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4M7L
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BU of 4m7l by Molmil
Crystal structure of the complex between human tissue factor extracellular domain and antibody 10H10 FAB fragment
Descriptor: 10H10 heavy chain, 10H10 light chain, Tissue factor
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-08-12
Release date:2014-08-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structure of the complex between human tissue factor extracellular domain and antibody 10H10 FAB fragment
To be Published
4QHU
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BU of 4qhu by Molmil
Crystal Structure of IL-17A/Fab6785 complex
Descriptor: CHLORIDE ION, Fab6785 heavy chain, Fab6785 light chain, ...
Authors:Luo, J, Gilliland, G.L, Malia, T, Obmolova, G, Teplyakov, A.
Deposit date:2014-05-29
Release date:2015-08-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:IL-17A Asymmetry in a Complex with a Neutralizing Antibody Fab6785 Reveals a Potential Mechanism of Receptor Differentiation
To be Published
3QPX
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BU of 3qpx by Molmil
Crystal structure of Fab C2507
Descriptor: CADMIUM ION, CHLORIDE ION, Fab C2507 heavy chain, ...
Authors:Luo, J, Teplyakov, A, Obmolova, O, Malia, T, Gilliland, G.L.
Deposit date:2011-02-14
Release date:2011-08-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Fab C2507
To be Published
3NZH
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BU of 3nzh by Molmil
Crystal structure of anti-emmprin antibody 5F6 FAB
Descriptor: 5F6 HEAVY CHAIN, 5F6 LIGHT CHAIN, COBALT (II) ION, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2010-07-16
Release date:2011-07-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of anti-emmprin antibody 5F6 FAB
To be Published
5E2V
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BU of 5e2v by Molmil
Anti-TAU AT8 FAB with doubly phosphorylated TAU peptide
Descriptor: AT8 HEAVY CHAIN, AT8 LIGHT CHAIN, GLYCEROL, ...
Authors:Malia, T, Teplyakov, A.
Deposit date:2015-10-01
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.
Proteins, 84, 2016
5E2W
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BU of 5e2w by Molmil
Anti-TAU AT8 FAB with triply phosphorylated TAU peptide
Descriptor: AT8 HEAVY CHAIN, AT8 LIGHT CHAIN, TAU-PHOSPHOPEPTIDE
Authors:Malia, T, Teplyakov, A.
Deposit date:2015-10-01
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.
Proteins, 84, 2016
5E2T
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BU of 5e2t by Molmil
Crystal structure of anti-TAU antibody AT8 FAB
Descriptor: AT8 HEAVY CHAIN, AT8 LIGHT CHAIN, CALCIUM ION
Authors:Malia, T, Teplyakov, A.
Deposit date:2015-10-01
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.
Proteins, 84, 2016
5E2U
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BU of 5e2u by Molmil
Structure of anti-TAU AT8 FAB in the presence of phosphopeptide
Descriptor: AT8 HEAVY CHAIN, AT8 LIGHT CHAIN, SULFATE ION
Authors:Malia, T, Teplyakov, A.
Deposit date:2015-10-01
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.
Proteins, 84, 2016
4MA3
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BU of 4ma3 by Molmil
Crystal structure of anti-hinge rabbit antibody C2095
Descriptor: ACETATE ION, C2095 heavy chain, C2095 light chain, ...
Authors:Malia, T, Teplyakov, A, Gilliland, G.L.
Deposit date:2013-08-15
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.
Proteins, 82, 2014
3L5X
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BU of 3l5x by Molmil
Crystal structure of the complex between IL-13 and H2L6 FAB
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, H2L6 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-22
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
3L5W
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BU of 3l5w by Molmil
Crystal structure of the complex between IL-13 and C836 FAB
Descriptor: C836 HEAVY CHAIN, C836 LIGHT CHAIN, GLYCEROL, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-22
Release date:2010-04-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
3L7F
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BU of 3l7f by Molmil
Structure of IL-13 antibody H2L6, A humanized variant OF C836
Descriptor: CALCIUM ION, H2L6 HEAVY CHAIN, H2L6 LIGHT CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-28
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human framework adaptation of a mouse anti-human IL-13 antibody.
J.Mol.Biol., 398, 2010
7JGT
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BU of 7jgt by Molmil
Crystal Structure of FN3tt
Descriptor: Fibronectin type-III domain-containing protein
Authors:Luo, J, Malia, T.J.
Deposit date:2020-07-19
Release date:2021-07-21
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Surface salt bridges contribute to the extreme thermal stability of an FN3-like domain from a thermophilic bacterium.
Proteins, 90, 2022
5TLJ
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BU of 5tlj by Molmil
COMPLEX BETWEEN HUMAN CD27 AND FAB FRAGMENTS OF ANTIBODIES M2177 AND M2191
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2016-10-11
Release date:2017-02-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Epitope-dependent mechanisms of CD27 neutralization revealed by X-ray crystallography.
Mol. Immunol., 83, 2017
5KNG
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BU of 5kng by Molmil
CRYSTAL STRUCTURE OF ANTI-IL-13 DARPIN 6G9
Descriptor: DARPIN 6G9, GLYCEROL, PHOSPHATE ION
Authors:Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G.
Deposit date:2016-06-28
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
5KNH
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BU of 5knh by Molmil
CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13
Descriptor: ACETATE ION, DARPIN 6G9, IL13
Authors:Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G.
Deposit date:2016-06-28
Release date:2016-12-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
3L7E
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BU of 3l7e by Molmil
Crystal structure of ANTI-IL-13 antibody C836
Descriptor: ACETATE ION, C836 HEAVY CHAIN, C836 LIGHT CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-28
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Antigen recognition by antibody C836 through adjustment of VL/VH packing
Acta Crystallogr.,Sect.F, 67, 2011
5TL5
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BU of 5tl5 by Molmil
COMPLEX BETWEEN HUMAN CD27 AND ANTIBODY M2177
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD27 antigen, M2177 HEAVY CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2016-10-10
Release date:2017-06-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of CD27 in complex with a neutralizing noncompeting antibody.
Acta Crystallogr F Struct Biol Commun, 73, 2017
4PS4
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BU of 4ps4 by Molmil
Crystal structure of the complex between IL-13 and M1295 FAB
Descriptor: Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2014-03-06
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398, 2010
7T87
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BU of 7t87 by Molmil
CRYSTAL STRUCTURE OF LEUKOCIDIN AB/CENTYRIN S17/FAB 214F COMPLEX
Descriptor: Antibody Fab B214 Heavy Chain, Antibody Fab B214 Light Chain, Centyrin S17, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
7T86
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BU of 7t86 by Molmil
Crystal Structure of Fab CR5133 / Phospho-SD Peptide Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab CR5133 Heavy Chain, Antibody Fab CR5133 Light Chain, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
7T82
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BU of 7t82 by Molmil
Crystal Structure of LEUKOCIDIN E/CENTYRIN S26/FAB B438
Descriptor: Antibody Fab Heavy Chain, Antibody Fab Light Chain, Centyrin S26, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
5I1H
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BU of 5i1h by Molmil
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-20
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION
Authors:Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.222 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I1E
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BU of 5i1e by Molmil
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV1-39
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G.
Deposit date:2016-02-05
Release date:2016-06-08
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016
5I18
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BU of 5i18 by Molmil
CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV4-1
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL
Authors:Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G.
Deposit date:2016-02-05
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural diversity in a human antibody germline library.
Mabs, 8, 2016

 

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