2M48

Solution Structure of IBR-RING2 Tandem Domain from Parkin

Summary for 2M48

• Entry DOI: 10.2210/pdb2m48/pdb
• Related: 1WD2 2JMO
• NMR Information: BMRB: 18990
• Descriptor: E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION (2 entities in total)
• Functional Keywords: parkin, ring, ibr, e3 ligase, zn-binding, ligase
• Biological source: Drosophila melanogaster (Fruit fly)
• Total number of polymer chains: 1
• Total formula weight: 15722.21

Authors

Noh, Y.J.,Mercier, P.,Spratt, D.E.,Shaw, G.S. (deposition date: 2013-01-30, release date: 2013-05-15, Last modification date: 2024-03-13)

• Primary citation: Spratt, D.E.,Julio Martinez-Torres, R.,Noh, Y.J.,Mercier, P.,Manczyk, N.,Barber, K.R.,Aguirre, J.D.,Burchell, L.,Purkiss, A.,Walden, H.,Shaw, G.S.; A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.; Nat Commun, 4:1983-1983, 2013; PubMed: 23770917; DOI: 10.1038/ncomms2983

Experimental method

SOLUTION NMR