Author results

1JC2
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COMPLEX OF THE C-DOMAIN OF TROPONIN C WITH RESIDUES 1-40 OF TROPONIN I
Descriptor:TROPONIN C, SKELETAL MUSCLE, CALCIUM ION
Authors:Mercier, P., Spyracopoulos, L., Sykes, B.D.
Deposit date:2001-06-07
Release date:2001-09-14
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure, dynamics, and thermodynamics of the structural domain of troponin C in complex with the regulatory peptide 1-40 of troponin I
Biochemistry, 40, 2001
1NPQ
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STRUCTURE OF A RHODAMINE-LABELED N-DOMAIN TROPONIN C MUTANT (CA2+ SATURATED) IN COMPLEX WITH SKELETAL TROPONIN I 115-131
Descriptor:Troponin C, Troponin I, CALCIUM ION
Authors:Mercier, P., Ferguson, R.E., Irving, M., Corrie, J.E.T., Trentham, D.R., Sykes, B.D.
Deposit date:2003-01-18
Release date:2003-04-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structure of a Bifunctional Rhodamine Labeled N-Domain of Troponin C Complexed with the Regulatory "Switch" Peptide from Troponin I: Implications for in Situ Fluorescence Studies in Muscle Fibers
Biochemistry, 42, 2003
2JMD
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SOLUTION STRUCTURE OF THE RING DOMAIN OF HUMAN TRAF6
Descriptor:TNF receptor-associated factor 6, ZINC ION
Authors:Mercier, P., Lewis, M.J., Hau, D.D., Saltibus, L.F., Xiao, W., Spyracopoulos, L.
Deposit date:2006-11-02
Release date:2007-04-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure, interactions, and dynamics of the RING domain from human TRAF6
Protein Sci., 16, 2007
2KGB
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NMR SOLUTION OF THE REGULATORY DOMAIN CARDIAC F77W-TROPONIN C IN COMPLEX WITH THE CARDIAC TROPONIN I 144-163 SWITCH PEPTIDE
Descriptor:Troponin C, slow skeletal and cardiac muscles, Troponin I, ...
Authors:Mercier, P., Julien, O., Crane, M.L., Sykes, B.D.
Deposit date:2009-03-07
Release date:2009-03-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C.
Protein Sci., 18, 2009
2LWR
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SOLUTION STRUCTURE OF RING2 DOMAIN FROM PARKIN
Descriptor:SD01679p, ZINC ION
Authors:Mercier, P., Spratt, D.E., Manczyk, N., Shaw, G.S.
Deposit date:2012-08-06
Release date:2013-06-12
Last modified:2014-10-15
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
2M9Y
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SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HHARI
Descriptor:E3 ubiquitin-protein ligase ARIH1, ZINC ION
Authors:Mercier, P., Spratt, D.E., Shaw, G.S.
Deposit date:2013-06-24
Release date:2013-11-13
Method:SOLUTION NMR
Cite:Structure of the HHARI catalytic domain shows glimpses of a HECT E3 ligase.
Plos One, 8, 2013
1PXQ
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STRUCTURE OF SUBTILISIN A
Descriptor:Subtilisin A
Authors:Kawulka, K.E., Sprules, T., McKay, R.T., Mercier, P., Diaper, C.M., Zuber, P., Vederas, J.C.
Deposit date:2003-07-04
Release date:2004-06-22
Last modified:2011-10-05
Method:SOLUTION NMR
Cite:Structure of subtilisin A, a cyclic antimicrobial peptide from Bacillus subtilis with unusual sulfur to alpha-carbon cross-links: formation and reduction of alpha-thio-alpha-amino acid derivatives
Biochemistry, 43, 2004
2JT8
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SOLUTION STRUCTURE OF THE F153-TO-5-FLUROTRYPTOPHAN MUTANT OF HUMAN CARDIAC TROPONIN C
Descriptor:Troponin C, slow skeletal and cardiac muscles
Authors:Wang, X., Mercier, P., Letourneau, P., Sykes, B.D.
Deposit date:2007-07-20
Release date:2007-08-07
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies
Protein Sci., 14, 2005
2JTZ
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SOLUTION STRUCTURE AND CHEMICAL SHIFT ASSIGNMENTS OF THE F104-TO-5-FLUROTRYPTOPHAN MUTANT OF CARDIAC TROPONIN C
Descriptor:Troponin C, slow skeletal and cardiac muscles
Authors:Wang, X., Mercier, P., Letourneau, P., Sykes, B.D.
Deposit date:2007-08-10
Release date:2007-08-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies
Protein Sci., 14, 2005
2JT3
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SOLUTION STRUCTURE OF F153W CARDIAC TROPONIN C
Descriptor:Troponin C
Authors:Wang, X., Mercier, P., Letourneau, P., Sykes, B.D.
Deposit date:2007-07-18
Release date:2007-07-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
Protein Sci., 14, 2005
1U0I
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IAAL-E3/K3 HETERODIMER
Descriptor:IAAL-E3, IAAL-K3
Authors:Lindhout, D.A., Litowski, J.R., Mercier, P., Hodges, R.S., Sykes, B.D.
Deposit date:2004-07-13
Release date:2004-10-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of a highly stable de novo heterodimeric coiled-coil
Biopolymers, 75, 2004
2JT0
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SOLUTION STRUCTURE OF F104W CARDIAC TROPONIN C
Descriptor:Troponin C, slow skeletal and cardiac muscles
Authors:Wang, X., Mercier, P., Letourneau, P.-J., Sykes, B.D.
Deposit date:2007-07-17
Release date:2008-05-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
Protein Sci., 14, 2005
2M48
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SOLUTION STRUCTURE OF IBR-RING2 TANDEM DOMAIN FROM PARKIN
Descriptor:E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION
Authors:Noh, Y.J., Mercier, P., Spratt, D.E., Shaw, G.S.
Deposit date:2013-01-30
Release date:2013-05-15
Last modified:2014-10-15
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
2MLE
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NMR STRUCTURE OF THE C-DOMAIN OF TROPONIN C BOUND TO THE ANCHORING REGION OF TROPONIN I
Descriptor:Troponin C, slow skeletal and cardiac muscles, CALCIUM ION
Authors:Robertson, I.M., Baryshnikova, O.K., Mercier, P., Sykes, B.D.
Deposit date:2014-02-26
Release date:2014-03-12
Last modified:2015-12-09
Method:SOLUTION NMR
Cite:The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I.
Biochemistry, 47, 2008
2MLF
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NMR STRUCTURE OF THE DILATED CARDIOMYOPATHY MUTATION G159D IN TROPONIN C BOUND TO THE ANCHORING REGION OF TROPONIN I
Descriptor:Troponin C, slow skeletal and cardiac muscles, CALCIUM ION
Authors:Baryshnikova, O.K., Robertson, I.M., Mercier, P., Sykes, B.D.
Deposit date:2014-02-26
Release date:2014-03-12
Last modified:2015-12-09
Method:SOLUTION NMR
Cite:The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I.
Biochemistry, 47, 2008
5C1Z
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PARKIN (UBLR0RBR)
Descriptor:E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ...
Authors:kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C23
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PARKIN (S65DUBLR0RBR)
Descriptor:E3 ubiquitin-protein ligase parkin, ZINC ION, GLYCEROL, ...
Authors:Kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5TR5
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SOLUTION STRUCTURE OF SERINE 65 PHOSPHORYLATED UBL DOMAIN FROM PARKIN
Descriptor:E3 ubiquitin-protein ligase parkin
Authors:Aguirre, J.D., Dunkerley, K.M., Mercier, P., Shaw, G.S.
Deposit date:2016-10-25
Release date:2016-12-21
Last modified:2017-01-25
Method:SOLUTION NMR
Cite:Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2N5W
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THE NMR SOLUTION STRUCTURE OF OCTYL-TRIDECAPTIN A1 IN DPC MICELLES
Descriptor:Octyl-tridecaptin A1
Authors:Cochrane, S.A., Findlay, B., Bakhtiary, A., Acedo, J.Z., Rodriguez-Lopez, E.M., Vederas, J.C.
Deposit date:2015-08-01
Release date:2016-09-28
Last modified:2016-10-26
Method:SOLUTION NMR
Cite:Antimicrobial lipopeptide tridecaptin A1 selectively binds to Gram-negative lipid II.
Proc.Natl.Acad.Sci.USA, 113, 2016
2N5Y
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SOLUTION NMR STRUCTURE OF OCTYL-TRIDECAPTIN A1 IN DPC MICELLES CONTAINING GRAM-NEGATIVE LIPID II
Descriptor:Octyl-tridecaptin A1
Authors:Cochrane, S.A., Findlay, B., Bakhtiary, A., Rodriguez-Lopez, E.M., Vederas, J.C.
Deposit date:2015-08-03
Release date:2016-09-28
Last modified:2016-10-26
Method:SOLUTION NMR
Cite:Antimicrobial lipopeptide tridecaptin A1 selectively binds to Gram-negative lipid II.
Proc.Natl.Acad.Sci.USA, 113, 2016