5V45
 
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5V46
 | | Crystal structure of the I113M, F270M, K291M, L308M mutant of SR1 domain of human sacsin | | Descriptor: | Sacsin | | Authors: | Menade, M, Kozlov, G, Gehring, K. | | Deposit date: | 2017-03-08 | | Release date: | 2017-05-24 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
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5V44
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5V47
 | | Crystal structure of the SR1 domain of lizard sacsin | | Descriptor: | Lizard sacsin, SULFATE ION | | Authors: | Pan, T, Menade, M, Kozlov, G, Gehring, K. | | Deposit date: | 2017-03-08 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutations.
J. Biol. Chem., 293, 2018
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3PT3
 | | Crystal structure of the C-terminal lobe of the human UBR5 HECT domain | | Descriptor: | E3 ubiquitin-protein ligase UBR5 | | Authors: | Matta-Camacho, E, Kozlov, G, Menade, M, Gehring, K. | | Deposit date: | 2010-12-02 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structure of the HECT C-lobe of the UBR5 E3 ubiquitin ligase.
Acta Crystallogr.,Sect.F, 68, 2012
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4K95
 | | Crystal Structure of Parkin | | Descriptor: | E3 ubiquitin-protein ligase parkin, ZINC ION | | Authors: | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | | Deposit date: | 2013-04-19 | | Release date: | 2013-05-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (6.499 Å) | | Cite: | Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
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4K7D
 | | Crystal Structure of Parkin C-terminal RING domains | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, MALONATE ION, ... | | Authors: | Sauve, V, Trempe, J.-F, Menade, M, Gehring, K. | | Deposit date: | 2013-04-17 | | Release date: | 2013-05-15 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
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2MJC
 | | Zn-binding domain of eukaryotic translation initiation factor 3, subunit G | | Descriptor: | Eukaryotic translation initiation factor 3 subunit G, ZINC ION | | Authors: | Al-Abdul-Wahid, M, Menade, M, Xie, J, Kozlov, G, Gehring, K. | | Deposit date: | 2014-01-03 | | Release date: | 2015-01-07 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of the Zn-binding domain of eukaryotic translation initiation factor 3, subunit G
To be Published
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5VSZ
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5VSX
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5KES
 | | Solution structure of the yeast Ddi1 HDD domain | | Descriptor: | DNA damage-inducible protein 1 | | Authors: | Trempe, J.-F, Ratcliffe, C, Veverka, V, Saskova, K, Gehring, K. | | Deposit date: | 2016-06-10 | | Release date: | 2016-10-05 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structural studies of the yeast DNA damage-inducible protein Ddi1 reveal domain architecture of this eukaryotic protein family.
Sci Rep, 6, 2016
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4Z2Z
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2N7E
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6B3Y
 | | Crystal structure of the PH-like domain from DENND3 | | Descriptor: | DENN domain-containing protein 3 | | Authors: | Kozlov, G, Xu, J, Menade, M, Beaugrand, M, Pan, T, McPherson, P.S, Gehring, K. | | Deposit date: | 2017-09-25 | | Release date: | 2018-01-24 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.852 Å) | | Cite: | A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy.
J. Biol. Chem., 293, 2018
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3KUT
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3KUR
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3KUS
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