Author results

5DAT
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING EIF5A
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-20
Release date:2016-08-31
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
1YKQ
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CRYSTAL STRUCTURE OF DIELS-ALDER RIBOZYME
Descriptor:Diels-Alder ribozyme, CADMIUM ION, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YKV
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CRYSTAL STRUCTURE OF THE DIELS-ALDER RIBOZYME COMPLEXED WITH THE PRODUCT OF THE REACTION BETWEEN N-PENTYLMALEIMIDE AND COVALENTLY ATTACHED 9-HYDROXYMETHYLANTHRACENE
Descriptor:Diels-Alder ribozyme, (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YLS
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CRYSTAL STRUCTURE OF SELENIUM-MODIFIED DIELS-ALDER RIBOZYME COMPLEXED WITH THE PRODUCT OF THE REACTION BETWEEN N-PENTYLMALEIMIDE AND COVALENTLY ATTACHED 9-HYDROXYMETHYLANTHRACENE
Descriptor:RNA Diels-Alder ribozyme, (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION
Authors:Serganov, A., Keiper, S., Malinina, L., Tereshko, V., Skripkin, E., Hobartner, C., Polonskaia, A., Phan, A.T., Wombacher, R., Micura, R., Dauter, Z., Jaschke, A., Patel, D.J.
Deposit date:2005-01-19
Release date:2005-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
3C3Z
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO RIBOSTAMYCIN
Descriptor:HIV-1 subtype F genomic RNA, RIBOSTAMYCIN
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-01-29
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C5D
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO LIVIDOMYCIN
Descriptor:'HIV-1 subtype F genomic RNA, POTASSIUM ION, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMETHYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-01-31
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3C7R
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CRYSTAL STRUCTURE OF HIV-1 SUBTYPE F DIS EXTENDED DUPLEX RNA BOUND TO NEOMYCIN
Descriptor:HIV-1 subtype F genomic RNA, NEOMYCIN, POTASSIUM ION
Authors:Freisz, S., Lang, K., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-02-08
Release date:2008-05-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Binding of aminoglycoside antibiotics to the duplex form of the HIV-1 genomic RNA dimerization initiation site.
Angew.Chem.Int.Ed.Engl., 47, 2008
3CJZ
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EFFECTS OF N2,N2-DIMETHYLGUANOSINE ON RNA STRUCTURE AND STABILITY: CRYSTAL STRUCTURE OF AN RNA DUPLEX WITH TANDEM M22G:A PAIRS
Descriptor:RNA (5'-R(*GP*GP*AP*CP*GP*(M2G)P*AP*CP*GP*UP*CP*CP*U)-3')
Authors:Pallan, P.S., Kreutz, C., Bosio, S., Micura, R., Egli, M.
Deposit date:2008-03-14
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.
Rna, 14, 2008
3DVZ
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW4
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2650-OCH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW5
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23S RRNA, U2656-OCH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW6
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2650-SECH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA, GLYCEROL
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3DW7
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CRYSTAL STRUCTURE OF THE SARCIN/RICIN DOMAIN FROM E. COLI 23 S RRNA, U2656-SECH3 MODIFIED
Descriptor:Sarcin/Ricin Domain from E. Coli 23 S rRNA
Authors:Olieric, V., Rieder, U., Lang, K., Serganov, A., Schulze-Briese, C., Micura, R., Dumas, P., Ennifar, E.
Deposit date:2008-07-21
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:A fast selenium derivatization strategy for crystallization and phasing of RNA structures.
Rna, 15, 2009
3S7C
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CRYSTAL STRUCTURE OF A 2'-AZIDO-URIDINE-MODIFIED RNA
Descriptor:Ecoli 23 S rRNA Sarcin Ricin loop
Authors:Ennifar, E., Micura, R.
Deposit date:2011-05-26
Release date:2012-04-11
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
3S8U
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CRYSTAL STRUCTURE OF A 2-AZIDO-ADENINE-MODIFIED RNA
Descriptor:Ecoli 23 S rRNA Sarcin Ricin loop
Authors:Ennifar, E., Micura, R.
Deposit date:2011-05-31
Release date:2012-04-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling.
Acs Chem.Biol., 7, 2012
4NLF
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2'-TRIFLUOROMETHYLTHIO-2'-DEOXYCYTIDINE-MODIFIED SRL
Descriptor:23S ribosomal RNA Sarcin Ricin Loop, SULFATE ION
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-11-14
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
4NMG
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2'-TRIFLUOROMETHYLTHIO-2'-DEOXYURIDINE-MODIFIED SRL
Descriptor:23S ribosomal RNA Sarcin Ricin Loop
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-11-15
Release date:2014-11-19
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
4NXH
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2'-TRIFLUOROMETHYLTHIOURIDINE-MODIFIED E. COLI 23S RRNA SARCIN RICIN LOOP
Descriptor:23S ribosomal RNA Sarcin Ricin Loop, GLYCEROL, SULFATE ION
Authors:Ennifar, E., Micura, R., Kosutic, M.
Deposit date:2013-12-09
Release date:2014-12-10
Method:X-RAY DIFFRACTION (1.158 Å)
Cite:2'-Trifluoromethylthio-modified RNA: synthesis, X-ray structure, thermodynamic analysis, and applications
To be Published
4Y27
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E.COLI 23S SARCIN-RICIL LOOP, MODIFIED WITH A 2-ME ON G2661 AND A METHYLPHOSPHONATE ON A2662
Descriptor:27-mer SRL RNA
Authors:Ennifar, E., Micura, R., Fluer, S.
Deposit date:2015-02-09
Release date:2015-11-18
Method:X-RAY DIFFRACTION (0.998 Å)
Cite:Role of a ribosomal RNA phosphate oxygen during the EF-G-triggered GTP hydrolysis.
Proc.Natl.Acad.Sci.USA, 112, 2015
5DC3
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COMPLEX OF YEAST 80S RIBOSOME WITH NON-MODIFIED EIF5A
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-23
Release date:2016-06-01
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
J.Mol.Biol., 428, 2016
5DGE
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COPING WITH PROLINE STALLING: STRUCTURAL BASIS OF HYPUSINE-INDUCED PROTEIN SYNTHESIS BY THE EUKARYOTIC RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-27
Release date:2017-01-25
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5DGF
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING/NON-MODIFIED EIF5A AND/OR A PEPTIDYL-TRNA ANALOG
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-27
Release date:2016-12-14
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5DGV
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COMPLEX OF YEAST 80S RIBOSOME WITH HYPUSINE-CONTAINING/NON-MODIFIED EIF5A AND/OR A PEPTIDYL-TRNA ANALOG
Descriptor:Saccharomyces cerevisiae S288c RDN37-1 miscRNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Melnikov, S., Mailliot, J., Shin, B.-S., Rigger, L., Yusupova, G., Micura, R., Dever, T.E., Yusupov, M.
Deposit date:2015-08-28
Release date:2016-12-14
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5DUN
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THE CRYSTAL STRUCTURE OF OME SUBSTITUTED TWISTER RIBOZYME
Descriptor:RNA (54-MER), MAGNESIUM ION, POTASSIUM ION
Authors:Ren, A., Patel, D.J., Micura, R., Rajashankar, K.R.
Deposit date:2015-09-19
Release date:2015-10-28
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class.
Angew.Chem.Int.Ed.Engl., 54, 2015
5MRX
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27-NT SRL WITH A 5-HYDROXYMETHYL CYTIDINE MODIFICATION
Descriptor:RNA (27-MER)
Authors:Ennifar, E., Micura, R.
Deposit date:2016-12-28
Release date:2018-01-17
Method:X-RAY DIFFRACTION (0.851 Å)
Cite:Xray structure of 5hmrc-modified RNA at atomic resolution
To Be Published
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