-8-YL)BENZAMIDE] | | Descriptor: | Tankyrase-1, ZINC ION, 4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-N-(quinolin-8-yl)benzamide | | Authors: | Huang, X., Bregman, H., Wilson, C., DiMauro, E., Gunaydin, H. | | Deposit date: | 2013-04-12 | | Release date: | 2013-06-05 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
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4MSG | | CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 22 | | Descriptor: | Tankyrase-1, ZINC ION, 3-[(4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]-N-[trans-4-(5-phenyl-1,3,4-oxadiazol-2-yl)cyclohexyl]propanamide | | Authors: | Huang, X. | | Deposit date: | 2013-09-18 | | Release date: | 2013-12-25 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
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4MSK | | CO-CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 34 | | Descriptor: | Tankyrase-1, ZINC ION, 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]propanamide | | Authors: | Huang, X. | | Deposit date: | 2013-09-18 | | Release date: | 2013-12-25 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
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4MT9 | | CO-CRYSTAL STRUCTURE OF TANKYRASE 1 WITH COMPOUND 49 | | Descriptor: | Tankyrase-1, ZINC ION, N-[trans-4-(4-cyanophenoxy)cyclohexyl]-3-[(4-oxo-3,4-dihydroquinazolin-2-yl)sulfanyl]propanamide | | Authors: | Huang, X. | | Deposit date: | 2013-09-19 | | Release date: | 2013-12-25 | | Last modified: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
J.Med.Chem., 56, 2013
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3ENT | |
3ENU | |
3HZ2 | |
3HZB | |
